Excedrin Alternatives Compared
Excedrin | Sumatriptan | Imitrex |
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Excedrin (acetaminophen / aspirin / caffeine) | Sumatriptan | Imitrex (sumatriptan) |
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Over-the-counter
Prescribed for Migraine, Pain/Fever, Osteoarthritis. Excedrin may also be used for purposes not listed in this medication guide. |
Prescription only
Sumatriptan may be used to quickly relieve the symptoms of a migraine but may not be suitable for everyone including those with pre-existing cardiovascular conditions. Prescribed for Cluster... View more |
Prescription only
Prescribed for Cluster Headaches, Migraine. Imitrex may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Excedrin (acetaminophen / aspirin / caffeine) | More about Sumatriptan | More about Imitrex (sumatriptan) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Excedrin has an average rating of 7.1 out of 10 from a total of 39 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 31% reported a negative effect. |
Sumatriptan has an average rating of 7.7 out of 10 from a total of 547 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 16% reported a negative effect. |
Imitrex has an average rating of 7.8 out of 10 from a total of 206 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: Excedrin side effects in more detail. |
See also: sumatriptan side effects in more detail. |
See also: Imitrex side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all sumatriptan prices |
View all Imitrex prices |
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Dosage Forms Available | ||||||||||||||||||
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Brand Names | ||||||||||||||||||
Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more | Imitrex, Imitrex Nasal, Imitrex Statdose, Onzetra Xsail, Tosymra, Zembrace SymTouch | Other sumatriptan brands include: Imitrex Nasal, Imitrex Statdose, Onzetra Xsail, Tosymra, Zembrace SymTouch | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
10 hours |
6 hours |
6 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 531 drugs are known to interact with Excedrin:
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A total of 99 drugs are known to interact with sumatriptan:
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A total of 99 drugs are known to interact with Imitrex:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
N/A |
January 28, 2016 |
June 01, 1995 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
N/A |
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Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.