Comparing Olanzapine vs Zyprexa
Olanzapine Remove Olanzapine from your drug comparison | Zyprexa Remove Zyprexa from your drug comparison |
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Olanzapine Remove Olanzapine from your drug comparison | Zyprexa olanzapine Remove Zyprexa from your drug comparison | ||||||||||||||||
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Olanzapine is an antipsychotic used in the treatment of schizophrenia and bipolar disorder. Weight gain associated with olanzapine is common. Prescribed for Agitated State, Bipolar Disorder,... View more |
Zyprexa is an antipsychotic used in the treatment of schizophrenia and bipolar disorders. Weight gain associated with Zyprexa is common. Prescribed for Bipolar Disorder, Schizophrenia, Major... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.0
For Bipolar Disorder: I was 150 pounds and I went up to 182 pounds within two months of using olanzapine. You are hungry all of the time on this medication and never feel satisfied. The first two weeks of medication use I felt very tired. I am still tired, but it's not as bad as it was. I started on 15 mg. I dropped down to 10 mg. The unpleasant side effects described continued. I am in the process of getting off this medication. |
6.2
For Bipolar Disorder: This medicine works really well as a mood stabilizer for me. The only MAJOR drawback is weight gain. I just can't control myself when the carb cravings happen. I am usually very much in control of my dietary habits, but on Zyprexa that just isn't possible. I also suffer from schizoaffective disorder and hear voices. Although Zyprexa suppresses them, it does not completely get rid of them in my case; they are quiet enough to tolerate though. I have gained 35 pounds in less than about a month and a half. I am going to wean off of these and ask the psych-doc for something else. For Bipolar Disorder: First year on 5mg at night helped my mood, anger outbursts and anxiety a great deal. Did develop high cholesterol and gained 15 pounds, but the trade off was worth it. Also helps wonderfully with insomnia. After the year mark it was no longer handling my anger well. Started having 2-3 inappropriate outbursts a week. Pdoc started me on geodon but couldn't handle the side effects, so back to the zyprexa I went with another 2.5mg added in the morning and gained another 6 pounds. Have tried other AAPs but can't handle the side effects so I'm still on the zyprexa for now until I get brave enough to try something else again. Taking with Pristiq, Trileptal, Vistiril and Xanax. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinetic muscle activity, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia. See the full olanzapine side effects document. |
Common side effects include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinetic muscle activity, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia. See the full Zyprexa side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all olanzapine prices |
View all Zyprexa prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Zyprexa, Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | Other olanzapine brands include: Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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54 hours |
54 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 597 drugs are known to interact with olanzapine:
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A total of 597 drugs are known to interact with Zyprexa:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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September 30, 1996 |
September 30, 1996 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Bipolar Disorder: Took 40mg per day for about a year before I really "came back to life." It helped me sleep but was too sedating overall. It helped me reverse anorexia but I doubled my weight (gained 93 lbs in a few months.) It did stop the psychosis. Was able to feel emotions again after years of numbness. Took varying doses for 17 yrs and had very hard time getting off it when the time was right. Have been off 5 months now and am considering starting again because of severe insomnia & mood swings. Hate the weight gain and lethargy.