Zyprexa and Tiredness: What Users Say

• Van...
• Taken for less than 1 month
• June 13, 2019

For Depression "Stay away! I took 15 mg Zyprexa for 2 weeks, and I feel so tired. My vision is blurry, weak hand-eye coordination, and it's difficult to speak or understand anything. Why is this drug still being prescribed?"

• Gig...
• Taken for 1 to 6 months
• April 13, 2020

For Depression "This medication Zyprexa is a miracle worker! I was in a very deep depression, suicide thoughts. I started feeling better after just a few weeks. I have been on it 6 weeks now and it keeps getting better. The doctor is now increasing it to 10mg, I feel more tired, but that will lessen as time goes by. I feel like me again!"

• Anonymous
• Taken for 1 to 6 months
• March 27, 2019

For Depression "Zyprexa made me feel very tired and irritable. I almost cussed my boyfriend over a small inconvenience. My eyesight kept blurring up, always hungry, and then I started getting this uncomfortable drowsy feeling that lasted the whole day. STAY AWAY from this garbage."

• Geo...
• November 4, 2019

For Schizophrenia "I was on Zyprexa at 25mg (had psychosis) for a few months, literally, the worst months of my life. All I wanted to do was eat and sleep, so tired and foggy, and I had no motivation. So glad I ignored doctors and got off it as soon as I possibly could. If there was an option for zero, I would give that. This stuff is utter garbage."

• Luc...
• Taken for 1 to 6 months
• May 31, 2019

For Bipolar Disorder "My boyfriend suffers from manic bipolar disorder. He was off meds for 2 years and recently became manic again. We go to the doctors and this is what she prescribed him at a dose of 3mg. It worked to stop his manic episodes. BUT he is legitimately like a zombie now. He sleeps all the time, is always tired, emotionless, unsure of himself, doesn’t talk, doesn’t eat, doesn’t laugh. He's basically a shell of himself. It’s really sad to watch, and I’m actually hoping his doctor will change his meds this week because this is NO way to live."

• NoJ...
• March 28, 2019

For Schizophrenia "I take 10 mg of Zyprexa at night, and it makes me feel like I've been chemically lobotomized. Not to mention the irritability and being tired all the time. This medication made me sleep for 10 whole hours, and I still feel sleepy after waking up. Also, my motor skills have been cut in half, I keep stumbling over stuff like I'm drunk and having blurred vision all day. This medication is a mental handicap in a bottle. How in the world does this help with schizophrenia and depression? I would not recommend this medication to anybody. Eli Lilly should be ashamed of themselves."

• dpo...
• Taken for less than 1 month
• June 16, 2023

For Depression "This drug ruined my life. I was experiencing a mild depression and wanted a 'buffer' before I started my new career in Atlanta, GA, at Emory Hospital. The night I took Zyprexa, I slept 12+ hours. I immediately started to gain weight - my lean muscle tissue was replaced by adipose tissue. I developed gynecomastia (man boobs). I was tired and irritable all day due to Zyprexa's anti-dopaminergic effects. In a frenzied effort to heal my body, I spent so much money on organic foods because no matter how healthy I ate and how much I exercised, I kept gaining weight. This drug was a nightmare and took me about 3 months of absolute terror to heal from."

• Tok...
• September 26, 2020

For Schizophrenia "I feel very sleepy, very tired. I got a brain tumor. It might be a side effect of Zyprexa or hydrochlorothiazide, a water pill. Because of Zyprexa, I gained a lot of weight and got high blood pressure, diabetes, and cholesterol."

• cma...
• Taken for less than 1 month
• July 23, 2017

For Depression "I was only on Zyprexa for 10 days, but it made me so tired I couldn't even function. All I wanted to do was sleep all day. And it made my depression worse. I was so depressed by that 10th day that I almost quit my job because I just felt like I couldn't handle any stress at all. So glad I stopped taking this drug."

