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User Reviews for Orphenadrine

Condition Avg. Rating Reviews Compare
Muscle Spasm  
6.9
52 reviews 50 medications
Migraine  Off-label
6.9
10 reviews 87 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Orphenadrine

K April 10, 2021

For Muscle Spasm: “I used norflex and it was the worse decision ever two days in I was light headed, my eye was painful, dry mouth, tremors from hand to my feet and whole body weakness.”

1 / 10
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J · Taken for 1 to 2 years March 24, 2021

For Muscle Spasm: “I have been thru every muscle relaxers and for me Orphenadrine has been the one that helps the best. It's an older medication and sometimes hard to find, and some insurance don't like covering it. But it's really worth the 30 bucks I pay per month.”

10 / 10
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737 February 9, 2021

Norflex (orphenadrine) for Muscle Spasm: “Am taking Norflex for neck pain, it worked at first and now the pain is back. The side effects are strong, lightheaded, dizzy and dry mouth.”

6 / 10
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Nicholasp · Taken for less than 1 month June 25, 2016

Norflex (orphenadrine) for Muscle Spasm: “After experiencing a nasty bulge disc , L5/6 and diagnosed with retro lethesis I spent 3 years from chiro to physio , but couldn't kick the intense pain in my back which would go all over my back. At times I'd be in bed for days. I saw a pain specialist and was given norflex. I took 100mg once a day and after 2 days I was pain free. I now only take it when it flares which isn't often. It changed my life for the better.”

9 / 10
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Gymbunny · Taken for less than 1 month November 11, 2019

Norflex (orphenadrine) for Muscle Spasm: “Worst medicine I have ever taken. I took two 100mg tablets and after 2 hours I couldn't read, focus or swallow. I had tremors that lasted two days and severe anxiety. I felt like I was completely paralysed, unable to lift my arms. No one warned me about the side effects and I had no idea it could be this bad.”

1 / 10
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Todd · Taken for less than 1 month May 21, 2019

Norflex (orphenadrine) for Muscle Spasm: “I had chronic lower back pain for several months which was muscle related and spread to my abdomen over time. I was prescribed Norlfex, first day it didn't do much, day 2 I took it again and then at the end of the day had a dissociative episode and the start of anxiety. Almost like a panic attack was about to kick off. I had battled anxiety for several years and weaned myself off Paroxetine nearly a decade and a half prior so it felt like it was all coming back. Googled after and found a side effect is...anxiety. Be careful if you are prone to this.”

4 / 10
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BellaGirlSmiles June 9, 2015

Norflex (orphenadrine) for Muscle Spasm: “I have 2 discs that press on my spine in my neck, as well as fibromyalgia, rheumatoid arthritis & an auto-immune disease. I recently came off of Methadone & Percocet, unintentionally, when I had just enough to get to my appointment with the pain specialist I was scheduled to see for the 1st time, but he got sick & they had to reschedule me. In addition to withdrawal, my pain level kept rising, to the point that every bone & muscle in my body hurt worse than I have ever been in!!! It's the only time I've ever used "9.9" to describe my pain! I have had to go to the ER several times in the last month. I was given Norflex 2 of those times, when I had a pinched nerve. Norflex helped SO MUCH MORE than ANY of the muscle relaxers I had at home!”

10 / 10
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Steff January 9, 2021

Norflex (orphenadrine) for Muscle Spasm: “I had a reversal ostomy yesterday. I'm currently in the hospital. I researched this medication. After it was given to me and it worked. Worked miracle for me. I can't take anything by mouth. This worked excellent”

10 / 10
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BSC1819 June 28, 2011

Norflex (orphenadrine) for Muscle Spasm: “Had a herniated disc in between my L-5,S-1 vertebrae and had been prescribed Percocet for 7 months. Had 3 epidural steroid injections that worked for a while but then faded away. Finally had surgery and as a bodybuilder had a lot of muscle in my lower back to cut through to shave the disk off of the nerve. Was prescribed the Percocet still and Soma for muscle spasms and pain. All Soma did was make me pass out with little effect. Was currently changed to Norflex for the spasms and I only take 1 pill a day and it has done wonders without any side affects. Highly recommended for anyone with spasms or migraines.”

9 / 10
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granny granny · Taken for less than 1 month February 15, 2013

Norflex (orphenadrine) for Muscle Spasm: “I so grateful to find something to stop the spasms in my back! The spasms were coming about every 3 minutes much like labor pains! Pain killers were not working. Before taking Norflex, it took about a month to get through the spasms. I have been taking Norflex for the past three days and the relief is wonderful.”

