Comparing Bactrim vs Nitrofurantoin
| Bactrim | Nitrofurantoin |
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| Bactrim (sulfamethoxazole / trimethoprim) | Nitrofurantoin |
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Prescription only
Bactrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly... View more |
Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Related suggestions Urinary Tract Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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| More about Bactrim (sulfamethoxazole / trimethoprim) | More about Nitrofurantoin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Bactrim has an average rating of 5.5 out of 10 from a total of 614 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 42% reported a negative effect. |
Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1856 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 52% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Bactrim side effects in more detail. |
See also: nitrofurantoin side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Bactrim prices |
View all nitrofurantoin prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other sulfamethoxazole / trimethoprim brands include: Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Co-trimoxazole, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric View more | Furadantin, Macrobid, Macrodantin | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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14 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 422 drugs are known to interact with Bactrim:
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A total of 196 drugs are known to interact with nitrofurantoin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 30, 1973 |
February 06, 1953 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.