Comparing Eplerenone vs Furosemide

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Eplerenone	Furosemide	Enter another drug to compare

Eplerenone

Furosemide

Prescription only

Prescribed for Heart Failure, High Blood Pressure. Eplerenone may also be used for purposes not listed in this medication guide.

Prescription only

Furosemide significantly increases urination which relieves excess fluid, but its use may also lead to the depletion of certain electrolytes in the body (such as potassium). Prescribed for Edema... View more

More about Eplerenone

More about Furosemide

Ratings & Reviews

Eplerenone has an average rating of 4.9 out of 10 from a total of 14 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 50% reported a negative effect.

Furosemide has an average rating of 6.8 out of 10 from a total of 121 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 21% reported a negative effect.

View all 14 reviews

View all 121 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Eplerenone side effects

Swelling (15.7%)
Frequent urination (7.4%)
Headaches (5.8%)
Cramps (3.3%)
Blood pressure (2.5%)
Confusion (2.5%)
Nausea (2.5%)

View all Furosemide side effects

Drug Class

Loop diuretics

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	25 mg
Per unit^*	$3.83
Cost^*	$115.00

View all Eplerenone prices

Quantity	1 tablet
Strength	20 mg
Per unit^*	$10.07
Cost^*	$10.07

View all Furosemide prices

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Dosage Forms

Oral tablet

Injectable solution
Oral liquid
Oral solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

1.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 414 drugs are known to interact with Eplerenone:

76 major drug interactions (311 brand and generic names)
322 moderate drug interactions (1445 brand and generic names)
16 minor drug interactions (51 brand and generic names)

A total of 508 drugs are known to interact with Furosemide:

26 major drug interactions (78 brand and generic names)
460 moderate drug interactions (2085 brand and generic names)
22 minor drug interactions (96 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be... View more
Eplerenone and alcohol may have additive effects in lowering your blood pressure. You may... View more

Furosemide and alcohol may have additive effects in lowering your blood pressure. You may... View more

Disease Interactions

First Approval Date

September 27, 2002

July 01, 1966

WADA Class View classifications

N/A

S5 - Diuretics and Other Masking Agents

More Information

Patient Resources

Furosemide uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Eplerenone vs Furosemide

See also:

Jardiance

Farxiga

Ozempic

Lasix

Entresto

Coreg

Norvasc

Aldactone

Coumadin

Toprol-XL

Further information

Comparing Eplerenone vs Furosemide

See also:

Further information

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