Depakote ER Alternatives Compared
| Depakote ER | Lamictal | Lamotrigine |
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| Depakote ER (divalproex sodium) | Lamictal (lamotrigine) | Lamotrigine |
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Prescription only
Prescribed for Bipolar Disorder, Mania, Epilepsy, Migraine Prevention. Depakote ER may also be used for purposes not listed in this medication guide. |
Prescription only
Lamictal is used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, Lamictal may cause a potentially fatal rash... View more |
Prescription only
Lamotrigine may be used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, lamotrigine may cause a potentially fatal... View more |
Related suggestions |
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| More about Depakote ER (divalproex sodium) | More about Lamictal (lamotrigine) | More about Lamotrigine | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Depakote ER has an average rating of 7.4 out of 10 from a total of 96 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 12% reported a negative effect. |
Lamictal has an average rating of 7.9 out of 10 from a total of 723 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 14% reported a negative effect. |
Lamotrigine has an average rating of 7.7 out of 10 from a total of 1654 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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Common side effects include:
See also: Depakote ER side effects in more detail. |
Common side effects include:
See also: Lamictal side effects in more detail. |
Commonly reported side effects include:
See also: lamotrigine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Depakote ER prices and generic prices |
View all Lamictal prices and generic prices |
View all lamotrigine prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other divalproex sodium brands include: Depakote, Depakote Sprinkles | Other lamotrigine brands include: Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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16 hours |
25.7 hours |
25.7 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 378 drugs are known to interact with Depakote ER:
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A total of 282 drugs are known to interact with Lamictal:
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A total of 282 drugs are known to interact with lamotrigine:
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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N/A |
N/A |
December 26, 2012 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.