10 / 10
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AngiePants · Taken for less than 1 month May 12, 2020

Norflex (orphenadrine) for Muscle Spasm: “Took it to ease the pain in my jaw from clenching my jaw and grinding my teeth in my sleep only took 1 tablet at night made me sleepy but definitely helped with the jaw pain until my mouth guard was ready”

9 / 10
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Kandi lady · Taken for less than 1 month February 19, 2015

Norflex (orphenadrine) for Muscle Spasm: “I was given this medicine for muscle spasms in the emergency room after 3 visits and 2 different hospitals. First I received an injection of Norflex and than a prescription for 2 a day for eight days. These pills worked wonders for the muscle spasms I had been having for about 3 months. I have been pain free for 4 months now.”

9 / 10
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Moray February 19, 2017

Norflex (orphenadrine) for Muscle Spasm: “I've been suffering from various back and nerve issues for almost a year now; 2 bulging discs and sciatica. Over the holidays I was unable to get in to see my primary care and ran out of my medications, resulting in a trip to the ER. The ER doc gave me an injection of Norflex and an rx until I was able to get in and see my doc. It has worked amazingly well. I've had minimal side effects taking it twice daily and within a half hour of taking it, my back spasms completely stop. It's been quite a relief.”

9 / 10
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Gigi · Taken for less than 1 month September 14, 2018

Norflex (orphenadrine) for Muscle Spasm: “I have spina bifida with a lot of pain. I’m a former addict so I can’t take narcotics when the chronic pain is out of control. When I’m in bad shape my doc gives to shots (IM) of 60 mg of Norflex and 60 mg of toradol...and the two together work so well on my pain-and it lasts all day and I can FUNCTION. The sad part is I can only get these shots once every 6 weeks or so because insurance won’t pay for it and it’s hard on your liver I guess. But to have a combination of drugs that work so well on pain and is non-addictive...they should be used more for those whom are suffering.”

9 / 10
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KevinfromFlorida September 21, 2008

Norflex (orphenadrine) for Muscle Spasm: “I find Norflex to be an amazing treatment for neck muscle spasms. I lead a pretty stressful life and every now (once every 3 months or so) and then suffer from muscle spasms in my neck and upper shoulder areas. This can be extremely painful. Sometimes by just taking 2 tables before I go to bed, will cure the problem. I have never needed to take more than 3 doses to relieve the spasm. There have been occasions that I did not have any Norflex and it will take quite a few days for the spasm to pass, even with regular massaging.”

10 / 10
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love life January 27, 2013

Norflex (orphenadrine) for Muscle Spasm: “I found Norflex the only medicine that help to reduce my whiplash pain with minimal side effects. I only take one tablet in the morning on rising, it changed my life by reducing the severe pain of whiplash.”

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Cuy · Taken for 6 months to 1 year July 13, 2015

Norflex (orphenadrine) for Muscle Spasm: “Very usefull for stress and muscle pain. But in the beginning a lot of side effects, due to the fact that I took 100 mg a day. (I only weight 45 kg). Now I"m taking 1/2 every day, sometimes every two days. I feel very good, and my husband is very happy, it saved my relation.”

10 / 10
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Shajinka · Taken for less than 1 month February 11, 2015

Norflex (orphenadrine) for Muscle Spasm: “I was perscribed 2 100 mg tablets twice a day for muscle spasms. This is the worst experience I have ever had. Only took 2 1 in morning and 1 in evening. I was up for 3 days straight jittery, agitated, mildly confused and spaced out. I had no pain but could not function a normal life on Norflex. I am 120 pounds.”

4 / 10
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Nurse56 · Taken for 2 to 5 years November 8, 2012

Norflex (orphenadrine) for Muscle Spasm: “I was given this while living in the Philippines as a combo med with Acetaminophen. It worked better than any pain medicine I had ever used without the side effects of stomach upset (Ibuprofen) or fatigue, sleepiness (codeine). ”

9 / 10
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BabyGirl · Taken for 1 to 6 months November 8, 2019

For Muscle Spasm: “I'm normally prescribed Cyclobenzaprine (Flexeril), but asked my doctor to give me this Orphenadrine (Norflex) after they gave me a muscle injection of it in the ER , for a bad tension headache I had. I have upper back and neck spasms, had a second terrible tension headache for 2 weeks until I finally came to my senses and took this pill for a few days (I hate taking medicine), it really really helped relieve the headache. Also helps me sleep good, normally I wake up every few hours but when I take this I knock out for 6 hours straight.”

