Nitrofurantoin Alternatives Compared
| Nitrofurantoin | Ciprofloxacin | Macrobid (nitrofurantoin) |
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| Nitrofurantoin | Ciprofloxacin | Macrobid (nitrofurantoin) |
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Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescription only
Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18. In adults, it should be reserved for infections that... View more |
Prescription only
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection. Macrobid may also be used for purposes not listed in this medication guide. |
Related suggestions Urinary Tract Infection
Bladder Infection
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| More about Nitrofurantoin | More about Ciprofloxacin | More about Macrobid (nitrofurantoin) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1878 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 52% reported a negative effect. |
Ciprofloxacin has an average rating of 5.0 out of 10 from a total of 935 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 46% reported a negative effect. |
Macrobid has an average rating of 4.5 out of 10 from a total of 827 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 51% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Nitrofurantoin side effects |
View all Ciprofloxacin side effects |
View all Macrobid side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nitrofurantoin prices |
View all Ciprofloxacin prices |
View all Macrobid prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Furadantin, Macrobid, Macrodantin | Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR | Other nitrofurantoin brands include: Furadantin, Macrodantin | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
4 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 220 drugs are known to interact with Nitrofurantoin:
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A total of 716 drugs are known to interact with Ciprofloxacin:
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A total of 220 drugs are known to interact with Macrobid:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 06, 1953 |
October 22, 1987 |
December 24, 1991 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.