Trintellix for Major Depressive Disorder User Reviews (Page 3)

• Lilmi...
• Taken for 1 to 6 months
• September 3, 2018

"I've been diagnosed with double depression which is a combo of persistent depressive disorder and major depression and I've been on so many medications that this need was my last shot before ECT. I can't believe the difference trintellix has made in my life. I no longer have to worry about ECT and I feel good for the first time in 17 years."

• Lovel...
• Taken for 1 to 6 months
• May 19, 2017

"I was diagnosed with major depression after years of dealing with terrible Rheumatoid arthritis that has limited my mobility. My doctor prescribed me 3 different antidepressants and after Cymbalta gave me head zaps and my anxiety was causing panic attacks he switched me to Trintellix. I started on the 5 mg while I was weaning off 60 mgs of Cymbalta. The nausea was so bad. I would like to think I have a pretty strong stomach but this med made me sick like when I was pregnant. I stuck with it and 3 weeks in at 10 mgs I feel fantastic! I'm so glad I stuck with it!! I'm laughing again and my motivation is incredible! It was so worth it! If you're debating it stick with it through the nausea to see if it works for you. Im truly thankful!!"

• Beanah
• June 19, 2016

"Have Major Depressive Disorder & PTSD. MAJOR ANXIETY DAILY. LIFE WAS UNBAREABLE. Brintellix 10mg has been a miracle for me. Haven't had suicidal thoughts, I'm able to work again.. I can feel the real, happy me. I've also tried many other "anti depressants" that didnt work well for me. THIS! by FAR, is the best. Worked quickly too. Good luck to all. Also I am blessed to have the prescriber I do who specializes in PTSD."

• Happy
• Taken for less than 1 month
• January 9, 2018

"This medication has changed my life. For me the cons are: I have energy to go, go, go which I have never had, I feel happy for the first time ever, my panic attacks have completely stopped, I look forward to my future, I am so calm with everyone where I was being very hateful and snappy before, and I am no long afraid everyone is watching me every time I go in any public setting. I have not experienced any side effects. If you need a motivating, calming, make you feel happy med I suggest trintellix. Diagnosis: PTSD, Major Depression disorder, borderline personality disorder, OCD, and anxiety."

• Mike...
• September 20, 2016

"This medication has helped me so much! I tried Prozac, Zoloft, and Lexapro before starting this medication. I felt much better in about 3 days with Trintellix. It is so nice to have more focused energy and be able to function again at work as well as having fun with my kids again. Great medication!"

• Direc...
• Taken for 1 to 6 months
• April 29, 2019

"I have been on 10mg Trintellix for nine weeks. I also take Risperidone and Buspirone. I was on Viibryd before I started this drug. I have had MDD for 24 years, and have been on many anti-depressants. Trintellix is by far the best I've been on. I had a little bit of nausea and vomiting, but really no side effects other than that. The side effects went away after the first three days. Trintellix has regulated my sleep and given me so much more energy and zest for life."

• Jesst...
• April 24, 2017

"It was very difficult titrating up to 20 mg of Trintellix. I started at 5 mg one week; 10 mg the next week, 15 mg the following week until I reached 20 mg. The nausea, vomiting, and dizziness were almost unbearable; I missed 2 days each week for a month while starting it. Thankfully I was on FMLA and was able to muscle through it. I have been through almost every SSRI, SNRI, etc and nothing but electroconvulsive therapy worked for me. After the first week on Trintellix I felt happy for the first time, actually happy, which is why I muscled through the side effects. I have been on it for a year now and it is a miracle pill. Make it through the first month and all side effects go away."

• Digge...
• Taken for 1 to 6 months
• September 12, 2015

"I had given up that there was any drug that could lift me out of the recurring cycles of clinical depression. I had tried dozens of medications over the years, some worked for a time but I came to the point that my depression was at least I thought untreatable. This last bout had me down in bed for nearly 2 months. I was "blessed" to stumble upon Brintellix after my wife had recommended it after seeing it transform one of her patients. The key is it takes a very long time to work and you must be patient. I am now almost 6 weeks in and the depression has completely lifted and feeling better every day. Yes, there are side effects.. headaches, insomnia and confusion but they go away. This drug saved my life! Give it 6-8 week at minimum!"

• Jess
• Taken for 1 to 6 months
• December 13, 2019

"I started taking this medication a little over 3 months ago after trying/failing to successfully taper myself off Lexapro. Lexapro was a great med for treating anxiety for several months but when depression hit, Lexapro did not seem to be helping. My doctor had me switch to Trintellix and I have been amazed at the result. Suicidal ideations are now small enough to ignore and most of the time I can lift myself out of my down moods. I don't think 5mg is quite enough so I will be asking for 10mg soon. If anyone is on the fence about this drug, I say give it a shot. I was really skeptical and the first time my doc suggested it, I gave him a hard no in response. I finally tried it when he suggested it a second time and I do not regret it. Also, my pharmacist found a really great discount coupon...I believe it was through the drug company itself."

