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Bactrim and Fever: What Users Say

Fever: mentioned by 50 users (8.1%)

Based on user experiences from 616 Bactrim reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 19.6%
headaches 16.9%
anxiety 11.2%
rash 10.6%
fever 8.1%
dizziness 7.5%
loss of appetite 6.8%
itching 6.7%
chills 6.3%
allergic reaction 5.5%

Reviews for Bactrim

Commonly mentioned side effects
  • Ril...
  • Taken for less than 1 month
  • May 13, 2021

For Bacterial Infection "I had a breast infection and was prescribed this terrible medicine. It needs to be off the market. I felt real bad the second day taking it. It caused a fever, rash, headache, sharp pains throughout my body, no appetite, shakiness, dizziness, and numbness. I felt so out of it, it scared me so bad I stopped taking it. The Bactrim medicine is too strong. I definitely wouldn’t recommend!"

2 / 10
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  • Anonymous
  • October 9, 2009

For Urinary Tract Infection "I never had an allergic reaction until I took this medication. Now I learned the hard way I'm allergic to sulfa drugs. After one dose, I had a lot of serious side effects: high fever, intense stomach pain, insomnia, hallucinations, anxiety, non-stop chills/shaking, vomiting, and rash. Needless to say, I ended up in the hospital for 3 days. I think that you need to be careful when taking the drug and be aware of all the serious side effects."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 13, 2020

For Urinary Tract Infection "This drug is terrible! Run if the doctor prescribes this. Day 1, I had a headache and aches to my kidneys. Like I could literally feel the pain in my kidneys! I felt bloated, vomiting, fever of 101, pain in my kidneys, jittery, and chills. Please, please don't take it. The ratio of the ones that had no symptoms to the ones who did is a big difference! I took it for 2 days, then threw the rest down the toilet. The ONLY good thing was I took 1 dose, and the next day felt relief... but still... eff this stuff!"

1 / 10
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Frequently asked questions

  • Anonymous
  • December 20, 2011

For Bacterial Infection "This was not right for me. I had a severe reaction while taking this and had to go to the emergency room. Racing/irregular heartbeat, nausea, shaky legs felt weird, red blotches, slurring speech, red eyes, feverish, and generally felt very unwell."

1 / 10
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  • Des...
  • Taken for less than 1 month
  • February 15, 2016

For Urinary Tract Infection "They prescribed Bactrim to me, worst thing ever. Ended up in the hospital, body aches, fever, insomnia... & went to the hospital. Ended up with a low blood count, ran all kinds of tests. It was just awful. I will never take this again, and it's been about a month, and I'm still not 100% better. I will never take this ever again!"

1 / 10
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  • BWa...
  • February 19, 2020

For Meningitis "The ER doctor prescribed him Bactrim to help with the forever ear infection. My son was taking the antibiotics for 2 weeks when he began experiencing symptoms like meningitis. He complained of his head hurting, stiff neck, back pain, sore throat, fever, and stomach ache. Took him to the ER, they did blood work and different tests and found nothing wrong. The doctor sent me home, told me to continue the antibiotics. I gave it to him again, and again the same reaction. I stopped giving it to him, and he broke out with this massive rash that burned and itched. He itched for a week. I did research on this drug and found out this drug can cause aseptic meningitis, I was poisoning my kid! On further research, I found this drug can alter blood tests so that they would not know to look for meningitis. The scariest part is the medical professionals missed this and told me to keep giving this poison to my child. I hate this drug! It is the worst drug to give anyone! I paid $151 to poison my child."

1 / 10
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  • Bac...
  • Taken for less than 1 month
  • September 22, 2020

For Bacterial Skin Infection "Prescribe Bactrim 2 days for 10 days for a stye. On the 7th day, I had my allergic reaction. All-over body rash, fever, chills, severe leg pain, chemical burns/ulcers in all soft tissue areas (nose, eyes, mouth, and 'down below'...), abdominal pain, diarrhea, zero appetite, headache, nausea, elevated kidney function test. Bactrim is known and has a long history of hurting more than helping. Stay away!!"

1 / 10
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More FAQ

  • Cap...
  • Taken for less than 1 month
  • October 15, 2019

For Urinary Tract Infection "Horrible, horrible medication. I was put on a 7-day course of Bactrim for a fairly mild UTI by local urgent care, and the day after starting my dosage, I experienced SEVERE heightened anxiety, panic attacks, low fever, back tension and pain, uncontrollable shaking, and insomnia. Some hallucinations and nausea as well. After day three, I couldn’t take it any longer and stopped taking it— most of the severe symptoms went away within 24 hours, but it’s been almost 3 days since quitting, and my muscle pain and anxiety are still far worse than they were before taking Bactrim."

1 / 10
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  • Jan...
  • May 10, 2019

For Urinary Tract Infection "Took Bactrim for a UTI. I had never taken it before. At day 3, I started feeling horrible, short of breath, and intense stomach pain. I had never had a UTI before, so I assumed this might be just a bad UTI. Day 6, I was shaking with chills and could not pee AT ALL. Went to the ER, I had a fever, high eosinophils, and a very elevated creatinine. Turns out I had an acute kidney injury from Bactrim. I was given fluids, and I woke up the next morning covered in the most painful drug rash. That rash lasted two weeks. Not to mention, I was put on prednisone for the rash and because I had interstitial nephritis. The prednisone drove me out of my mind. Awful experience."

