Comparing Kerendia vs Spironolactone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Kerendia (finerenone)	Spironolactone	Enter another drug to compare

Kerendia (finerenone)

Spironolactone

Prescription only

Prescribed for Chronic Kidney Disease. Kerendia may also be used for purposes not listed in this medication guide.

Prescription only

Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more

More about Kerendia (finerenone)

More about Spironolactone

Ratings & Reviews

Kerendia has an average rating of 8.3 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 0% reported a negative effect.

Spironolactone has an average rating of 6.9 out of 10 from a total of 703 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 3 reviews

View all 703 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Kerendia side effects

Acne (11.4%)
Dizziness (8.0%)
Hair loss (7.1%)
Weight gain (5.5%)
Headaches (5.1%)
Tiredness (4.4%)
Fatigue (4.3%)

View all Spironolactone side effects

Drug Class

Aldosterone receptor antagonists

Generic Availability

No lower cost generic approved

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 tablet
Strength	10 mg
Per unit^*	$24.77
Cost^*	$743.07

View all Kerendia prices

Quantity	100 each
Strength	25 mg
Per unit^*	$0.23 - $0.25
Cost^*	$23.10 - $25.17

View all Spironolactone prices

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Dosage Forms

Oral tablet

Oral suspension
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

3 hours

37 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 332 drugs are known to interact with Kerendia:

121 major drug interactions (455 brand and generic names)
210 moderate drug interactions (645 brand and generic names)
1 minor drug interactions (2 brand and generic names)

A total of 382 drugs are known to interact with Spironolactone:

51 major drug interactions (248 brand and generic names)
311 moderate drug interactions (1490 brand and generic names)
20 minor drug interactions (145 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Finerenone may be taken with or without food. However, you should avoid grapefruit and grapefruit... View more

Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may... View more

Disease Interactions

First Approval Date

July 09, 2021

January 21, 1960

WADA Class View classifications

N/A

S5 - Diuretics and Other Masking Agents

More Information

Patient Resources

Kerendia uses

Spironolactone uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Kerendia vs Spironolactone

See also:

Jardiance

Farxiga

Ozempic

Lasix

Rybelsus

Wegovy

Furoscix

Inpefa

Demadex

Soaanz

Further information

Comparing Kerendia vs Spironolactone

See also:

Further information

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