Comparing Metronidazole vs Xifaxan
| Metronidazole | Xifaxan (rifaximin) |
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| Metronidazole | Xifaxan (rifaximin) |
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Prescription only
Metronidazole is an antibiotic that is particularly effective at treating infections caused by susceptible anaerobic bacteria and parasites. Alcohol and products containing propylene glycol should... View more |
Prescription only
Prescribed for Hepatic Encephalopathy, Irritable Bowel Syndrome with Diarrhea, Irritable Bowel Syndrome, Traveler's Diarrhea, Diarrhea. Xifaxan may also be used for purposes not listed in this... View more |
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| More about Metronidazole | More about Xifaxan (rifaximin) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Metronidazole has an average rating of 6.0 out of 10 from a total of 2432 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 29% reported a negative effect. |
Xifaxan has an average rating of 6.6 out of 10 from a total of 96 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Metronidazole side effects |
View all Xifaxan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Metronidazole prices |
View all Xifaxan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Flagyl, Flagyl 375, Flagyl IV, Likmez, Metro, Metro IV |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
10.19 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 389 drugs are known to interact with Metronidazole:
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A total of 91 drugs are known to interact with Xifaxan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 18, 1963 |
May 25, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.