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User Reviews for Depakote ER

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Epilepsy 15 reviews 40 medications
   
7.9
Mania 3 reviews 14 medications
   
7.8
Bipolar Disorder 26 reviews 33 medications
   
7.5
Migraine Prevention 21 reviews 30 medications
   
7.4
Summary of Depakote ER reviews 65 reviews 7.7

Reviews for Depakote ER

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For Epilepsy "Insurance covers generic only. The generic medication changes from manufacture to manufacture, the different brand changes from month to month can lead to breakthrough seizures. In order to prevent that I must either pay out of pocket about $450 or find a generic about $10 that works. I found one generic that works well and go from pharmacy to pharmacy tracking that one down."

   
9.0

rainysunnywind888 November 3, 2016

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For Bipolar Disorder "I was suffering from bipolar for 10 months. After taking many medicines i was on divalproex 500 mg for 3 years and lamotrigine 150mg for 2 years. I was able to handle stress and forget that i have any depression. My dosage for both was kept to lowest 250 mg for divalproex and 50 mg for lamotrigine. But on this stage after having stress my symptoms reuccured but was not severe as before. I will have too increase the dose again."

   
10

Huzaiff (taken for 2 to 5 years) September 5, 2016

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For Bipolar Disorder "After my first manic episode at 39, was hospitalized and chose Depakote over Risperdal due to weight gain fears. It's been 2 weeks and along with intensive therapy and healthy lifestyle it's definitely brought me back to reality"

   
7.0

Bipolar 1 recently diagnosed (taken for less than 1 month) July 19, 2016

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For Bipolar Disorder "I started taking Divalproex(Depakote)250mg on June 10th and than on June 17th I was admitted into a psychiatric hospital because of my bipolar. I learned from the psychiatrist there that the dosage I was on was absolutely nothing and would have no effect on me. The psychiatrist ended up raising the dose to 750mg. I definetly can tell that my mood is leveled out for the most part. I would recommended this to people with bipolar and people with seizures(I was diagnosed a few years ago with non eptiletic seizures). So far I dont see any side effects, thank God. I take this medication at night along with: Aripiprazole(Abilify)15mg Trazodone(Desyrel)50mg Hydroxyzine(Vistaril)50mg Clonazepam(Klonopin)1mg"

   
8.0

StayStrongJustBreath92 (taken for less than 1 month) June 25, 2016

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For Bipolar Disorder "I was treated for clinical depression from age 18-40 using a variety of medications. I've also struggled with alcoholism, drug and sex addiction most of my adult life. I had a period of six years' solid sobriety beginning in the mid 90's but, even sober, battled with diagnosed clinical depression. At that time I was being treated with Serzone. The more the doctor increased the dosage the more depressed I would become. I obsessed on failed relationships, acted out sexually and financially in very risky ways. I finally changed Psychiatrists at the suggestion of my Therapist. The new doctor analyzed my symptoms and indicated that I had been misdiagnosed with clinical depression. His prognosis was Bipolar II Disorder accompanied by acute depression"

   
5.0

NunyaSAT (taken for 10 years or more) May 30, 2016

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For Bipolar Disorder "I've been taking this for a few years and I have severe headaches often along with suffering with low back pain which is constant on my left side and nothing is soothing it. Laying down is excruciating and I'm in the process of running test. This started about 4 months ago and I have been trying to deal with it and hope that it would eventually go away. It's becoming unbearable."

   
4.0

Langelle23 (taken for 2 to 5 years) May 19, 2016

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For Bipolar Disorder "Depakote has worked great for me. It totally helps with mania. The only medication that clears up my head and makes me feel normal. Also it gets rid of my migranes. The only bad thing is a few side effects. I gained weight and my hair fell out. And I was pretty lathargic at first. Takes a while but once it kicks in I felt like a whole person. I was off of it for a long time and recently was put back on it so going through side effects again but felt a difference rite away."

   
9.0

jamel102065 (taken for less than 1 month) May 13, 2016

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For Bipolar Disorder "Honestly this medicine has saved my life! I went from having multiple long lasting episodes of mania to none. Ya i still get the thoughts but im relaxed and able to make conscious choices now that im on it. The only negative side affect is the hair loss but its temporary, but so worth it. Nothing is better than feeling like you are in control of yourself, and this medicine does this for you dont be scared to ask your doctor about it!"

   
10

Susyg (taken for 6 months to 1 year) April 27, 2016

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For Bipolar Disorder "Have been taking this med since 1992 w/ some breaks here and there. I too have been on, what would seem, every med for Bipolar diagnosis. I take 1750mg and also take 400mg of Lamictal (another mood stabilizer which seems to help with the depression) My only issue had been weight gain which remains a problem. 10 years stable, after being hospitalized for 8 months due to manic episode and psychotic break (was only taking Topamax at that time). Would highly recommend."

   
9.0

blessed5# March 11, 2016

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For Bipolar Disorder "This drug took me out of a downward spiraling mixed episode, for that I'm thankful. However, being BiPolar II, the initial dosage of 1750 mg. which was never recommended to lower after its effectiveness had been reached, almost put me right back to where I was. I wouldn't recommend this drug if you're on the depressive side of BiPolar, or for any length of time/dosage that the medication isn't even recommended to be used for. I've since switched to Lamictal, will see how it goes."

   
5.0

HappytoB (taken for 1 to 6 months) January 13, 2016

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For Migraine Prevention "I was on Topimax 1000mg a day for approximately 10 years. Yes, I experienced the side effects of tingling in my fingers & toes sporadically. Had a migraine maybe 1 time/year (prior I had 2 migraines a week) Finally, the Topimax became ineffective (body probably was immune) and switched to Depakote 250 mg a day (125 mg in the morning and 125 mg at bedtime). No headache! I did gain 15-20 pounds in the first 3 months- I was well aware of the possible weight gain. Weight gain is well worth it - when the alternative is migraines. Have to weigh pro's & con's. Also I take OTC 5-HTP to combat the fuzziness and such. Can't complain...."

