Comparing Fentanyl vs Hydromorphone
| Fentanyl | Hydromorphone |
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| Fentanyl | Hydromorphone |
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Prescription only
Fentanyl is a very potent pain-relieving medicine. It is not recommended for people who have never been prescribed opioid-type pain relief before, and deaths have been reported from improper dosing... View more |
Prescription only
Hydromorphone is a morphine-like pain-relieving medicine that may be given to relieve severe pain that is not relieved by other pain-relieving treatments. It carries a high risk of respiratory... View more |
Related suggestions Anesthetic Adjunct
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| More about Fentanyl | More about Hydromorphone | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Fentanyl has an average rating of 7.9 out of 10 from a total of 418 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 11% reported a negative effect. |
Hydromorphone has an average rating of 8.0 out of 10 from a total of 439 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: fentanyl side effects in more detail. |
See also: hydromorphone side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all fentanyl prices |
View all hydromorphone prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Actiq, Duragesic, Fentanyl Transdermal System, Fentora, Lazanda, Subsys | Dilaudid | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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8.7 hours |
3.1 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 574 drugs are known to interact with fentanyl:
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A total of 407 drugs are known to interact with hydromorphone:
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| First Approval Date | |||||||||||||||||
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February 19, 1968 |
December 07, 1992 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.