Skip to main content

Orphenadrine and Nausea: What Users Say

Nausea: mentioned by 4 users (4.8%)

Based on user experiences from 83 Orphenadrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.0%
dry mouth 9.6%
dizziness 8.4%
drowsiness 6.0%
lightheadedness 6.0%
tremors 6.0%
nausea 4.8%
headaches 3.6%
irritability 3.6%

Reviews for Orphenadrine

Commonly mentioned side effects
  • Anonymous
  • February 26, 2023

Orphenadrine for Muscle Spasm "Taking this medication was totally not for me. I have suffered anxiety all my life, but it’s controlled on medication, but when I was prescribed this, my anxiety was next level. I’ve never felt so horrible in all my life. I was irritable, nauseous, fidgety, felt like constant panic, tense, and didn’t help my condition at all. Obviously, everyone is different, but it’s not for me and I will never take this again."

1 / 10
Was this helpful?YesNo
15 Report
  • Cue...
  • Taken for 5 to 10 years
  • September 6, 2018

For Muscle Spasm "Not all generic versions of orphenadrine agree with me. I have given instructions to my pharmacist to only provide one kind of generic. So maybe that is why others have not been helped by this drug. This muscle relaxer works very well for me when I am in a bad flare-up of pain. I have rheumatoid arthritis, osteoarthritis, and degenerative neck and spine, also sciatic pain. Pain all over. I only use it when absolutely necessary along with tramadol or diclofenac - the only meds I use for pain. No dizziness nor nausea or creepy side effects. My Medicare Advantage plan will not pay for it. I pay out of pocket. The pain specialist who prescribed it to me is retired now, so I cannot get a script for it. I am seeing another pain doctor next week and hope they will RX it for me."

10 / 10
Was this helpful?YesNo
23 Report
  • she...
  • December 3, 2015

For Muscle Spasm "6 days of 2 pills a day, and it ended me in the hospital with extreme vomiting, nausea, swollen feet, dizziness. Eventually, a stomach ulcer was found. 5 days in the hospital, lost 5 kgs over a week, now 51 kgs. I would never recommend it to anyone."

2 / 10
Was this helpful?YesNo
26 Report

See also:

  • Joe...
  • April 14, 2018

For Migraine "I was prescribed this for my migraines and slight muscle spasms. The first day after taking it, I was having frequent urination, dry mouth, dizziness, nausea, hot flashes, and confusion. I continued taking it for 7 days, but the side effects became worse. Nausea turned to vomiting. Eyes became so blurry I couldn't read anymore. My arms and face started getting tremors, and I was having pressure in my face. I started getting extreme episodes of anxiety. I discontinued the medication, and everything has slowly gotten better. It's been about 11 days, and I still am dealing with the nausea, but everything else has almost gone away. Just nausea and tremors still remain."

1 / 10
Was this helpful?YesNo
16 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.