Comparing Methadone vs Vivitrol
| Methadone | Vivitrol (naltrexone) |
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| Methadone | Vivitrol (naltrexone) |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Vivitrol is used for the treatment of alcohol or opioid addiction alongside social therapy and psychotherapy. It is administered by intramuscular injection by a health professional once every four... View more |
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| More about Methadone | More about Vivitrol (naltrexone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Methadone has an average rating of 8.7 out of 10 from a total of 606 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
Vivitrol has an average rating of 7.5 out of 10 from a total of 203 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methadone side effects |
View all Vivitrol side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methadone prices |
View all Vivitrol prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Methadone Diskets, Methadose, Methadose Sugar-Free |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 836 drugs are known to interact with Methadone:
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A total of 352 drugs are known to interact with Vivitrol:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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August 13, 1947 |
April 13, 2006 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.