Fentanyl Alternatives Compared
| Fentanyl | Tramadol | Gabapentin |
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| Fentanyl | Tramadol | Gabapentin |
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Fentanyl is a very potent pain-relieving medicine. It is not recommended for people who have never been prescribed opioid-type pain relief before, and deaths have been reported from improper dosing... View more |
Tramadol is a strong pain relief medicine effective for both general and nerve-related pain. Tramadol can cause dependence and use may be limited by side effects such as nausea and... View more |
Gabapentin may be used in the treatment of partial-onset seizures and nerve pain but is likely to cause dizziness or drowsiness. Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin... View more |
Choose a suggestion below |
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| More about Fentanyl | More about Tramadol | More about Gabapentin | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Fentanyl has an average rating of 7.9 out of 10 from a total of 408 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 10% reported a negative effect. |
Tramadol has an average rating of 6.8 out of 10 from a total of 1714 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 25% reported a negative effect. |
Gabapentin has an average rating of 7.1 out of 10 from a total of 2312 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: fever, respiratory depression, nausea, vomiting, diaphoresis. See the full fentanyl side effects document. |
Commonly reported side effects include: pruritus, agitation, anxiety, constipation, diarrhea, hallucination, nausea, tremor, vomiting, diaphoresis. See the full tramadol side effects document. |
Commonly reported side effects include: ataxia, dizziness, drowsiness, fatigue, fever, nystagmus disorder, sedated state, viral infection. See the full gabapentin side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all fentanyl prices |
View all tramadol prices |
View all gabapentin prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Actiq, Duragesic, Fentanyl Transdermal System, Fentora, Lazanda, Subsys | ConZip, Qdolo, Tramadol Hydrochloride ER, Ultram | Fanatrex, Gabarone, Gralise, Neurontin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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8.7 hours |
5.2 hours |
6 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 563 drugs are known to interact with fentanyl:
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A total of 637 drugs are known to interact with tramadol:
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A total of 264 drugs are known to interact with gabapentin:
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| First Approval Date | ||||||||||||||||||||||||||
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February 19, 1968 |
March 03, 1995 |
December 30, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.