Depakote ER and Fatigue: What Users Say

• Moo...
• Taken for less than 1 month
• October 9, 2019

For Bipolar Disorder "I must start off by saying everyone is different and will react differently. My condition is unofficially diagnosed. But I was told when I was a teenager I was a manic depressive with a possible hormonal imbalance. Recently, I have had two major mania events: accelerated heart rate, palpitations, headaches, dizziness, fatigue, mood swings, confusion, and memory loss to name a few. The night I took this medication, I felt it kick in. I felt great and had so much mental energy I didn't have before. It has been working for me. I suggest eating when you take this medication, it can make you nauseous. I haven't seen any side effects other than that. Each to their own, though. Just wanted to post this to this forum to let you know if this doesn't work for you, there is a medication that will work. Don't give up!"

• Cha...
• May 21, 2013

For Migraine Prevention "Medication was very effective at controlling silent migraines, but long-term use (more than 10 years) has resulted in a 60-pound weight gain, hair loss, and shakiness. Recently, I have felt very fatigued and confused."

• gre...
• July 14, 2008

For Migraine Prevention "I have been on Depakote ER 1000 mg for 2 months, and it has almost solved my migraine problem. I still get a few slight nagging headaches, which are easy to treat with ibuprofen. The side effects of stomach upset and fatigue seem to be improving. I think I notice some weight gain, maybe too early to tell. So far, so good. I'm happy with this medication. My migraines were threatening my ability to earn a living, and many days were spent in bed. Things are looking up."

• Mys...
• Taken for 2 to 5 years
• February 21, 2021

For Bipolar Disorder "Thank you, Depakote ER, for giving me a new life. I take Prozac and Depakote ER for bipolar. It has been a long road to accepting the fatigue, but the dangerous, uneven life I used to live, I had to come to terms with it. I had horrible manic episodes on other medications that did not work. This combo is perfect, except the fatigue is the hardest part. But I don’t have to suffer like that. I have breakthrough episodes, but I can increase the Depa dose if needed. The only medicine that has changed me and allowed me to live a normal life."

• Anonymous
• February 10, 2009

For Epilepsy "I took the medication for two years as a teenager. It stopped the seizures, but I lost all my energy and put on 40 pounds. Once I stopped Depakote, I nearly lost all the weight within 2 months."