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Orphenadrine User Reviews & Ratings (Page 2)

Orphenadrine has an average rating of 6.7 out of 10 from a total of 81 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Orphenadrine

  • Pinky
  • Taken for less than 1 month
  • January 23, 2020

For Muscle Spasm "The orphenadrine best medication I've taken to relieve my modest muscle spasms on my both thighs, sciatica, bulging back & neck discs, fibromyalgia. I was so happy and pain free until the morning of the 3rd day. I took a 100mg at 8am, by 11am I felt weird, I tried lifting my head, felt like my body was detached, everything I did was in slow motion, forgetfulness, little stuttering, dry mouth, felt like this for two days, I decided to stay home not drive, drank lots of water to flush out meds..Started to feel better after the 3rd day , back to normal on 4th day..If it wasn't for the side effects, I would have finally found the perfect med. I give it a 10."

10 / 10
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18 Report
  • Cuey
  • Taken for 5 to 10 years
  • September 6, 2018

For Muscle Spasm "Not all generic versions of Orphenadrine agree with me. I have given instructions to my pharmacist to only provide one kind of generic. So maybe that is why others have not been helped by this drug. This muscle relaxer works very well for me when I am in a bad flare up of pain. I have Rheumatoid Arthritis, osteoarthritis, and degenerative neck and spine, also sciatic pain. Pain all over. I only use it when absolutely necessary along with Tramadol or Diclofenac - the only meds I use for pain. No dizziness nor nausea or creepy side effects. My medicare advantage plan will not pay for it. I pay out of pocket.. The pain specialist who prescribed it to me is retired now so I cannot get a script for it. I am seeing another pain doctor next week and hope they will RX it for me."

10 / 10
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21 Report
  • Deon...
  • Taken for less than 1 month
  • August 12, 2021

Norflex (orphenadrine) for Muscle Spasm "I have been suffering of serious spasm in my trapezius muscles for at least 3 months, tried many products as well as home remedies. Nothing realy solved my problem, just temporary relieve from pain. Got Norflex from my local Pharmacy, took one tablet last night before bedtiime, and already I can feel a huge difference. No side effects. It looks like I have found a solution to my constant neck and upper back pains."

8 / 10
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12 Report
  • Ryan
  • Taken for less than 1 month
  • January 5, 2020

For Muscle Spasm "Did not experience any bad side effects whatsoever. It didn't 'cure' my lower back pain but made it almost un-noticeable. I took on pill/tablet shortly before I went to sleep at night. My back problem cleared up on about 3 days which is unheard of for me."

8 / 10
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16 Report
  • sheepo
  • December 3, 2015

For Muscle Spasm "6 days of 2 pills a day and it ended me in hospital with extreme vomiting, nausea, swollen feet, dizziness , eventually a stomach ulcer was found, 5 Days in Hospital, lost 5 kgs over a week, now 51kgs. I would never recommend it to anyone."

2 / 10
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26 Report

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  • Snap_...
  • April 1, 2012

For Muscle Spasm "I have severe osteoarthritis of hip-knee-spine. This medicine has minimized the spasm I get in my right hip and the spasm and nerve pain from sciatic nerve compression in the right leg. Helps with 'restless leg' also."

7 / 10
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34 Report
  • Honda...
  • Taken for less than 1 month
  • October 19, 2022

Norflex (orphenadrine) for Muscle Spasm "I have had tight neck and shoulder muscles with cervicogenic headaches for 25 years along with arthritis in my neck and have tried everything to ease the pain. I saw a specialist who gave me Norflex, I started on 1/2 tablet (50mg) once a day and for 7 days and my neck pain reduced dramatically and haven’t had any headaches. I then increased the dose to 1 tablet (100mg) as recommended by my Doctor, after the 3rd day I had a massive panic attack that lasted about half a day, I couldn’t stop shaking and had trouble catching my breath, I felt anxious and agitated, it was very scary and I ended up in they emergency room for a few hours. I have gone back to the 1/2 tablet and hopefully my body will adjust to the medication over time as it’s the only thing that has helped my condition."

8 / 10
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7 Report
  • Aching...
  • December 8, 2012

For Muscle Spasm "After several years of Flexerill, Baclofen, Soma, etc. my Doctor decided to try Orphenadrine. I fell as a teen and cracked several vertebra, DDD, osteoarthritis, sciatica along with neuromuscular demyelination and four (4) herniated lumbar disks. Two failed surgeries caused part of the problems (scar tissue removal around the nerves). The muscle spasms and sciatica are very intense, Orphenadrine is leaps and bounds over everything other than Soma, like many others Soma just puts me out. Two 100mg caps a day along with three baclofen (and my other meds) has made a tremendous difference."