• bee...
• November 4, 2015

For Depression "Sure, this med can keep depression at bay, but it can also cause some really horrible side effects. After being on this med for 1 year, I went from being a healthy 170 lbs (women's size 12) to 250 lbs (size 20). It made me so lethargic and tired. I would sleep for 14 hours a day and still be dragging out of bed. About 2 months ago was the final straw. I got blood work done by my GP, and my triglycerides were through the roof, as well as elevated blood sugar. The doc was ready to put me on meds for diabetes! I'm only 25, and I just wanted my health back, so last week I went to a new doc who got me off this horrible stuff. I feel like a new person without this toxic med in my body. Now, I'm on Viibryd."

• bee...
• November 4, 2015

For Depression "Sure, this med can keep depression at bay, but it can also cause some really horrible side effects. After being on this med for 1 year, I went from being a healthy 170 lbs (women's size 12) to 250 lbs (size 20). It made me so lethargic and tired. I would sleep for 14 hours a day and still be dragging out of bed. About 2 months ago was the final straw. I got blood work done by my GP, and my triglycerides were through the roof, as well as elevated blood sugar. The doc was ready to put me on meds for diabetes! I'm only 25, and I just wanted my health back, so last week I went to a new doc who got me off this horrible stuff. I feel like a new person without this toxic med in my body. Now, I'm on Viibryd."

• mlf...
• August 28, 2015

For Insomnia "Ok, so while I have only begun this last night... I can say I did fall asleep, which doesn't happen until after midnight, and I only woke up once to pee. I slept for almost 10 hours compared to my restless 4, if that. My only complaint so far is this entire day I have wanted to do NOTHING. I am so tired, I don't want to do anything besides sleep, and I don't like this feeling. And I can say I've been hungrier today than usual, so I'm paying attention to what I'm eating so I don't overeat... After a while, I'll update my review."

• DPD...
• Taken for less than 1 month
• October 19, 2015

For Major Depressive Disorder "Zyprexa has been a lifesaver. I was literally on the brink of suicide because of my major depression, generalized anxiety, slight bipolar II, OCD, PTSD, and depersonalization/derealization. I have been on it for about a week, and I feel a complete difference already. No more night terrors, no more worry about the littlest things, no more feeling anxious around people, and no more not feeling like my bad self again. I feel the best I've felt in 2 years because of this! All my symptoms have gone away with little side effects, despite the weight gain and lethargy an hour after taking it. I take it at night, 5 mgs, I may start taking 2.5 mgs in the morning to help the morning edge off. I heard a lot about the diabetes, hope it doesn't happen to me."

• mom...
• Taken for 1 to 6 months
• June 17, 2019

For Bipolar Disorder "Zyprexa makes you gain weight so fast. I used to be anorexic and watched out with what I ate so I stayed in shape. But this medicine makes you crave sugar and makes you feel hungry 24/7. Also, you are really, really tired. It only helps with psychotic behavior if your dose is pretty high, so you can't feel anything, and because you want to sleep all day."

• Jba...
• February 12, 2016

For Bipolar Disorder "This medication has made me extremely tired! I feel like I've lost all of my motivation. I am a teacher and a coach and find it extremely hard to get myself 'up' to do these things. I am very tired in the morning and it's not until late at night that I start to feel like myself again. Only in time to take the medication again and start the process over. It has taken away some anxiety symptoms and helped me sleep (a bit too much), but I feel down a lot because I feel like I lost my passion. I am slowly coming off of it and look forward to getting back to feeling like myself again. I empathize with people on this medication."

• Joh...
• Taken for 5 to 10 years
• June 19, 2016

For Bipolar Disorder "Zyprexa was effective at sedating me, which prevented the psychotic aspects of my manic episodes from happening very quickly. Since I only had 2 manic episodes in the span of a year, I probably should've stopped taking Zyprexa around 6 months later. Unfortunately, I took it for 5 more years, which was a massive mistake. It caused me to be very drowsy and lethargic. Because I started taking it at age 19, I didn't realize that Zyprexa was the culprit until I stopped taking it. I thought I was just a sleepy person. It had a profoundly negative impact on my life because I took it way longer than I should have."

