Comparing Dextromethorphan vs Promethazine
| Dextromethorphan | Promethazine |
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| Dextromethorphan | Promethazine |
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Prescription and OTC
Prescribed for Cough. Dextromethorphan may also be used for purposes not listed in this medication guide. |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
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| More about Dextromethorphan | More about Promethazine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dextromethorphan has an average rating of 3.7 out of 10 from a total of 388 ratings on Drugs.com. 20% of reviewers reported a positive effect, while 62% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 392 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Dextromethorphan side effects |
View all Promethazine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dextromethorphan prices |
View all Promethazine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| 12 Hour Cough Relief, Babee Cof, Balminil DM, Benadryl for the Family Dry Forte, Benylin DM, Bisolvon Dry, Bisolvon Dry Junior, Buckley's DM, Buckley's Mixture Cough Suppressant, Buckleys Mixture, Calmylin, Contac Cough, Cough Syrup DM, Covonia Bronchial Balsam, Creomulsion, Creomulsion Children, Delsym, Delsym 12 Hour Cough Relief, Delsym 12 Hour Cough Relief for Children & Adults, Delsym Children's 12-Hour Cough Relief, DexAlone, Dexi-Tuss, Dextromethorphan HBr Adult Formula, Dristan DM, Dry Cough, Duract Max Strength Cough, ElixSure Cough, Giltuss Children's Honey DM 8hr Cough, Giltuss Honey DM 8hr Cough, Hold, Hold DM, Robafen Cough Liquidgels, Robitussin 12-Hour Cough Relief, Robitussin Children's Cough Long-Acting, Robitussin Cough Long-Acting, Robitussin CoughGels Long-Acting, Robitussin Direct Cough, Scot-Tussin Diabetes, Silphen DM, Sucrets Cough, Triaminic Long Acting Cough, Triaminic Thin Strips Cough, Tussin Cough Gels (Long Acting), Vicks Dayquil Cough, Vicks Formula 44, Vicks Formula 44 Custom Care Dry Cough Suppressant, Vicks Nature Fusion Cough View more | Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.6 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 369 drugs are known to interact with Dextromethorphan:
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A total of 689 drugs are known to interact with Promethazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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October 08, 1982 |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Norco
Norco (acetaminophen and hydrocodone) is used to relieve moderate to severe pain. Includes Norco ...
Dilaudid
Dilaudid (hydromorphone) is a narcotic pain reliever used to treat moderate to severe pain ...
Vicodin
Vicodin (acetaminophen and hydrocodone) is used to relieve moderate to severe pain. Includes ...
Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.