Mercaptopurine Alternatives Compared
| Mercaptopurine | Pentasa | Humira |
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| Mercaptopurine | Pentasa mesalamine | Humira adalimumab |
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Prescribed for Acute Lymphoblastic Leukemia. May also be prescribed off label for Crohn's Disease - Maintenance, Crohn's Disease - Acute, Autoimmune Hepatitis, Inflammatory Bowel Disease, Intestinal... View more |
Prescribed for Crohn's Disease - Maintenance, Inflammatory Bowel Disease, Ulcerative Colitis - Maintenance, Ulcerative Colitis - Active, Ulcerative Proctitis, Ulcerative Colitis. Pentasa may also be... View more |
Humira is a TNF-alfa inhibitor that may be used to treat a wide range of different inflammatory conditions, such as Rheumatoid Arthritis, psoriasis, ankylosing spondylitis, Crohn's disease, and... View more |
Choose a suggestion below Crohn's Disease, Maintenance
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| More about Mercaptopurine | More about Pentasa (mesalamine) | More about Humira (adalimumab) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Mercaptopurine has an average rating of 6.1 out of 10 from a total of 30 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 33% reported a negative effect. |
Pentasa has an average rating of 7.6 out of 10 from a total of 74 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 9% reported a negative effect. |
Humira has an average rating of 6.3 out of 10 from a total of 631 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full mercaptopurine side effects document. |
See the full Pentasa side effects document. |
Common side effects include: upper respiratory tract infection, headache, injection site reaction, skin rash, antibody development, sinusitis, pain at injection site. See the full Humira side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all mercaptopurine prices |
View all Pentasa prices and generic prices |
View all Humira prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Purinethol, Purixan | Other mesalamine brands include: Apriso, Asacol, Asacol HD, Canasa, Canasa Pac, Delzicol, Lialda, Rowasa, Rowasa Sulfite Free, Zaldyon View more | Other adalimumab brands include: Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz, Yusimry | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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2 hours |
10 hours |
480 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
Excluding Asacol And Asacol HD
Category C
Risk cannot be ruled out
Asacol And Asacol HD See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 238 drugs are known to interact with mercaptopurine:
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A total of 115 drugs are known to interact with Pentasa:
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A total of 420 drugs are known to interact with Humira:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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September 11, 1953 |
May 10, 1993 |
December 31, 2002 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.