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Orphenadrine User Reviews & Ratings (Page 3)

Orphenadrine has an average rating of 6.7 out of 10 from a total of 83 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 28% reported a negative experience.

Reviews for Orphenadrine

Commonly mentioned side effects
  • Tal...
  • Taken for less than 1 month
  • August 18, 2022

For Muscle Spasm "Man, I wish I had read these reviews before taking it, so I knew what I was in for. This is my third day on it, first night I took it before bed, passed out pretty fast because of how tired I already was. Took one in the morning, then after dinner RIGHT BEFORE I HAD A CLIENT! I do eyelash extensions from home, which involves me using VERY VERY sharp tweezers to put a synthetic eyelash onto EACH natural lash, takes hours, and you need good eyes to separate the lashes. I COULD NOT SEE A THING AND I WAS PANICKING!!! I had to keep closing my eyes then opening them because after I opened them, I could see them for a few seconds, then it went fully blurry again. By some miracle and no lawsuits later, I managed to finish, and it’s been over 24 hours, and vision is still not 100%. My mouth was SOOO dry all day, and my saliva was so thick I thought I was going to choke on it. Flushed cheeks, too."

2 / 10
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4 Report
  • Pai...
  • Taken for 1 to 6 months
  • July 4, 2022

For Muscle Spasm "I was prescribed orphenadrine 100 mg, one tablet twice a day for severe hip pain and muscle spasm in my leg. I can only handle taking one, and I usually take it at night because I can't sleep from the severe pain. It is so amazing how it works for the pain and the spasm, the next day, I feel nothing. I make sure to get lots of sleep because it does make you tired and drink plenty of water, as I get dehydrated from it. It isn't addictive."

10 / 10
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4 Report
  • kea...
  • Taken for 1 to 2 years
  • June 17, 2021

For Muscle Spasm "I've been on a host of antidepressants and opiates. While opiates do relieve my pain slightly more, this is a miracle drug for those who do not want to be on a lifetime of daily medication. The analgesic effect of this drug seems to go hand in hand with nerve pain, although it does not directly help the pain, I find it releases tension in my back, which in turn helps the pain substantially. My only beef with this substance is that it only lasts 4-5 hours, whereas Panadeine or something similar lasts 8-10 hours. Please be aware of anticholinergic effects, it can give weird dreams and hallucinations if not enough choline is present. It's 1/3rd as strong as PCP as an NMDA agonist."

8 / 10
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5 Report
  • Ban...
  • Taken for less than 1 month
  • December 18, 2019

For Muscle Spasm "I was prescribed this orphenadrine on Saturday after going to the ER for what I thought was a torn muscle. Had significant pain in my shoulder area. I took 1 Saturday, 2 Sunday, and 2 on Monday. Within that time frame, my anxiety levels increased, I was hallucinating (feeling 'cancerous lumps' on my body all over, extremely lightheaded at all times, and I got a horrendous migraine). I skipped Tuesday morning's pill and I ended up looking up the side effects Tuesday night, and it all made sense. Here I am Wednesday, still not taking this pill, and I am still having anxiety issues and experiencing the lightheadedness. Also, this didn't even help my pain. Ended up getting a cortisone shot Monday. The only plus side to this was that it made me sleepy. Watch out for the side effects!"

1 / 10
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11 Report
  • Fla...
  • Taken for 1 to 6 months
  • December 23, 2023

Orphenadrine for Muscle Spasm "Aggravated old lower back injury. Spasms with sharp pain. Norflex stopped the spasms which I frequently got while standing or lying down. No side effects other than cotton mouth. I take it day and night, with no daytime fatigue and feel fine at work."

10 / 10
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  • SGa...
  • Taken for 1 to 6 months
  • June 16, 2018

For Muscle Spasm "I was prescribed this medication for pain after I was involved in a car accident and also for back spasms. The drug doesn't really do anything to ease my back and neck pain, but it does act as a pretty good sleep aide. So I guess it's not totally useless. A low rating was given because it does not do what it is prescribed for."

4 / 10
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8 Report
  • Reb...
  • Taken for 1 to 2 years
  • January 28, 2018

For Muscle Spasm "100 mg Norflex is a joke. I'm a 26-year-old achondroplasia little person, and I have severe kyphosis, spinal stenosis, slight scoliosis, and I'm paraplegic. My doctor keeps writing scripts for this medicine, and it does not help at all. My kyphosis (curve by which the spine is bent forward) was bad, and I was bent forward 147 degrees. I keep telling him this isn't helping, and I'm not sleeping at night, but he keeps throwing these at me. He had removed my hardware back in May due to an infection, and I've been in pain ever since, and he swears up and down these will work. Just a joke and a waste... I'm gonna be having surgery again March 19th."

1 / 10
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9 Report
  • Chi...
  • March 5, 2017

For Muscle Spasm "Taking this was one of the most frightening experiences of my life. First, it felt like gravity pulled me to the floor and pinned me down. Then I looked over at my arm, and it appeared to be lying there detached from my body! I wavered between logically asking my husband what this phenomenon was that I was experiencing and being frightened that it might be true. Wondering if this happened to anyone else."