• Canary
• March 11, 2019

"I'm 25 years old woman with major depressive disorder + social anxiety for 8 years (with episodes of agoraphoby). Trintellix solved my major depressive disorder in almost 3 weeks!!!. I was very sceptic with the antidepressive meds but this changed my view about it. I'm very happy with this antidepressant. I feel nauseated at times but compared with the symptoms of depression is negligible. Of course this is not a magic bullet, changes in your lifestyle are required: exercise, healthy food, no drinking/smoking... Hope this med help you :)"

• Anonymous
• Taken for 1 to 6 months
• April 14, 2023

"I've been on Trintellix for around 5 months and I've had great results. When I started on the 5mg I definitely felt the nausea, but it went away after being on it for about a week and a half. The nausea only returned when my doctor upped my dosage to 10mg, but it went away after around two weeks once my body got used to it. Since then, I've noticed a huge difference in my overall mood. I feel more stable, generally lighter and happier and the only other side effect I've experienced is very vivid dreams. They aren't unpleasant dreams at all, just incredibly vivid and the kind I always remember when I wake up. But overall, it really is like clouds have parted, I feel stable and hopeful again for the first time since I can remember."

• NKOTB...
• January 25, 2016

"I've been on Brintellix now for 6 weeks, I started on 1/2 of 5mg tablet Bc I hadn't tolerated any other SSRI. Increased to 5mg about 3 weeks ago. I've found a new found hope in life. I had the constipation, but increased my fiber, started on Benefiber daily and increased water consumption and even have had the desire to exercise which also helps. I'm sold on this medication, I haven't felt this good in years!"

• Raven...
• Taken for 1 to 6 months
• October 19, 2019

"I've been on everything for depression you name it: zoloft, Prozac with add-ons like buspar and/or mirtazipine, abilify added to that mix but nothing has worked till I tried Trintellix and I do my extensive research since I study psychopharmacology. Anyway this has been about 80% improvement. The only main side effects is a mild hypomania or what I call a good mood and productive, and some jitteriness like I'll have to pace sometimes. Help my working memory I can remember numbers better but also events I can remember better"

• HumDu...
• Taken for 5 to 10 years
• April 14, 2021

"I have tried every single antidepressant on the market over the past 10 years. They either did not work or caused terrible side effects or I needed a booster med usually an antipsychotic to make it work. I gained 60lbs in 3 years taking other meds. My doctor at first gave me 5mg of Trintellix and then upped me to 10. At 10mg I still needed the booster meds. She upped me to 15mg and took me off the booster meds. I lost around 15lbs and was feeling somewhat better. After upping me 6 weeks ago to 20mg (maximum dose) I am feeling fantastic. Lots of energy, positive thoughts, enjoying life for the first time in 10 years. I have been on Trintellix in some form for almost 5 years and it took that long to get the dosage right. I am grateful for my doctor for sticking with me until we finally found the right combination. I feel like I have a whole new life right now. Trintellix did not cause me weight gain. Abilify, Rexulti, and Bupropion XL did."

• kcw
• Taken for 1 to 6 months
• September 27, 2023

"I have been on it for two months. 20 mg dose daily. The nausea can be bad. But it seems to have cleared out some of the 'gloom' of depression. My libido is dead. I am having muscular pain in my arm but don't know if it is related to the med."

• MRG
• Taken for less than 1 month
• October 13, 2018

"The first day I took my 5mg dose I began to experience minor bouts of dizziness every so often and a decrease in appetite but figured I was just getting used to it and decided I'd wait it out to see if it improved. In just 3 days I became severely dizzy, nauseated and could no longer keep food down. I was disoriented and overwhelmed with an unusual feeling. I was basically unable to function and had to immediately stop the pills. Since then my mood has tanked and I've become irritable and aggressive and have had unusual and impulsive urges. I've never experienced anything quite like it and have seen a lot of other similar experiences. If you start this medicine please inform yourself of the symptoms of serotonin syndrome! While it has done badly for me some people are doing very well on this medication so I can't in good conscience tell people not to try it. I wanted to share my personal experience and hope it informs people!"

• Josie
• Taken for 1 to 6 months
• July 26, 2019

"Had tried several other antidepressants and was close to giving up. Trintellix saved my life. I had increased energy and mood within a couple weeks, started being able to be more active, and was able to think about the future without feeling overwhelmed. It was amazing. I've had depression for years and had forgotten what it felt like to actually be interested in life and not feel like dying every time I woke up in the morning. Side effects have been minimal: lots of nausea that has contributed to some weight loss but not enough to be worrisome, and it lowered my libido and made it slightly harder to orgasm. Compared to other things I tried the side effects are hardly noticeable! BMI: 19.1, Trintellix 15mg daily. I have noticed that if I miss a dose (I take it at night to reduce the nausea) and take it the next morning when I remember, I'm pretty irritable and down already just taking it 12 hours late. Overall, definitely recommend!!"

