Amoxapine Alternatives Compared
| Amoxapine | Bupropion | Sertraline |
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| Amoxapine | Bupropion | Sertraline |
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Prescription only
Prescribed for Depression. Amoxapine may also be used for purposes not listed in this medication guide. |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Depression
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| More about Amoxapine | More about Bupropion | More about Sertraline | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Amoxapine has an average rating of 9.8 out of 10 from a total of 5 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Bupropion has an average rating of 7.1 out of 10 from a total of 2898 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4550 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Amoxapine prices |
View all Bupropion prices |
View all Sertraline prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Zoloft | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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8 hours |
30 hours |
66 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 691 drugs are known to interact with Amoxapine:
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A total of 526 drugs are known to interact with Bupropion:
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A total of 672 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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September 22, 1980 |
December 30, 1985 |
December 30, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.