Lubiprostone Alternatives Compared
| Lubiprostone | Trulance (plecanatide) | Linzess (linaclotide) |
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| Lubiprostone | Trulance (plecanatide) | Linzess (linaclotide) |
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Prescription only
Prescribed for Irritable Bowel Syndrome with Constipation, Chronic Idiopathic Constipation, Opioid-Induced Constipation, Constipation, Irritable Bowel Syndrome. Lubiprostone may also be used for... View more |
Prescription only
Prescribed for Chronic Idiopathic Constipation, Irritable Bowel Syndrome with Constipation. Trulance may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Idiopathic Constipation, Irritable Bowel Syndrome with Constipation, Functional Constipation, Irritable Bowel Syndrome. Linzess may also be used for purposes not listed in this... View more |
Related suggestions Chronic Idiopathic Constipation
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| More about Lubiprostone | More about Trulance (plecanatide) | More about Linzess (linaclotide) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Lubiprostone has an average rating of 5.6 out of 10 from a total of 281 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 38% reported a negative effect. |
Trulance has an average rating of 6.1 out of 10 from a total of 279 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
Linzess has an average rating of 6.7 out of 10 from a total of 888 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Lubiprostone side effects |
View all Trulance side effects |
View all Linzess side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Lubiprostone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Linzess prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Amitiza |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 1 drugs are known to interact with Lubiprostone:
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A total of 1 drugs are known to interact with Trulance:
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A total of 60 drugs are known to interact with Linzess:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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January 31, 2006 |
January 19, 2017 |
August 30, 2012 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.