Comparing Fentanyl vs Hydromorphone
| Fentanyl | Hydromorphone |
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| Fentanyl | Hydromorphone |
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Prescription only
Fentanyl is a very potent pain-relieving medicine. It is not recommended for people who have never been prescribed opioid-type pain relief before, and deaths have been reported from improper dosing... View more |
Prescription only
Hydromorphone is a morphine-like pain-relieving medicine that may be given to relieve severe pain that is not relieved by other pain-relieving treatments. It carries a high risk of respiratory... View more |
Related suggestions Anesthetic Adjunct
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| More about Fentanyl | More about Hydromorphone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Fentanyl has an average rating of 7.8 out of 10 from a total of 433 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 11% reported a negative effect. |
Hydromorphone has an average rating of 8.0 out of 10 from a total of 449 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Fentanyl side effects |
View all Hydromorphone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Fentanyl prices |
View all Hydromorphone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Actiq, Duragesic, Fentanyl Transdermal System, Fentora, Lazanda, Subsys | Dilaudid | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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8.7 hours |
3.1 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 633 drugs are known to interact with Fentanyl:
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A total of 439 drugs are known to interact with Hydromorphone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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February 19, 1968 |
December 07, 1992 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.