Nitrofurantoin Alternatives Compared
| Nitrofurantoin | Ciprofloxacin | Macrobid (nitrofurantoin) |
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| Nitrofurantoin | Ciprofloxacin | Macrobid (nitrofurantoin) |
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Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescription only
Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18. In adults, it should be reserved for infections that... View more |
Prescription only
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection. Macrobid may also be used for purposes not listed in this medication guide. |
Related suggestions Urinary Tract Infection
Bladder Infection
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| More about Nitrofurantoin | More about Ciprofloxacin | More about Macrobid (nitrofurantoin) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1880 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 52% reported a negative effect. |
Ciprofloxacin has an average rating of 5.0 out of 10 from a total of 936 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 46% reported a negative effect. |
Macrobid has an average rating of 4.5 out of 10 from a total of 827 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 51% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Nitrofurantoin side effects |
View all Ciprofloxacin side effects |
View all Macrobid side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nitrofurantoin prices |
View all Ciprofloxacin prices |
View all Macrobid prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Furadantin, Macrobid, Macrodantin | Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR | Other nitrofurantoin brands include: Furadantin, Macrodantin | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
4 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 222 drugs are known to interact with Nitrofurantoin:
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A total of 717 drugs are known to interact with Ciprofloxacin:
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A total of 222 drugs are known to interact with Macrobid:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 06, 1953 |
October 22, 1987 |
December 24, 1991 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.