Effexor Alternatives Compared
| Effexor | Bupropion | Cymbalta |
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| Effexor (venlafaxine) | Bupropion | Cymbalta (duloxetine) |
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Prescription only
Effexor is an antidepressant that may cause a discontinuation syndrome if abruptly stopped after long-term administration. Prescribed for Autism, Major Depressive Disorder, Depression, Bulimia... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about (venlafaxine) | More about Bupropion | More about Cymbalta (duloxetine) | ||||||||||||||||
| Generic Status | ||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Effexor has an average rating of 5.8 out of 10 from a total of 483 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 33% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2729 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 21% reported a negative effect. |
Cymbalta has an average rating of 6.2 out of 10 from a total of 1814 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: Effexor side effects in more detail. |
Commonly reported side effects include:
See also: bupropion side effects in more detail. |
Common side effects include:
See also: Cymbalta side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all bupropion prices |
View all Cymbalta prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other venlafaxine brands include: Effexor XR | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other duloxetine brands include: Drizalma Sprinkle, Irenka | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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4 hours |
30 hours |
17 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 663 drugs are known to interact with Effexor:
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A total of 484 drugs are known to interact with bupropion:
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A total of 576 drugs are known to interact with Cymbalta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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N/A |
December 30, 1985 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.