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Orphenadrine and Dry Mouth: What Users Say

Dry mouth: mentioned by 8 users (9.6%)

Based on user experiences from 83 Orphenadrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.0%
dry mouth 9.6%
dizziness 8.4%
drowsiness 6.0%
lightheadedness 6.0%
tremors 6.0%
nausea 4.8%
headaches 3.6%
irritability 3.6%

Reviews for Orphenadrine

Commonly mentioned side effects
  • Rox...
  • Taken for less than 1 month
  • August 16, 2021

Orphenadrine for Muscle Spasm "A pharmacist gave me Brufen tablets to take during the day and Norflex at night. I took one tablet of Norflex before bed, only to wake up in the middle of the night in pain again, and it felt worse. I decided to take another tablet so that I could sleep again, but two hours later, I woke up with the urge to go to the bathroom. I laid there paralyzed, and it felt like my brain was swimming in my skull. I couldn't even speak to warn my partner about how I was feeling. Eventually, I rolled onto my side, grabbing the wall next to my bed to help me get up. It's been 11 hours since I took the last pill, and I am still feeling the effects of it. The effects I experienced so far with it are dry mouth, unbalanced, confused, difficulty with speech, very sleepy, and being paralyzed."

1 / 10
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19 Report
  • Pin...
  • Taken for less than 1 month
  • January 23, 2020

For Muscle Spasm "The orphenadrine is the best medication I've taken to relieve my modest muscle spasms in both thighs, sciatica, bulging back and neck discs, fibromyalgia. I was so happy and pain-free until the morning of the 3rd day. I took 100 mg at 8 am, by 11 am, I felt weird. I tried lifting my head, it felt like my body was detached. Everything I did was in slow motion: forgetfulness, little stuttering, dry mouth. I felt like this for two days. I decided to stay home, not drive, and drank lots of water to flush out the meds. I started to feel better after the 3rd day and was back to normal on the 4th day. If it wasn't for the side effects, I would have finally found the perfect med. I give it a 10."

10 / 10
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18 Report
  • Joe...
  • April 14, 2018

For Migraine "I was prescribed this for my migraines and slight muscle spasms. The first day after taking it, I was having frequent urination, dry mouth, dizziness, nausea, hot flashes, and confusion. I continued taking it for 7 days, but the side effects became worse. Nausea turned to vomiting. Eyes became so blurry I couldn't read anymore. My arms and face started getting tremors, and I was having pressure in my face. I started getting extreme episodes of anxiety. I discontinued the medication, and everything has slowly gotten better. It's been about 11 days, and I still am dealing with the nausea, but everything else has almost gone away. Just nausea and tremors still remain."

1 / 10
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16 Report
  • Tal...
  • Taken for less than 1 month
  • August 18, 2022

For Muscle Spasm "Man, I wish I had read these reviews before taking it, so I knew what I was in for. This is my third day on it, first night I took it before bed, passed out pretty fast because of how tired I already was. Took one in the morning, then after dinner RIGHT BEFORE I HAD A CLIENT! I do eyelash extensions from home, which involves me using VERY VERY sharp tweezers to put a synthetic eyelash onto EACH natural lash, takes hours, and you need good eyes to separate the lashes. I COULD NOT SEE A THING AND I WAS PANICKING!!! I had to keep closing my eyes then opening them because after I opened them, I could see them for a few seconds, then it went fully blurry again. By some miracle and no lawsuits later, I managed to finish, and it’s been over 24 hours, and vision is still not 100%. My mouth was SOOO dry all day, and my saliva was so thick I thought I was going to choke on it. Flushed cheeks, too."

2 / 10
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4 Report
  • Kar...
  • Taken for less than 1 month
  • September 22, 2022

Orphenadrine for Muscle Spasm "After two days of lower back spasms that were increasingly getting worse to where I was having trouble walking, on a pain scale of 1-10 it was 9/10, so I decided to seek medical help. I was prescribed Norflex as a muscle relaxant in 100 mg tablet form. The first dose was in the evening to be taken with Paracetamol and the second dose the next morning. After one day, the spasms are no longer severe and the pain is bearable, 5/10. This medication has been amazing for me, the only side effect is a very dry mouth."

10 / 10
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2 Report

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  • 737...
  • February 9, 2021

Orphenadrine for Muscle Spasm "Am taking Norflex for neck pain. It worked at first, and now the pain is back. The side effects are strong, lightheaded, dizzy, and dry mouth."

6 / 10
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15 Report
  • Kan...
  • April 10, 2021

For Muscle Spasm "I used Norflex, and it was the worst decision ever. Two days in, I was lightheaded, my eye was painful, dry mouth, tremors from hand to my feet, and whole body weakness."

1 / 10
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6 Report
  • Nor...
  • April 5, 2022

Orphenadrine for Muscle Spasm "The major experience is the side effect of a very dry mouth."

5 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.