Comparing Climara vs Progesterone
| Climara (estradiol) | Progesterone |
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| Climara (estradiol) | Progesterone |
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Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Oophorectomy, Hypoestrogenism, Prevention of Osteoporosis, Primary Ovarian Failure. Climara may also be used for... View more |
Prescription and OTC
Progesterone is used to prevent endometrial hyperplasia in postmenopausal women with a uterus who are receiving estrogen tablets. It is also used to treat secondary amenorrhea. Common side effects... View more |
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| More about Climara (estradiol) | More about Progesterone | ||||||||
| Ratings & Reviews | |||||||||
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Climara has an average rating of 6.3 out of 10 from a total of 62 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect. |
Progesterone has an average rating of 6.5 out of 10 from a total of 78 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Climara side effects |
View all Progesterone side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Progesterone prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other estradiol brands include: Alora, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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16 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 393 drugs are known to interact with Climara:
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A total of 222 drugs are known to interact with Progesterone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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December 22, 1994 |
November 01, 1974 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.