Excedrin Alternatives Compared
| Excedrin | Nurtec ODT | Botox |
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| Excedrin (acetaminophen / aspirin / caffeine) | Nurtec ODT (rimegepant) | Botox (onabotulinumtoxinA) |
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Over-the-counter
Prescribed for Migraine, Osteoarthritis, Pain/Fever. Excedrin may also be used for purposes not listed in this medication guide. |
Prescription only
Nurtec ODT may be placed onto or under the tongue to treat the symptoms of migraine in adults, and it may also be used to prevent episodic migraine when taken every second day. Nurtec ODT works by... View more |
Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Related suggestions |
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| More about Excedrin (acetaminophen / aspirin / caffeine) | More about Nurtec ODT (rimegepant) | More about Botox (onabotulinumtoxinA) | ||||||||||||||||
| Generic Status | ||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||
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Excedrin has an average rating of 7.0 out of 10 from a total of 38 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 31% reported a negative effect. |
Nurtec ODT has an average rating of 5.3 out of 10 from a total of 201 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 43% reported a negative effect. |
Botox has an average rating of 5.5 out of 10 from a total of 440 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 43% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: Excedrin side effects in more detail. |
See also: Nurtec ODT side effects in more detail. |
Common side effects include:
See also: Botox side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Nurtec ODT prices |
View all Botox prices |
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| Dosage Form(s) Available | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more |
N/A |
Other onabotulinumtoxinA brands include: Botox Cosmetic | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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10 hours |
11 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 448 drugs are known to interact with Excedrin:
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A total of 141 drugs are known to interact with Nurtec ODT:
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A total of 114 drugs are known to interact with Botox:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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| First Approval Date | ||||||||||||||||||
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N/A |
February 27, 2020 |
December 09, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| Patient resources | ||||||||||||||||||
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N/A |
N/A |
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| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.