Comparing Prazosin vs Trazodone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Prazosin	Trazodone	Enter another drug to compare

Prazosin

Trazodone

Prescription only

Prazosin effectively treats high blood pressure but commonly causes dizziness or lightheadedness on initiation or with a dosage increase. However, a tolerance to this effect develops on continued... View more

Prescription only

Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more

More about Prazosin

More about Trazodone

Ratings & Reviews

Prazosin has an average rating of 6.9 out of 10 from a total of 281 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect.

Trazodone has an average rating of 6.3 out of 10 from a total of 1438 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect.

View all 281 reviews

View all 1438 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dizziness (12.5%)
Nightmares (10.0%)
Anxiety (4.6%)
Headaches (4.6%)
Tiredness (4.6%)
Vivid dreams (4.6%)
Nausea (4.3%)

View all Prazosin side effects

Drowsiness (17.7%)
Headaches (9.5%)
Dizziness (8.6%)
Anxiety (5.9%)
Dry mouth (5.8%)
Tiredness (4.9%)
Insomnia (4.6%)

View all Trazodone side effects

Drug Class

Antiadrenergic agents, peripherally acting

Phenylpiperazine antidepressants

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	2 mg
Per unit^*	$1.03
Cost^*	$102.57

View all Prazosin prices

Quantity	100 each
Strength	50 mg
Per unit^*	$0.20 - $0.21
Cost^*	$20.37 - $20.92

View all Trazodone prices

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Dosage Forms

Oral capsule

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4 hours

7.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 274 drugs are known to interact with Prazosin:

9 major drug interactions (24 brand and generic names)
263 moderate drug interactions (1322 brand and generic names)
2 minor drug interactions (4 brand and generic names)

A total of 674 drugs are known to interact with Trazodone:

138 major drug interactions (504 brand and generic names)
521 moderate drug interactions (2175 brand and generic names)
15 minor drug interactions (71 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Ask your doctor before using prazosin together with alcohol. Using prazosin with alcohol can lower... View more

Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

June 23, 1976

December 24, 1981

WADA Class View classifications

N/A

More Information

Patient Resources

Prazosin uses

Trazodone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Prazosin vs Trazodone

See also:

Flomax

Cialis

Cosentyx

Proscar

Adcirca

Dutasteride

Terazosin

Alfuzosin

Doxazosin

Tadalafil

Further information

Comparing Prazosin vs Trazodone

See also:

Further information

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