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Xifaxan and Pain: What Users Say

Pain: mentioned by 4 users (4.2%)

Based on user experiences from 96 Xifaxan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bloating 15.6%
diarrhea 13.5%
gas 11.5%
constipation 9.4%
nausea 5.2%
cramps 4.2%
pain 4.2%
upset stomach 4.2%
brain fog 3.1%
depression 3.1%

Reviews for Xifaxan

Commonly mentioned side effects
  • Lul...
  • August 25, 2018

For Irritable Bowel Syndrome with Diarrhea "I took this drug for my IBS-C. While I was on it, it did help with my pains but not my bloating after I ate. It actually made me more constipated than before. Just a week after my last pill, I can't eat anything without having pain and a swollen stomach, including gluten-free. Just a way for the doctors to get a kickback or a percentage! Sad world that we are living in."

3 / 10
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30 Report
  • Kmi...
  • Taken for less than 1 month
  • December 14, 2018

For Irritable Bowel Syndrome with Diarrhea "Do not take this drug! It made my symptoms of small intestinal bacterial overgrowth (SIBO) ten times worse. Before taking the drug, I had very mild symptoms, just some light feelings of hunger after eating. Now, six days after finishing a two-week course, I’m doubled over in pain, severely constipated, severely depressed, unable to sleep, and in a constant state of emergency. I’m worried that now I have IBS. Please do not take this drug."

1 / 10
Was this helpful?YesNo
69 Report
  • Sha...
  • Taken for less than 1 month
  • June 19, 2019

For Irritable Bowel Syndrome with Diarrhea "I have IBS-mostly D and lots and lots of lower abdominal cramping that I can't get under control. My Dr. prescribed this for me to help control the cramping. It seemed to work for the first few days, and then BAM! Stomach pain, and sharp shooting pains in my rectum and lower abdomen! So I stopped taking it. Also, my frequency to the bathroom did not change, nor did the D."

2 / 10
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13 Report

See also:

  • can...
  • Taken for less than 1 month
  • December 30, 2017

For Irritable Bowel Syndrome with Diarrhea "Do not take this drug unless you have been diagnosed with small intestinal bacterial overgrowth (SIBO). I was given this drug by a new GI after I told him that I had been tested for SIBO with negative results. The drug made me incredibly bloated, made the diarrhea worse, and my stomach was in constant pain. This might be effective if you have SIBO, but if you do not, do not take this drug. Not to mention, even with insurance coverage, my co-pay for a 2-week supply was around $500. I just totally wasted my money on this (yet again, useless drug)."

1 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.