9 / 10
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31 Report
  • Roror...
  • August 8, 2015

For Muscle Spasm "Took 50 mg - cut a 100 mg ER pill in half, for muscle relief a few weeks after a minor car accident. Am 125 pounds. Over 20 hours later, still affected by droopiness, tiredness, and mild headache. Took a long walk and could barely get through it, ended up falling asleep in the afternoon. On the plus side, muscle and joint pain was negligible today. However, also couldn't think or do much either. Would not take again."

5 / 10
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24 Report
  • oneida...
  • December 21, 2009

For Muscle Spasm "I started having severe lower back pain in 1995 and was prescribed Flexeril at the time. I ended up staying on it until 2009. My new doctor decided to take me off it for 3-months and I ended up in the ER with my back in severe pain, every 3 weeks like clockwork. They decided to try the ophenadrine at 100mg. I take it once a day in the morning and I haven't felt so good in all the years. I was on the Flexeril 40mg. I don't know how long it will keep working but I've been taking one a day for a whole month now and I'm about to run out.. with no refills. I'm very-nervous about the pain coming back but for now I give this medicine a thumbs up."

9 / 10
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33 Report
  • karen...
  • July 28, 2014

For Migraine "I suffered for years, this is the only medicine that got rid of my migraines. Everything else just calmed the migraines down but they did not go away. I also found it worked for seasickness, I would get violently sick even on mild water. Now I can enjoy the ocean. I now will be the only one not sick on rough days. I take it with an aspirin and caffeine pill. If you find it doesn't work you might have to up the dose."

10 / 10
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23 Report
  • Joe
  • April 14, 2018

For Migraine "I was prescribed this for my migraines and slight muscle spasms. The first day after taking it, I was having frequent urination, dry mouth, dizziness, nausea, hot flashes, and confusion. I continued taking it for 7 days, but the side effects became worse. Nausea turned to vomiting. Eyes became so blurry I couldn't read anymore. My arms and face started getting tremors and I was having pressure in my face. I started getting extreme episodes of anxiety. I discontinued the medication and everything has slowly gotten better. It's been about 11 days and I still am dealing with the nausea, but everything else has almost gone away. Just nausea and tremors still remain."

1 / 10
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16 Report
  • Chili...
  • March 5, 2017

For Muscle Spasm "Taking this was one of the most frightening experiences of my life. First, if it like gravity pulled me me to the floor and pinned me down. Then I looked over at my arm, and it appeared to be lying there detached from my body! I wavered between logically asking my husband what this phenomenon was I was experiencing, and being frightened that it might be true. Wondering if this happened to anyone else."

1 / 10
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17 Report
  • Lexi
  • Taken for less than 1 month
  • March 12, 2019

For Muscle Spasm "I had pneumonia and bronchitis which caused me to pull a muscle in my chest. This caused panic attacks so the hospital prescribed me Norflex 100mg. I've taken this now 3x all of which has caused light headedness, headaches, upset stomach, and tightening of my chest. I have had panic attacks when this was given to help ease them. Scary for me"

2 / 10
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13 Report
  • Bano
  • Taken for less than 1 month
  • December 18, 2019

For Muscle Spasm "I was prescribed this orphenadrine on Saturday after going to the ER for what I thought was a torn muscle. Had significant pain in my shoulder area. I took 1 Saturday, 2 Sunday, and 2 on Monday. Within that time frame my anxiety levels increased, I was hallucinating (feeling "cancerous lumps" on my body all over, extremely lightheaded at all times, and I got a horrendous migraine). I skipped Tuesday mornings pill and I need up looking up the side effects Tuesday night and it all made sense. Here I am Wednesday, still not taking this pill and I am still having anxiety issues and experiencing the light headedness. Also, this didn't even help my pain. Ended up getting a cortisone shot Monday. The only plus side to this was that it made me sleepy. Watch out for the side effects!"

1 / 10
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11 Report
  • Lala
  • Taken for less than 1 month
  • March 22, 2018

For Muscle Spasm "I was in a car accident that jerked my back and neck all out of whack and was having TERRIBLE muscle spasms worse then when I would pull my back out on my own. I went to the walk in medical centre and was prescribed these instead of flexoral for once. Right after I took the first pill it was amazing relief about an hour later I couldn’t believe it!"