1 / 10
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18 Report
  • Kar...
  • Taken for less than 1 month
  • September 22, 2022

Orphenadrine for Muscle Spasm "After two days of lower back spasms that were increasingly getting worse to where I was having trouble walking, on a pain scale of 1-10 it was 9/10, so I decided to seek medical help. I was prescribed Norflex as a muscle relaxant in 100 mg tablet form. The first dose was in the evening to be taken with Paracetamol and the second dose the next morning. After one day, the spasms are no longer severe and the pain is bearable, 5/10. This medication has been amazing for me, the only side effect is a very dry mouth."

10 / 10
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  • SWh...
  • Taken for 2 to 5 years
  • May 8, 2018

For Migraine "I use one 50 mg tablet of this muscle relaxant along with one or two Naproxen Sodium (Aleve) tablets as a first-line regiment to break an initial starting migraine. For some early/mild migraines, this can give relief. When not caught early (within 1 hr) or it is a moderate migraine, the second-line regiment includes a 2nd Orphenadrine dose and a 50 mg Tramadol (Ultram), which usually provides relief in addition to lying down, relaxing in a dark, quiet, cool room. Strong migraines use a third-line regiment of a 2nd Tramadol, coffee (caffeine), warm shower/bath, foot/hand massage, soothing music, as well as a dark, quiet, cool room."

5 / 10
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6 Report
  • Car...
  • Taken for 1 to 6 months
  • August 21, 2023

For Muscle Spasm "Good medicine for muscle pain. Side effects feel like taking NyQuil, but wear off in a few days. I have heart failure, and for some reason, Orphenadrine also eliminated my constant heart palpitations/PVCs. A nice surprise!"

8 / 10
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1 Report
  • Ric...
  • Taken for 1 to 6 months
  • March 29, 2018

For Muscle Spasm "Very expensive and does absolutely nothing to stop spasms or muscle pain, not even a very mild headache. Get more relief out of an 81 mg baby aspirin. Everyone I asked about this drug says it's worthless."

1 / 10
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6 Report
  • Per...
  • Taken for 10 years or more
  • June 13, 2019

Orphenadrine for Muscle Spasm "Due to cervical and lumbar spinal injury, Norflex worked the best (with a painkiller when needed) compared to other drugs and there are tremendous side effects."

9 / 10
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38 Report
  • Slu...
  • Taken for less than 1 month
  • August 9, 2015

Orphenadrine for Muscle Spasm "Norflex has affected my speech. Sometimes I can't get the words out of my mouth."

1 / 10
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48 Report
  • Gwe...
  • Taken for 10 years or more
  • October 27, 2013

For Muscle Spasm "Thoracic and lumbar issues cause constant muscle spasms. Orphenadrine E.R. helps tame them. It is also the least of the evils when it comes to causing drowsiness."

10 / 10
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39 Report
  • vau...
  • April 19, 2010

Orphenadrine for Migraine "Made me blurry, drowsy, and cognitive dulling. Short trial only (two weeks), then stopped due to side effects."

3 / 10
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48 Report
  • 737...
  • February 9, 2021

Orphenadrine for Muscle Spasm "Am taking Norflex for neck pain. It worked at first, and now the pain is back. The side effects are strong, lightheaded, dizzy, and dry mouth."

6 / 10
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15 Report
  • Eca...
  • January 24, 2018

Orphenadrine for Migraine "Only drug that has broken a bad 1-week cycle of migraines. One IM injection and my head starts to feel better within the hour."

10 / 10
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22 Report
  • vic...
  • March 29, 2008

Orphenadrine for Muscle Spasm "I was doing well on this for about the first 2 months, now it seems I need something a bit stronger. Looking for the next upgrade."

6 / 10
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50 Report
  • Jud...
  • February 16, 2009

Orphenadrine for Muscle Spasm "I was given the medication by my family doctor for a muscle I pulled in my back. Even after 3 days, I am still in pain. It has done nothing for me."

1 / 10
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45 Report
  • Dew...
  • Taken for less than 1 month
  • March 6, 2013

For Migraine "I ended up in ICU with heart palpitations (over 200 bpm). I only took one tablet of Norflex, and this happened almost 6 hours after taking it. Turns out I'm allergic to orphenadrine."

1 / 10
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29 Report
  • bre...
  • July 15, 2011

For Muscle Spasm "Just started taking them for my back pain, and I feel better already."

10 / 10
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25 Report
  • nik...
  • Taken for less than 1 month
  • May 17, 2019

Orphenadrine for Migraine "This medication, Antiflex, I was recommended to by my doctor. It helps with migraines and helps with cramps. It's really useful."

10 / 10
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14 Report
  • InS...
  • Taken for 6 months to 1 year
  • January 2, 2017

For Muscle Spasm "Mild effect on acute body pain."

3 / 10
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13 Report
  • Dan...
  • February 28, 2016

For Muscle Spasm "Best tablet I've ever been given for severe muscle spasms. Did make me very groggy, fell asleep sitting up at night numerous times as couldn't stay up past 8 pm."

10 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.