10 / 10
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Chaddo · Taken for less than 1 month February 4, 2018

Norflex (orphenadrine) for Muscle Spasm: “took this medication for 3 days within 24 hours I could not read anything couldn't even read my watch. Pupils completely dilated like when I took powerful drugs in my 20s. This is some scary shit, the walls and floor in my toilet were also dripping like being on LSD, loss of balance as well. Now day 3 stopped, taking by 9pm 14hours later can sort of read again on my laptop and write this info. Does not agree with my”

5 / 10
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Pinky · Taken for less than 1 month January 23, 2020

For Muscle Spasm: “The orphenadrine best medication I've taken to relieve my modest muscle spasms on my both thighs, sciatica, bulging back & neck discs, fibromyalgia. I was so happy and pain free until the morning of the 3rd day. I took a 100mg at 8am, by 11am I felt weird, I tried lifting my head, felt like my body was detached, everything I did was in slow motion, forgetfulness, little stuttering, dry mouth, felt like this for two days, I decided to stay home not drive, drank lots of water to flush out meds..Started to feel better after the 3rd day , back to normal on 4th day..If it wasn't for the side effects, I would have finally found the perfect med. I give it a 10.”

10 / 10
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Lulu · Taken for 5 to 10 years August 15, 2018

For Muscle Spasm: “I have had severe muscle spasms in my mid and lower back for years. Was first prescribed methacarbomol but it wasn’t strong enough and gave me weird dreams. My doctor then prescribed orphenadrine and it does exactly what I need it to. Every time. It has never made me drowsy. I only take it when I need it such as when I’m driving all day or having to stand a lot. It has been wonderful!!”

10 / 10
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Oz · Taken for 6 months to 1 year April 11, 2018

Norflex (orphenadrine) for Muscle Spasm: “I have had lower back pain from degenerated disc since my 30's caused by a fall from a horse, then the same problem in my neck from a car accident. A few years ago I started getting what I put down to sciatica, then my right leg started collapsing on me and I have had several falls. I have strange effects to most medications they seem to affect me different to the norm, Norflex works perfectly on the pain side of things and generally reduces the falling. ( For migraines btw Relpax is amazing.) Norflex is now unavailable and I am desperate to know what to do I am back on Palexia but it has heaps of side effects and doesn't do the job.”

10 / 10
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Ryan · Taken for less than 1 month January 5, 2020

For Muscle Spasm: “Did not experience any bad side effects whatsoever. It didn't 'cure' my lower back pain but made it almost un-noticeable. I took on pill/tablet shortly before I went to sleep at night. My back problem cleared up on about 3 days which is unheard of for me.”

8 / 10
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Freelife · Taken for 5 to 10 years October 18, 2020

For Muscle Spasm: “I was prescribed orphenadrine 6 years ago for neck spasms. Everything described here is accurate and the benefits were great. A week ago I decided to stop taking this because I no longer want to be dependent on a muscle relaxer.”

9 / 10
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Jess · Taken for 1 to 6 months January 21, 2021

For Muscle Spasm: “I am so thankful these orphenadrine exist. For yeeears I have had neck and shoulder pain to the point of bad headaches! NOOOOOTHING made it better doc put me on 5mg lexapro after trying everything else, when taking lexapro on the lowest dose it is actually more of a pain reliever, took this but still got it in and off. One day I had very bad lower back pain and was prescribed Norgesic. OMG HEAVEN!!!!! Seriously! Changed my life. I am reading a lot about anxiety on here and I have had anxiety forever but I have to say this does not cause any anxiety for me... seems like it’s made it better so it’s odd about the anxiety... I have absolutely no side effects! Anyway it is a life saver for me xx”

10 / 10
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Cuey · Taken for 5 to 10 years September 6, 2018

For Muscle Spasm: “Not all generic versions of Orphenadrine agree with me. I have given instructions to my pharmacist to only provide one kind of generic. So maybe that is why others have not been helped by this drug. This muscle relaxer works very well for me when I am in a bad flare up of pain. I have Rheumatoid Arthritis, osteoarthritis, and degenerative neck and spine, also sciatic pain. Pain all over. I only use it when absolutely necessary along with Tramadol or Diclofenac - the only meds I use for pain. No dizziness nor nausea or creepy side effects. My medicare advantage plan will not pay for it. I pay out of pocket.. The pain specialist who prescribed it to me is retired now so I cannot get a script for it. I am seeing another pain doctor next week and hope they will RX it for me.”

10 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.