• Ano...
• October 29, 2011

For Depression "After taking the 2.5 dosage for 4 days, I feel very irritable. I am experiencing crying spells, tiredness, extreme moodiness, and just want to be alone. This medicine was prescribed for a mood disorder that I have been experiencing. I also take other antidepressants. I don't think this is a good mix with other medicines or just not right for me."

• kry...
• September 25, 2013

For Bipolar Disorder "I have been on a 5 mg tablet for almost 2 years. I started off on one tablet a night, then cut my dose down to half a tablet, currently taking a 1/4 tablet during the day because I always miss my alarm if I take it at night. I oversleep way too much, always tired, brain feels foggy. I've gained 30 pounds, and it's getting harder to take it off. I'm always hungry and always thirsty. It helps with behaviors. I still flip out, but way less often."

• dan...
• Taken for 1 to 6 months
• March 8, 2014

For Bipolar Disorder "I would give Zyprexa a 10 rating except for the weight gain. I have bipolar 1 and have a lot more mania than depression. I have psychotic symptoms also and racing thoughts a lot. It did make me very tired the first couple of weeks, but then it worked perfectly except for the weight gain, so I am not on it anymore."

• pre...
• Taken for 1 to 6 months
• December 17, 2012

For Bipolar Disorder "I have been taking Zyprexa for over a month, and it just recently started making me sleep over 14 hours a night. I am tired and unmotivated. The anxiety has slowed way down but is not completely gone. I take 5 mg per night, and I also take Ativan 3 times a day."

• Anonymous
• December 4, 2012

For Bipolar Disorder "When I was diagnosed as bipolar, I was put on Zyprexa. I took it 3 times a day, and it was great at eliminating my mania, depression, and anxiety symptoms. However, I had two side effects: I would get tired, and I gained over 100 pounds over 12 years. So, my doctor suggested lithium, and I am on that now and doing fine, and I have lost 30 pounds in 4 months."

• Pho...
• June 23, 2021

For Bipolar Disorder "I was put on this drug because the doctor thought I was bipolar. Three years later, two psychiatrists have told me I need to get off of the Zyprexa ASAP. I was first put on 15 mg, which made me tired when I woke up. All day, I felt drugged out, and I gained 40 pounds. I am now only taking 10 mg and am lowering my dosage to 5 mg to finally get off of this drug for good. The withdrawal symptoms I have noticed from getting off Zyprexa are increased anxiety and difficulty sleeping. The best way to get off of Zyprexa with minimal problems is to taper slowly. I would rather deal with the withdrawal symptoms than being drugged out to the point I can’t function. I also take this with another antidepressant and am convinced I had symptoms similar to serotonin syndrome. Please use caution and only use this drug as a last resort option. It has a black box label for a reason. The long-term risks of staying on this drug include psychosis and medication-induced Parkinson’s disease."

• Anonymous
• October 15, 2012

For Bipolar Disorder "I found Zyprexa to be quite effective, however, it made me very tired and unmotivated, though. I was incredibly hungry all day. Only stayed on it for about a month and put on 7 lbs. I am in the process of exploring different antipsychotics that are more weight-friendly. Putting on weight was making me depressed and making me become more hostile because of it."

• sub...
• December 3, 2011

For Bipolar Disorder "I was diagnosed with bipolar disorder in the early '90s. Tried all kinds of anti-psychotic medicines, Zyprexa is the one that has helped me the best. I feel tired and emotionless, but I am pretty sure that it is better than what my family goes through when I am not on it."

• Anonymous
• June 11, 2012

For Paranoid Disorder "Zyprexa worked really well in terms of removing the paranoia and the suspiciousness. Made me normal within a period of 2-3 weeks. The only problem I feel with regard to this medicine is the weight gain issue. I think this medicine, in combination with mirtazapine, has made me put on weight in a few weeks. Yes, and also my prolactin level was well above the normal range. In the starting, this made me tired, and I had problems waking up on time. Apart from these few side effects, it is a really good antipsychotic."