Comparing Lamotrigine vs Sertraline

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Lamotrigine Remove Lamotrigine from your drug comparison	Sertraline Remove Sertraline from your drug comparison	Add another drug to compare

Lamotrigine

Sertraline

Lamotrigine may be used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, lamotrigine may cause a potentially fatal... View more

Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Panic Disorder, Obsessive Compulsive Disorder, Major Depressive Disorder... View more

Prescription only

Ratings & Reviews

View all 1449 reviews

View all 3661 reviews

Drug Class

Triazine anticonvulsants

Selective serotonin reuptake inhibitors

Side Effects

Commonly reported side effects include: ataxia, skin rash, headache, insomnia, and nausea.

See the full lamotrigine side effects document.

Commonly reported side effects include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia.

See the full sertraline side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	100 each
Dosage	100 mg
Per Unit^*	$0.21
Cost^*	$21.13

View all lamotrigine prices

Quantity	100 each
Dosage	100 mg
Per Unit^*	$0.47 - $0.48
Cost^*	$46.68 - $47.84

View all sertraline prices

Get free Discount Card

Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral tablet
Oral tablet, disintegrating
Oral tablet, dispersible
Oral tablet, extended release

Oral concentrate
Oral tablet

Brand Names

Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite Zercapli, Zoloft

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

25.7 hours

66 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 265 drugs are known to interact with lamotrigine:

7 major drug interactions (26 brand and generic names)
246 moderate drug interactions (1727 brand and generic names)
12 minor drug interactions (45 brand and generic names)

A total of 624 drugs are known to interact with sertraline:

143 major drug interactions (564 brand and generic names)
474 moderate drug interactions (1948 brand and generic names)
7 minor drug interactions (35 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of lamoTRIgine such as dizziness, drowsiness... View more

You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can... View more

Disease Interactions

First Approval Date

December 27, 1994

December 30, 1991

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer