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Comparing Loperamide vs Sulfasalazine

Loperamide

Sulfasalazine

Loperamide effectively treats diarrhea by slowing down the movement of the bowel. In some people it may cause drowsiness. Prescribed for Traveler's Diarrhea, Diarrhea - Chronic, Diarrhea - Acute,... more

Prescribed for Rheumatoid Arthritis, Inflammatory Bowel Disease, Ulcerative Colitis, Juvenile Rheumatoid Arthritis, Lymphocytic Colitis, Ulcerative Colitis - Active, Ulcerative Colitis - Maintenance.... more

Prescription and OTC

Prescription only

Ratings & Reviews

Recent helpful reviews
8.6
42 Reviews

For Diarrhea Binds you up well, poo real nice and solid after, good to handle the squirts

10
Assman6969

For Diarrhea Wonder drug for Irritable Bowel Syndrome sufferers. I use it as a preventative and am able to live a normal life.

10
Anonymous
5.8
72 Reviews

For Rheumatoid Arthritis Rheumatoid arthritis since 1994, pretty severe case. Had to stop taking Humira and methotrexate due to repeated bouts with pneumonia and lung damage. Currently on sulfasalazine, Plaquenil and prednisone. Occasional flares but things are basically back under control.

6
SGM

For Rheumatoid Arthritis I have been on these meds for 6 weeks now. Started with one pill a day, then increased weekly to four pills a day. It has greatly helped with my pain. I'm sleeping better at night and especially within the last week, have been able to go about life almost how I did prediagnosis. So for that part - I would recommend giving it a go. As for side effects, I've been fortunate enough to not experience any type of stomach upset or headaches or anything like that. I have however been losing alot of hair. I can run my hand through very lightly, no tugging whatsoever, and end up with about 20 strands. I can run my hand through continually like this and the same thing happens. No pain from pulling, just falling out :( Choosing to tough it out for now

6
australiankitten

View all 42 reviews

View all 72 reviews

Drug Class

Side Effects

See the full loperamide side effects document.

Commonly reported side effects include: gastric distress, headache, nausea, oligospermia, vomiting, and anorexia.

See the full sulfasalazine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 6 capsule
Dosage 2 mg
Per Unit* $1.61
Cost* $9.67
View all loperamide prices
Quantity 50 each
Dosage 500 mg
Per Unit* $0.36
Cost* $17.84
View all sulfasalazine prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Oral capsule
  • Oral liquid
  • Oral suspension
  • Oral tablet
  • Oral delayed release tablet
  • Oral tablet

Brand Names
A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Imotil, Kao-Paverin,... more Azulfidine, Azulfidine EN-tabs, and Sulfazine

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

10.8 hours

10 hours

CSA Schedule

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

N/A

Drug Interactions

A total of 625 drugs are known to interact with loperamide:

  • 57 major drug interactions (207 brand and generic names)
  • 567 moderate drug interactions (3583 brand and generic names)
  • 1 minor drug interactions (7 brand and generic names)

A total of 308 drugs are known to interact with sulfasalazine:

  • 61 major drug interactions (275 brand and generic names)
  • 226 moderate drug interactions (1105 brand and generic names)
  • 21 minor drug interactions (102 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of loperamide such as dizziness, drowsiness,... more

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.

Disease Interactions

First Approval Date

December 28, 1976

June 20, 1950

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.

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