Comparing Duloxetine vs Zoloft

For Depression: I am taking duloxetine, just had a horrific experience with the generic manufacture Solco. I have taken 4 different manufacture versions in 3 different dosages since June 2017. First day talking a Solco pill I had depressive episode, woke up next morning and had a panic attack. Crying, severe headache on right side, unconscious arm and leg twitching, inability to control my voice volume, loss of coordination. It was as if I suddenly reversed what remission I had achieved and broke through to a whole new ultra low. This went on 4 days before I suspected my meds. Went to ER because I thought I might be dying. Walgreens doesn't want to stock Tevas pills, and CVS has to special order them too, leaving me with a different manufacture and dosage combination again. I was really excited to feel good again, but I had to crawl back to start over a proprietary formula and delivery method that has no published science available to the public. I will report this to the FDA.

For Depression: Been taking generic cymbalta for about 2 months for depression, anxiety, and OCD. When I first started I fluctuated between super tired and super hyper, that lasted for a few weeks. I also got dizzy a lot. After about 4 weeks all the side effects went away and now it's helping a lot with depression and helps a bit with anxiety and OCD. Your mileage may vary but for me this medication has been a godsend.

For Depression: Just take these reviews with a grain of salt. A lot of reviews after taking one day, couple weeks etc. you need a full three months for maximum effectiveness. Not that it takes that long to start getting relief. Side effects are common while your body adjusts. Some of them will go away. I had no troublesome side effects with Zoloft. I always have to start out gradually. Maybe even more than they say bc I’m sensitive to meds. I got big relief from depression. Panic attacks went away. OCD went away. The cons are it made me not very motivated, felt kind of numb to strong feelings. Not feeling urgency about my life. I wouldn’t take it again for years bc it blocked my clear perspective. But it was great to get me stabilized. Things that really help but can’t completely replace anti dep is fish oil, vit d, exercise, sunlight, folate like spinach , lentils really good. Also diet really helps. Get a book called the good mood diet. Best wishes

For Depression: I'm a 31 year old Male who has had challenges with depression and anxiety throughout my life. I have been on several different meds in my past, including lexapro, paxil, effexor, wellbutrin, prozac, zoloft, and some others as well. Of all of these meds, I've found zoloft works the best for me. However the worst thing I experience with zoloft is decreased libido, as with all of the other meds I've tried, except for wellbutrin. This side effect truly sucks. Zoloft also kind of makes me feel robotic and emotionally numb. Currently I'm experimenting with another medication (viibryd) in attempt to find a med that works without having sexual side effects. However zoloft is my fallback option, because this med at least stabilizes me and helps function in society. Therefore I give this med a 7 out of 10. My advice to everyone is to keep being patient with meds and realize that it might take some time and trial and error. And always keep hanging in there no matter what. Good luck.