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Xifaxan and Upset Stomach: What Users Say

Upset stomach: mentioned by 4 users (4.2%)

Based on user experiences from 95 Xifaxan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bloating 15.8%
diarrhea 13.7%
gas 11.6%
constipation 9.5%
nausea 5.3%
cramps 4.2%
pain 4.2%
upset stomach 4.2%
brain fog 3.2%
depression 3.2%

Reviews for Xifaxan

Commonly mentioned side effects
  • Lyn...
  • October 5, 2015

For Irritable Bowel Syndrome with Diarrhea "AWFUL MEDICATION. I was on Xifaxan for a week and a half when it started giving me crippling stomach cramps every time I ate. The cramps have persisted three weeks beyond stopping the medication and I can only eat plain rice/pasta and peas. It also didn't do what it was prescribed to do and I still have symptoms of IBS. All it did was give me a side effect that makes me not able to eat."

1 / 10
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83 Report
  • MR ...
  • Taken for less than 1 month
  • December 14, 2019

For Irritable Bowel Syndrome with Diarrhea "Xifaxan was prescribed to help my IBS. My stomach tolerated it for 4 days, but now I can’t stay out of the bathroom. It has destroyed my stomach, and I have been taking Pepto and Imodium to slow it down, but to no avail. Be careful, this can wreck your stomach. I regret taking it."

1 / 10
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46 Report
  • Tex...
  • Taken for less than 1 month
  • July 3, 2019

For Irritable Bowel Syndrome with Diarrhea "So far, this is great! Did experience a queasy stomach the first few days, but now all is good. But not a cure-all. If you have other food intolerances, this will not correct those. I am still mindful of what I eat. No sodas, greasy foods, milk (I use almond), or chocolate. These items cause me trouble regardless. I think this will work for me, at least I can eat without looking for the nearest bathroom."

9 / 10
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16 Report
  • Che...
  • July 15, 2017

For Irritable Bowel Syndrome with Diarrhea "I have IBS with diarrhea. Out of pocket price $500.00 for Xifaxan 550 mg, three pills a day. It did not work for me at all. After two weeks of the pills diligently taken, waste of money. I had no side effects, but the pills did not work for me, the diarrhea persists, as does nausea, sweating, and stomach cramps. I have run out of ideas, as has the doctor. Don't waste your money."

1 / 10
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21 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.