• Char
• Taken for less than 1 month
• August 28, 2019

"Will probably update later when I’ve been on longer, but so far it’s been very helpful. I’ve been on several antidepressants over the last decade (only one has ever worked and had to be discontinued due to worsening side effects) and had no problem getting approval from insurance. I started on 5 mg for a week and had slight nausea on days 2-5 a couple of hours after taking with food that lasted about 20-30 minutes. I’ve been on 10 mg for a week and no nausea. It’s actually improved my IBS. Appetite has been the same. My depression symptoms mainly manifest as fatigue/exhaustion, brain fog, forgetfulness, lack of motivation. I feel great, I’m motivated, I’ve been working out, getting more done at work and at home, sleeping less (now I’m sleeping more like 8 hours instead of 10-12). My out of pocket is $100 for a 30 day supply of 10 mg, I’m looking in to bringing the cost down, but if I can’t it’ll be well worth it for how good I feel."

• ALM-...
• Taken for 2 to 5 years
• February 20, 2016

"I am on 10mg of Brintellix, and have been for approximately 2 years. This med is a miracle worker for me, I am more stable than I have ever been. However, as a result I experience severe nausea as well as projectile vomiting, if taken after a large meal it is not as bad; within the hour after taking the medication I either feel like I am going to vomit or barely have time to make it to the toilet before vomiting. This is the one negative of this medication, so I have had to choose to deal with this in order to keep the positive outcome in dealing with my MDD; my whole life has changed since starting Brintellix. Vomiting/Nausea is a small price compared to just not living."

• LANIE
• Taken for 1 to 6 months
• September 23, 2020

"I had severe nausea. I would take Trintellix every morning and within one hour after taking this medication I was vomiting severely. It went on for a couple of months and I had to be changed back to Lexapro! I was so disappointed, because it made feel better. Even after I would vomit, I was okay so in order to keep taking the medication I had to be put and take zofran every day. I didn't feel it was worth it so I switched back to Lexapro. Has Anyone else had these side affects. What should I do? Please help me out! Thanks"

• Anonymous
• Taken for 1 to 2 years
• July 2, 2016

"I've been taking this for over a year. Fortunately, I never experienced any of the side effects described by many people here. I always have such high hopes when trying something new for MDD. This medication did not deliver the hoped-for miracle of no more depression, but I must say, my mood has improved to a degree. I am able to get "up" for certain activities now, where this was very difficult while on other medications. This has lightened my mood better than Viibryd or Cymbalta."

• happy...
• October 31, 2014

"I have been depressed for 12 years. Throughout my life I've contemplated suicide, I had paranoid thoughts, and had very little self esteem. I have been on and off multiple antidepressants and couldn't find one that made me feel like myself again. Finally, when I started to experience severe mood swings and found myself becoming angry for no reason to the people I loved, I decided I should try to get help once again. My doctor started me on Brintellix and it has helped me so much. Fortunately, I don't experience any side effects. My mood is elevated, I'm gaining my confidence back, I'm more motivated, and most importantly I feel like myself again. I'm taking 10mg currently and find no need to go to a higher dose. The only downfall is the cost"

• Babyc...
• Taken for less than 1 month
• December 9, 2019

"I’ve been on the 5 mg for about a week now. I switched over from Zoloft because after many years it stopped working. So far I have felt great. I haven’t had any nausea or adverse effects. I up my dose to 10 mg in a day or so, and I’ll update if I notice any changes, good or bad. So far it’s been great though. I would say that the only effect I’ve noticed is my clothes are fitting differently. I haven’t weighed but I think I’ve lost some weight! I’m pretty optimistic."

• Payro...
• Taken for less than 1 month
• October 12, 2018

"I have been on Zoloft for about 5 years with no problems. But recently I started having panic attacks again, was always tired no matter how much I slept, couldn't enjoy life and was having suicidal thoughts again so my GP switched me to Trintellix. I'm about 2 weeks in and so far so good! Almost immediately the suicidal thoughts stopped and I actually have energy again. I am still struggling with not wanting to go out and do things, but am pushing through. I am very happy with the results so far. Side effects are mild nausea for a couple hours after dosing and trouble sleeping. My head is feeling a little "swimmy" at times too, but I think that may be from stopping Zoloft. "

• Tired...
• May 6, 2017

"I have been battling major depression and anxiey for years and was at the point of saying this illness is meant to be my fatality. After several tries on different antidepressants. Trintellix has given me a new outlook on life. If you are at the point of tiresome trial and error do not give up until you try Trintellix. The benefits out way the side effects."