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Entyvio and Pain: What Users Say

Pain: mentioned by 8 users (4.9%)

Based on user experiences from 162 Entyvio reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 14.8%
joint pain 13.0%
hair loss 9.9%
headaches 8.6%
tiredness 8.6%
diarrhea 4.9%
pain 4.9%
nausea 4.3%
rash 3.7%
chills 3.1%

Reviews for Entyvio

Commonly mentioned side effects
  • MCC...
  • Taken for 1 to 6 months
  • September 8, 2018

For Ulcerative Colitis "Entyvio saved my life, both socially and physically. I went through Lialda, Uceris, Prednisone, Canasa, and so on! These drugs could only help the upper portion of my colon, but not my proctitis, pain, urgency, and tenesmus. Entyvio worked for me! Symptom-free after ONE dose :) Going in for my 4th dose."

10 / 10
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42 Report
  • Han...
  • March 13, 2019

For Crohn's Disease "Entyvio caused a lot of pain to my body. My joints started popping out of place. Started with my toes popping out of socket, I would have to pop them back in a couple of times a day for over a month. My hip dislocated, shoulder, fingers, and jaw pop out of socket. I had hundreds of knots form in my back. I ended up being hospitalized for several days due to a partial bowel blockage, this was several months after starting Entyvio, so it should've been fully built up in my system. Entyvio was absolutely terrible in all aspects for me, and I would never recommend it for anyone. Don't waste your time, money, and health on it."

1 / 10
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36 Report
  • Hal...
  • February 13, 2017

For Ulcerative Colitis "I haven't been able to tolerate any drug during the 5 years I have been officially flaring and diagnosed with UC. Despite this, I know I had this nasty thing for the past 20 years. To put it plainly, Humira worked for 2 months, then failed. Now Entyvio worked for 1 month maybe and seems to be placebo now. I oscillate between very bad bloating and constipation and then diarrhea. Since on Entyvio, I am unable to sleep laying down from the pain, and I have no ability to form a normal stool - it's either diarrhea or it's pencil thin or pebble-like. I do not feel like this medicine works and is just another step in the long journey toward surgery. I hear how biologics help people, but I remain unconvinced."

4 / 10
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29 Report

Frequently asked questions

  • Kat...
  • Taken for 6 months to 1 year
  • June 16, 2019

For Ulcerative Colitis "I have had UC for over 10 years. Was taking Asacol, which worked for years, then stopped working. I have been on Entyvio for 6 months. It has helped my UC, but after a couple months of treatment, my knees were swelling. I am having so much pain in my knees now, I have trouble walking. I am stopping Entyvio, it’s not worth crippling myself."

3 / 10
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24 Report
  • All...
  • Taken for 2 to 5 years
  • May 20, 2019

For Ulcerative Colitis "Have been on vedolizumab for over 2 years now, and it has been amazing at eliminating all gut-related symptoms (I have Ulcerative Colitis). But over the 6 months or so, though, I've been experiencing weird and horrendous neurological symptoms: tingling, crawling, and burning, as well as pain and weakness. Seriously considering trying a new drug."

6 / 10
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19 Report

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  • Cas...
  • November 13, 2015

For Crohn's Disease "I have not been on it long enough. But it did control my diarrhea, not the pain. I was told because of my new diagnosis of Irritable Bowel Syndrome along with Crohn's Disease, they are stopping the infusions to see if the pain is not a side effect from it. This is all I know about it so far. I hope this helps a little."

8 / 10
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25 Report
  • Tra...
  • Taken for 1 to 2 years
  • September 9, 2023

"Entyvio has changed my life, so please understand that any of my side effects or experiences are 100% worth it for me. I have had this disease my whole life. I was finally diagnosed at 25. I’ve had on-and-off bouts of active, severe disease and long stretches of remission. In 2021, I had the absolute worst flare of disease in my life. I was severely anemic, I could not function due to weakness, diarrhea, and pain. I’m 55 and work hard to not let my health rule my life, but I felt like I was dying. I didn’t want to start a med like Entyvio because I figured I would need to stay on it forever if I did. I had some long conversations and decided it was the best option. I hate the steroids, and I was really too sick to decline the new meds. Within three infusions, I was so much better. I have continued to improve. My side effects are this: flushed skin and rash 1-2 hours after my appointment, I take Benadryl. Headache, body pain, gas, bloating, exhaustion for 48 hours. Entirely worth it."

9 / 10
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  • Joe...
  • March 13, 2018

For Ulcerative Colitis "I have tried almost every medicine there is, even Entyvio, but one medicine that I guarantee will help you is taking Suboxone. Please take my advice when you have a whole film of Suboxone, cut them into 4 slices, take just a quarter. I guarantee you that the diarrhea, the pains, and everything else will go away. Suboxone for ulcerative colitis has been a miracle drug for me and has helped me be in remission for about 4 years. Now I had it when I was 23, I took Suboxone at the age of 24, and I have been amazed. Suboxone is used to treat people with addiction, but it can be a miracle drug for other sicknesses. Please take my advice and at least give it a try, I promise you it will work better than any drug. The doctors have no idea what works because they are not rocket scientists and they don't have what we have. We, on the other hand, know what works and what doesn't."

3 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.