Comparing Paroxetine vs Trintellix
| Paroxetine | Trintellix (vortioxetine) |
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| Paroxetine | Trintellix (vortioxetine) |
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Prescription only
Paroxetine may be used in the treatment of depression or anxiety disorders. Common side effects include headaches and nausea. Taking paroxetine with other medications such as tramadol that also... View more |
Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin... View more |
Related suggestions Popular comparisons
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| More about Paroxetine | More about Trintellix (vortioxetine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Paroxetine has an average rating of 7.1 out of 10 from a total of 1550 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
Trintellix has an average rating of 6.0 out of 10 from a total of 1129 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Paroxetine side effects |
View all Trintellix side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Paroxetine prices |
View all Trintellix prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Brisdelle, Paxil, Paxil CR |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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21 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 510 drugs are known to interact with Paroxetine:
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A total of 355 drugs are known to interact with Trintellix:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 29, 1992 |
September 30, 2013 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.