Bactrim Alternatives Compared
| Bactrim | Ciprofloxacin | Nitrofurantoin |
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| Bactrim sulfamethoxazole / trimethoprim | Ciprofloxacin | Nitrofurantoin |
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Bactrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly... View more |
Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18 and in adults, it should be reserved for infections... View more |
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Choose a suggestion below Urinary Tract Infection
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| More about Bactrim (sulfamethoxazole / trimethoprim) | More about Ciprofloxacin | More about Nitrofurantoin | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Bactrim has an average rating of 5.3 out of 10 from a total of 575 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 44% reported a negative effect. |
Ciprofloxacin has an average rating of 5.0 out of 10 from a total of 863 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 47% reported a negative effect. |
Nitrofurantoin has an average rating of 4.3 out of 10 from a total of 1729 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 53% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full Bactrim side effects document. |
Commonly reported side effects include: pyelonephritis, arthralgia, musculoskeletal signs and symptoms. See the full ciprofloxacin side effects document. |
See the full nitrofurantoin side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Bactrim prices and generic prices |
View all ciprofloxacin prices |
View all nitrofurantoin prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other sulfamethoxazole / trimethoprim brands include: Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Co-trimoxazole, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric View more | Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR | Furadantin, Macrobid, Macrodantin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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14 hours |
4 hours |
1 hour |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 389 drugs are known to interact with Bactrim:
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A total of 622 drugs are known to interact with ciprofloxacin:
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A total of 178 drugs are known to interact with nitrofurantoin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 30, 1973 |
October 22, 1987 |
February 06, 1953 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.