1 / 10
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  • Nor...
  • Taken for less than 1 month
  • October 15, 2019

For Urinary Tract Infection "This has been so scary. I went to doctors for a routine check-up, it turns out I have a UTI for which they prescribed Bactrim. Three days into the Bactrim, I was not feeling good-lightheaded, sick to my stomach, my head and face were burning up on fire, unbearable headache. Day 4, I ran a fever of 102.9 all day. Days 5 and 6 got worse, I couldn't even stand, couldn't sleep, the pain was unbearable from the tip of my head to the bottom of my feet. Day 7, I made it early in the morning to the doctors to see what was going on. Turns out (as the doc called it), a really drastic allergic reaction to this Bactrim. The doctor said, one more day and I would have ended up in the ICU. Today is day 8, and I'm still sitting here in excruciating pain. I called the doctor back and am waiting for an answer. I'm having trouble using my hands, and it's very painful to walk. So my suggestion is, if you feel ill after taking Bactrim, see your doctor soon."

1 / 10
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  • Anonymous
  • August 29, 2020

For Bacterial Skin Infection "Took Bactrim for folliculitis. First 7 days I only had vomiting and nausea, but on Day 8 I started getting fevers, intense shaking, throbbing headache, sweating, vomiting, insomnia, depression. I never felt this sick ever. It took me a while to realize it was the antibiotic. Once I stopped taking it, I broke out in a rash. Ended up having a sulfa allergy. Please be cautious when taking this. There was one point where I just wanted to call 911, I was in so much agony... It did help clear up much of the infection."

2 / 10
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  • Fel...
  • December 12, 2009

For Bacterial Infection "I was on Bactrim for 10 days because of a Bartholin cyst that tested positive for MRSA. On the 7th day, I started experiencing back pain, intermittent low-grade fevers, chills, complete fatigue, and eyeball pain. An I.D. doctor wanted me to take it for another 7 days as a precaution, but I had to force him to listen to my symptoms, and he told me to stop taking the Bactrim. Also, don't know if it matters that I'm not of 'normal' weight for most women, at 5'5", I'm 109 lbs - the symptoms I experienced were also listed as possible 'overdose'... stopped Bactrim today - feel terrible."

4 / 10
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  • Anonymous
  • April 28, 2011

For Bacterial Infection "Pain and swelling in the vicinity of my tailbone led to an emergency room visit where I had a pilonidal cyst drained. After the doctor incised and drained my cyst, he prescribed me Bactrim and Keflex. He explained that the Keflex was intended to treat the infection if it was MRSA while Bactrim would cover all other bases. A week into my 10-day course of antibiotics, I went to bed with a developing fever. In the morning, I awoke to discover that my entire body was covered in a red, splotchy rash. I immediately went to a medical professional who informed me that I was likely having a severe allergic reaction to Bactrim. I was informed that my fever and rash would persist for days to weeks and may progress to anaphylaxis."

2 / 10
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  • KCa...
  • December 12, 2019

For Urinary Tract Infection "Took one dose of Bactrim for my UTI. Within 20 minutes, I felt really itchy. About an hour later, my chest became really tight, so I went to urgent care. I felt so sick, I couldn’t walk. I fell down on the sidewalk, throwing up on my way into the building. It caused severe vomiting and diarrhea. My heart rate was 120, and I had a fever. I ended up having to get an IV and finally felt okay enough after many hours at the hospital. I will absolutely never take this medication again."

1 / 10
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  • Ell...
  • Taken for less than 1 month
  • May 3, 2015

For Urinary Tract Infection "Was prescribed Bactrim by a walk-in clinic. Should've known better. After 2 days, I experienced some awful side effects - chills, fevers, night sweats, insomnia, diarrhea, and migraines - for three days. I thought I was going to die. After I finished my prescription, I got this terrible head-to-toe rash that itches like crazy. My UTI is gone, but it was not worth the rash and three days of near death. Does anyone know what I can do for this rash?"

3 / 10
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  • Sic...
  • Taken for less than 1 month
  • October 7, 2020

For Bacterial Skin Infection "Had an abscess removed and was prescribed Bactrim. Could not stay awake and got more sick every time I took it. Had most of the symptoms they say to contact your doctor about. Called and was told unless I had a rash, there was no reason not to keep taking it. I could not function, had an extreme migraine, which I have never had before (sensitivity to light and sound). Upset stomach, trouble passing urine, leg pain, chills, fever, among others."

1 / 10
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  • Dra...
  • March 31, 2018

For Prostatitis "Bad side effects to the extent that I had to stop after 2 days. Flu-like symptoms, bad headache, pain in muscles and joints, low fever, no energy, could not eat, nausea - you name it, I had it. Too bad as I think it was starting to knock down my bacterial prostatitis. The flu-like symptoms were so convincing that I stopped for a few days, felt better, then started again just to make certain I didn't have the flu."

