Zyprexa Alternatives Compared
| Zyprexa | Caplyta | Seroquel |
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| Zyprexa (olanzapine) | Caplyta (lumateperone) | Seroquel (quetiapine) |
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Prescription only
Zyprexa is a brand (trade) name for olanzapine which is an antipsychotic that may be used to treat schizophrenia or bipolar disorder. Weight gain is common in people who take Zyprexa. Prescribed for... View more |
Prescription only
Caplyta is an atypical antipsychotic that may be used to treat adults with schizophrenia. Sedation is the most common side effect and it should not be used in people with moderate to severe liver... View more |
Prescription only
Seroquel is an antipsychotic that helps to calm and relieve psychotic thoughts. It is often given because it is quite sedating; however, care is needed because it also lowers blood pressure... View more |
Related suggestions Schizophrenia
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| More about Zyprexa (olanzapine) | More about Caplyta (lumateperone) | More about Seroquel (quetiapine) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Zyprexa has an average rating of 5.8 out of 10 from a total of 391 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 33% reported a negative effect. |
Caplyta has an average rating of 5.2 out of 10 from a total of 99 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 44% reported a negative effect. |
Seroquel has an average rating of 7.0 out of 10 from a total of 646 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Common side effects include:
See also: Zyprexa side effects in more detail. |
See also: Caplyta side effects in more detail. |
Common side effects include:
See also: Seroquel side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zyprexa prices and generic prices |
View all Caplyta prices |
View all Seroquel prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other olanzapine brands include: Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis |
N/A |
Other quetiapine brands include: Seroquel XR | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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54 hours |
18 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 640 drugs are known to interact with Zyprexa:
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A total of 572 drugs are known to interact with Caplyta:
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A total of 681 drugs are known to interact with Seroquel:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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September 30, 1996 |
December 20, 2019 |
September 26, 1997 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Patient resources | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.