10 / 10
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14 Report
  • Anonymous
  • Taken for less than 1 month
  • September 17, 2022

For Migraine "So I used to take this like once or twice a week as needed and it would help. But one day I had really bad head pain and was freaking out it wouldn’t go away. I took one pill Friday night, Saturday I took one in morning and one at night then Sunday morning. By Sunday afternoon all of a sudden I couldn’t see properly it was freaking me out. Then by Sunday night I had intense anxiety like I suffer from anxiety but never ever like I did with this med and it lasted 3 days with INTENSE like panic attack for 27/4 I can’t even explain. After a few days the intense anxiety lifted but turned into just regular anxiety and all the while I got this weird lightheaded dizzy feeling in my head. I still have the anxiety and lightheadedness and it’s been 2 weeks. I’m praying it goes away soon. I guess from taking so much this all happened bc I would take it once or twice a week and never experienced the feelings I got. Never taking another one again though."

1 / 10
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5 Report
  • Anonymous
  • Taken for less than 1 month
  • April 10, 2022

Norflex (orphenadrine) for Muscle Spasm "I can't say it has really made any difference. However, once I started taking 1x 100mg at night and 1x 50mg in the morning. My eye sight has been affected, my hands are shaking and my anxiety is next level. I also can't focus on any daily important tasks. I have herniated disks in my back, hip and knee pain issues."

2 / 10
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6 Report
  • Mama...
  • May 14, 2017

For Muscle Spasm "Given in ER for sciatica was wheeled in then walked out. First time can sit in chair in 2 weeks. I worry about blood pressure high but Dr says from pain no pain but normal pulse 65 to 80 now 105 to 109 was given norco for pain but get very sick can use Tylenol instead"

9 / 10
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14 Report
  • nurse
  • Taken for 10 years or more
  • June 20, 2017

For Migraine "Have been using orphenadrine for migraine for several years. I use 100mg ER tablet with 1000mg acetaminophen. It is the only thing that has consistently worked on my migraines without major side effects. It is inexpensive and nonaddictive but not used much in the US. I had suffered for years with migraines, had been on atenolol with some decrease in the number but it exacerbated asthma. I discovered this medication while living in the Philippines and it has been a lifesaver. Fortunately I have migraines only 2 to 3 times per month. I do not know how it would work with intractable migraines."

9 / 10
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14 Report
  • Freel...
  • Taken for 5 to 10 years
  • October 18, 2020

For Muscle Spasm "I was prescribed orphenadrine 6 years ago for neck spasms. Everything described here is accurate and the benefits were great. A week ago I decided to stop taking this because I no longer want to be dependent on a muscle relaxer."

9 / 10
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8 Report
  • Jano
  • Taken for 1 to 2 years
  • March 24, 2021

For Muscle Spasm "I have been thru every muscle relaxers and for me Orphenadrine has been the one that helps the best. It's an older medication and sometimes hard to find, and some insurance don't like covering it. But it's really worth the 30 bucks I pay per month."

10 / 10
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7 Report
  • Depaul
  • November 23, 2009

For Migraine "I was first given this medicine for intractable migraines at the Diamond Headache Clinic in Chicago. The headaches were so severe that I could not even lay my head on a pillow. After treatment with Orphenadrine Citrate 60mg IM every 6 hours. No more migraines. I maybe have to take it once a month. When they occur.....it takes care of them. This is adjunct emergency medicine I might add. They placed me on Verapamil 180 SA once a day and Keppra at night. So far so good. Headache free for the first time in over 15 months. My doctor there was great."

10 / 10
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22 Report
  • Jess
  • Taken for 1 to 6 months
  • January 21, 2021

For Muscle Spasm "I am so thankful these orphenadrine exist. For yeeears I have had neck and shoulder pain to the point of bad headaches! NOOOOOTHING made it better doc put me on 5mg lexapro after trying everything else, when taking lexapro on the lowest dose it is actually more of a pain reliever, took this but still got it in and off. One day I had very bad lower back pain and was prescribed Norgesic. OMG HEAVEN!!!!! Seriously! Changed my life. I am reading a lot about anxiety on here and I have had anxiety forever but I have to say this does not cause any anxiety for me... seems like it’s made it better so it’s odd about the anxiety... I have absolutely no side effects! Anyway it is a life saver for me xx"

10 / 10
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7 Report
  • Tessie...
  • Taken for less than 1 month
  • May 2, 2015

Norflex Injectable (orphenadrine) for Muscle Spasm "I received 60mg of norflex inter-muscular injection due to a pulled muscle in my shoulder blade around 3pm. About half an hour of receiving the shot I was very sleepy after getting home and slept for 6 hours, when I woke I had hives all over my body and went to the ER, where they gave me IV Benadryl and IV Pepcid ( some kind of steroid ) the rash dimmed a little so they sent me home with prescribed Epi pens, Benadryl, and a steroid. Got home around midnight and went to sleep after taking my meds, when I woke the next morning I was covered in hives again but twice as many, so I went back to the ER when they told me this could last up to 5 days. I'm on day 3 now my entire body feels all bruised with itchy hives. I'm not allergic to anything."

1 / 10
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14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.