   
9.0

Happy to report no headache December 10, 2015

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For Bipolar Disorder "I've been taking Depakote ER 500mg at night for 2wks now. I'm Bipolar 1. It's amazing! I've slept great! No side effects. No mood swings. I feel very balanced. I've taken many psych meds over the past 13 yrs. Finally! The right med! I say. Give it a chance if U suffer from severe Bipolar, mood swings, anxiety/panic attacks, sleep disorder...etc. This is working. People close 2 me say I'm a lot calmer now. More rational. Were as b4 I'd quickly lash out! Not now."

Jamie STL (taken for less than 1 month) September 9, 2015

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For Bipolar Disorder "I took this at night per my doctor, and about the 3rd week I noticed a huge change in my energy and I started having severe muscle cramping and weakness. I woke up in the morning feeling beat up and muscle soreness everywhere. It didn't really help with my issue either. I stopped taking it, and 3 days later the muscle soreness was completely gone"

   
3.0

AlliGibby July 7, 2015

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For Bipolar Disorder "Very smooth mood stabilizer, no side effects. I take 1200 mg/d."

   
10

be2 (taken for 2 to 5 years) June 30, 2015

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For Migraine Prevention "I ben taking 1,000mg a day .I split up 500 in morning and 500 at night for 3 months. I gained 35pounds in the first month. Its a great mood stabilizer, but it only works part of the time. I have the shakes ,acne , vision problems from it. I took topimax before it was great but I got kidney stones from it . I need to get another med that actually works!"

   
4.0

d273 June 18, 2015

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For Bipolar Disorder "I had a strong desire to drive off of the road even with other people in the car. Otherwise this worked well but the desire increased the longer I was on it."

   
7.0

Corrie B May 24, 2015

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For Bipolar Disorder "I have been on Depakote ER for 4 months. My dosage is 1500mg a day. I went untreated for many years (18yrs) because I didn't have health care and failure to accept something was wrong even though I was a lot off the wall. After 3 weeks of Depakote my moods were pretty even and stable. I also felt a little numb, I missed my highs, but it was better than being psychotic one minute and crying in another. But at the 4 month mark my hair has started falling out in clumps, that was my only side effect. So I'm now transitioning to lithium. Fingers crossed."

   
9.0

SariahMc December 13, 2014

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For Bipolar Disorder "Crushed mania fast on 2000 mg/d and currentyl stable on this dose"

   
10

livelife52 October 13, 2014

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For Migraine Prevention "I have only been taking Depakote ER 500 mg for 10 days now, or maybe I should say nights. I take it at bed time, & was supposed to start taking it twice a day after a week but the upset stomach, the shakes, (or extra nervousness), no sign of relief of my migraines, & I haven't been able to sleep at night either.. I'm going to tell my Dr. that I just can't take it any more."

   
1.0

Cowboy 61 June 22, 2014

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For Bipolar Disorder "Had to take it in conjunction with Seroquel for it to work. Currently on 1g of Depakote ER per day and 50mg of Seroquel per night. With the two mood stabilizers, I am able to take 20mg of Dexedrine ER for my ADHD to focus on work/school without spinning myself into a hypomanic episode. Keep experimenting, until you find what works. I know it can be discouraging, but you'll get there eventually."

   
7.0

X21389 (taken for 1 to 6 months) April 20, 2014

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For Bipolar Disorder "Caused suicidal depression"

   
1.0

i2 (taken for 1 to 6 months) April 7, 2014

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For Migraine Prevention "After being on Depakote Er for 8 months, it was really effective in reducing the migraines. As side effects, I never gained one single pound, but the hair loss was just unbearable. I lost half of all my hair. I had to stop taking it, unfortunately. I have always had headaches, since I was a child. Before Depakote, I stayed one month having headaches every single day, had to stay in bed, couldn't even walk, and I felt like I reached the lowest point in my life, I wouldn't be able to live with the pain anymore, I had no life. After 2 weeks on Depakote er 500mg I started getting better. I was having only 8/10 per month. Now I'm on topiramate for 2 weeks, the hair is still falling a lot and the migraines are back, almost everyday."

   
8.0

PamelaCosta February 5, 2014

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For Epilepsy "51 yr old female, I've had seizures since I was 12, every kind, I was on every medicine under the sun. Taking Depakote ER and Carbatrol ER seems to be only meds that work for me. some side effects nothing I can't handle, better than having seizures all day. (tired, sometimes depressed, trembles, jerks). I have gran mal / tonic clonic about 1 every 10 years."

   
10

ved (taken for 10 years or more) October 18, 2013

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For Migraine Prevention "I've also been trying different preventive medication for migraines with my doctor and so far Depakote is working the best. I started with 250mg a day for the first week, now at 500 mg a day. Before this medication, I would wake up daily with chronic head pain in the neck or behind the eyes. Now I wake up almost every morning with a clear head. I haven't seen any side effects yet at this dosage and I've even lost weight since I've been proactive with daily exercise. I started walking 2 miles daily since taking this medication. With proactive exercise and eating habits, I think anyone can keep potential side effects at bay. Previously, I was on Topamax and had to stop taking it as the nausea/head fuzz was too severe for my line of work."

   
9.0

Toban M October 15, 2013

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For Bipolar Disorder "This medicine has been great for me. I do not feel any side effects. I actually lost 25 pounds... I had been on lithium for 28 years."

   
10

Anita Key (taken for 5 to 10 years) August 24, 2013

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