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Orphenadrine and Tremors: What Users Say

Tremors: mentioned by 5 users (6.0%)

Based on user experiences from 83 Orphenadrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.0%
dry mouth 9.6%
dizziness 8.4%
drowsiness 6.0%
lightheadedness 6.0%
tremors 6.0%
nausea 4.8%
headaches 3.6%
irritability 3.6%

Reviews for Orphenadrine

Commonly mentioned side effects
  • Gym...
  • Taken for less than 1 month
  • November 11, 2019

Orphenadrine for Muscle Spasm "Worst medicine I have ever taken. I took two 100 mg tablets, and after 2 hours, I couldn't read, focus, or swallow. I had tremors that lasted two days and severe anxiety. I felt like I was completely paralyzed, unable to lift my arms. No one warned me about the side effects, and I had no idea it could be this bad."

1 / 10
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98 Report
  • Hon...
  • Taken for less than 1 month
  • October 19, 2022

Orphenadrine for Muscle Spasm "I have had tight neck and shoulder muscles with cervicogenic headaches for 25 years, along with arthritis in my neck, and have tried everything to ease the pain. I saw a specialist who gave me Norflex. I started on 1/2 tablet (50 mg) once a day for 7 days, and my neck pain reduced dramatically, and I haven’t had any headaches. I then increased the dose to 1 tablet (100 mg) as recommended by my doctor. After the 3rd day, I had a massive panic attack that lasted about half a day. I couldn’t stop shaking and had trouble catching my breath. I felt anxious and agitated. It was very scary, and I ended up in the emergency room for a few hours. I have gone back to the 1/2 tablet, and hopefully my body will adjust to the medication over time, as it’s the only thing that has helped my condition."

8 / 10
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8 Report
  • Anonymous
  • Taken for less than 1 month
  • April 10, 2022

Orphenadrine for Muscle Spasm "I can't say it has really made any difference. However, once I started taking 1x 100 mg at night and 1x 50 mg in the morning, my eyesight has been affected, my hands are shaking, and my anxiety is next level. I also can't focus on any daily important tasks. I have herniated disks in my back, hip, and knee pain issues."

2 / 10
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9 Report

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  • Joe...
  • April 14, 2018

For Migraine "I was prescribed this for my migraines and slight muscle spasms. The first day after taking it, I was having frequent urination, dry mouth, dizziness, nausea, hot flashes, and confusion. I continued taking it for 7 days, but the side effects became worse. Nausea turned to vomiting. Eyes became so blurry I couldn't read anymore. My arms and face started getting tremors, and I was having pressure in my face. I started getting extreme episodes of anxiety. I discontinued the medication, and everything has slowly gotten better. It's been about 11 days, and I still am dealing with the nausea, but everything else has almost gone away. Just nausea and tremors still remain."

1 / 10
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16 Report
  • Kan...
  • April 10, 2021

For Muscle Spasm "I used Norflex, and it was the worst decision ever. Two days in, I was lightheaded, my eye was painful, dry mouth, tremors from hand to my feet, and whole body weakness."

1 / 10
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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.