1 / 10
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15 Report
  • Kat...
  • Taken for less than 1 month
  • October 29, 2019

For Urinary Tract Infection "Was prescribed Bactrim for a UTI. Terrible side effects! I thought I had caught the flu, but when I went into the doctor, she said it was just a reaction to Bactrim. Fever (super uncomfortable, sweating and chills), body/joint aches and pains, extreme fatigue. Felt so sick and run down I didn’t want to get out of bed. The day after my last dose, I developed a bright red rash everywhere, which felt like it burned and itched. I had the worst week ever with this drug."

2 / 10
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  • Ant...
  • October 14, 2017

For Urinary Tract Infection "First time prescribed Bactrim for a mild UTI. Second day I had flu-like symptoms. After day 4, I was feeling so poorly I went to the ER, where I was told just flu and to rest and to finish Bactrim so it will clear up UTI. Day 5, fever of 105, rushed to the hospital where I passed out. Completely dehydrated and organs were showing signs of sepsis. I was in the ICU unit for 3 days. The diagnosis was “allergy to sulfa.” However, that’s not really an allergic response. I think it causes the body to dehydrate faster than normal, and my actual problem was intense dehydration. Bactrim was banned in the UK after a number of people died. I’ll never take it again."

1 / 10
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  • Cas...
  • August 9, 2017

For Urinary Tract Infection "I was prescribed Bactrim for a UTI, and after one dose, I immediately developed a splitting headache, followed later by weakness, body aches, chills, fever, slight nausea, cough, and sore throat. I feel as if I have the flu. I suppose the medication did do what it was supposed to do because the UTI feels as if it's almost completely gone (I'm sure it isn't, but at least it doesn't hurt). I will say I don't think the side effects are worth it. I'm in a lot of pain and discomfort, and I think I'll be going to the emergency room just to be on the safe side."

2 / 10
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  • Whi...
  • Taken for less than 1 month
  • February 19, 2017

For Bacterial Infection "I had a bacterial infection and feeling ill, and the doctor prescribed Bactrim. I didn't think it was helping as my illness took a turn for the worst. I had fever, chills, muscle weakness and pain, stomach pain, and I couldn't get out of bed. I'd start to feel better after a few hours and thought it was finally working. Nope. I took my next dose of Bactrim and all the symptoms came back full strength, and I was severely ill again. I finally linked it to Bactrim and stopped taking it. My symptoms cleared up over the course of a few days. I learned my grandmother and mother have a severe sulfa allergy, and I found out the hard way I do too. Words just don't describe how sick I was on this medication."

1 / 10
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  • Jol...
  • Taken for less than 1 month
  • April 21, 2021

For Urinary Tract Infection "I had the worst experience with Bactrim. The first day, I had a 101.8 fever, chills, uncontrollable shaking, anxiety, rash, and fast heartbeat. The next day, I was extremely achy, nauseous, and could not eat anything the whole day. I stopped taking it after the second day, and my symptoms are getting better after a day, but I still feel cruddy and have a bad headache."

1 / 10
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10 Report
  • Hal...
  • Taken for less than 1 month
  • January 14, 2021

For Urinary Tract Infection "I was prescribed this medication for a UTI. After 1 pill, I woke up feeling nauseous, nonstop vomiting, bloating, diarrhea, headaches, insomnia, dizziness, weakness, loss of appetite, fever, chills. I am currently on day 3 and will not be taking this anymore. I have zero improvements, which is to be expected after only 3 days. I was told to take 2 pills daily for 10 days. I can’t take the extreme side effects, and I don’t see why a doctor would prescribe this, with this many horrible side effects. I thought I had a stomach bug or food poisoning until I decided to look up the side effects and realized it’s the medicine. My kind was 800/160MG TB. I don’t recommend."

1 / 10
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  • Cry...
  • Taken for less than 1 month
  • October 23, 2019

For Bacterial Skin Infection "I had an inflamed bug bite on my leg and was prescribed Bactrim. I ate and took the first and only dose that night at around 8 pm. Around 3ish in the morning, my head was throbbing, I was insanely warm with a 102-degree fever, meanwhile having chills at the same time. What bothered me the most is my hands swelled, were red, and I had intense itching. I'm still experiencing these symptoms, so I don't know when they will stop."

2 / 10
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  • ind...
  • February 7, 2011

For Urinary Tract Infection "Today was the first day I took this medication. Two hours after, I experienced joint pain, blurred vision, back pain, a headache, chills, fever, nausea, cough, and sore throat. This was in addition to my already severe urinary tract infection symptoms, which I was sent to the ER for the night before, including severe pain in the pelvis, achy back (kidneys). Although symptoms of a severe UTI can also be fever, pain in the flank (pain that runs along the back at about waist level), chills, and nausea, I believe the medication gave me the additional symptoms. I was fine all day long until around two hours after taking the pill. After about 3 hours, symptoms increasingly went away. I am not sure if the pills are working or if they wore off."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.