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Megestrol User Reviews & Ratings (Page 5)

Brand names: Megace ES

Megestrol has an average rating of 7.3 out of 10 from a total of 135 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Megestrol

Commonly mentioned side effects
  • Mom...
  • Taken for less than 1 month
  • December 6, 2020

For Unintentional Weight Loss (Underweight) "So I started taking Megestrol 40 mg 5 mls one time a day to gain weight. No, I don't have cancer/AIDS/anorexia, I simply wanted to gain weight. So my OBGYN prescribed this horrible drug with all of these chemicals/side effects, and I've been bleeding ever since. Before taking it, my periods were normal and on time. Now I might have to get a blood transfusion because I've been bleeding for 10 days straight. I hate that I ever took this drug. I'm going to have a talk with her tomorrow, and it's not going to be pretty."

1 / 10
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  • Che...
  • October 7, 2020

For Anorexia "I am a 29-year-old female. I have been quite petite after having two kids (I nursed both). My metabolism is extraordinarily fast. Fast forward to a couple of years later, a doctor finally found something to help me—Megestrol! The year is 2020. I started taking this medicine in August. I was weighing 97 pounds, and I’m 5’2. It’s now October, and I’ve already gained 10 pounds. I’m 107! I also do weight training with my husband, so my weight isn’t fat—it’s lean muscle mass! This medication gives you a huge appetite, so eat in moderation and healthy. I encourage working out if you’re able. I may not appear “thick” like most women my age, but I have a very nice and toned body! The results are amazing! I notice the changes in my thighs, glutes, and arms. When I first started this, I did get occasional hot flashes and a slight feeling of nausea. Both subsided after a couple of weeks. Nothing unbearable. *My doctor gave me a 1 mL dosage, twice a day.*"

10 / 10
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3 Report
  • Mom...
  • Taken for less than 1 month
  • November 8, 2021

For Abnormal Uterine Bleeding "Started bleeding 2 weeks after taking it. It was like a little bit. It felt like I peed myself, and when I was able to go to the bathroom, it was all over my legs and running down. I was so glad that I was wearing black pants when it happened. It was a nightmare. Still currently on my cycle. Been on it 11 days and counting. These do not work. I was so excited not to have periods only for me to feel like something is wrong when nothing was. Just a heavy period that’s lasting more than 5 days."

1 / 10
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  • sil...
  • Taken for 2 to 5 years
  • January 6, 2023

For Abnormal Uterine Bleeding "I started taking it in 2019. I started out taking ten tablets a day, which was horrible for me. I can barely take a Tylenol. But I had been bleeding every two weeks, lasting two weeks. I thought I was gonna bleed to death. I had become anemic. My doctor prescribed it. It took a while to work. I have thickening of the uterine lining causing bleeding. I gained 20 lbs :( quick. But it stopped bleeding. But now it's raising my blood sugar. I can't have that. So back to the drawing board.:("

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 3, 2023

For Abnormal Uterine Bleeding "I was given megestrol 40 mg twice a day, on what should have been the 5th day of my period. Extremely heavy period, went to the emergency room on day two. I've been taking it for 3 days now. Still having pink/brown spotting. I don't know if this ever ends or what?"

5 / 10
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  • Onc...
  • August 13, 2018

For Unintentional Weight Loss (Underweight) "Megace is a medication that is similar to progesterone. It is given to people who continue to lose weight related to AIDS or other illnesses, e.g., anorexia. So it is used to help these people increase their appetite and weight and NOT to treat people with obesity and overweight!"

1 / 10
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  • bet...
  • Taken for 1 to 6 months
  • November 18, 2024

For Anorexia "I started taking megestrol in September, the liquid, 10 ml a day, and all I can say is wow. I had times when I didn't want to look at food, now I am taking this, I live in the kitchen. I am 5'0", weighing 76 lbs. I had no meat on my bones, now, after the medicine, I have thighs, stomach, and butt, and my cheeks on my face are plumped. I can see the weight coming. The only side effects are night sweats, urinating a lot, no periods for two months, and no sex drive, but I don't care because I love this medicine."

10 / 10
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  • Jvm...
  • Taken for less than 1 month
  • April 12, 2023

For Abnormal Uterine Bleeding "I'm curious if anyone has been tested for von Willebrand disease in light of experiencing abnormal bleeding and clots. It wasn't until years later, when my child was diagnosed with hemophilia, that I realized my prolonged bleeding wasn't normal. As it turned out, I have the gene for the disease in my family, and heavy bleeding is a sign of it. My hematologist and gynecologist are working together to find a solution, and DDP or other medications have helped to alleviate my symptoms. Testing for von Willebrand's disease has made a big difference in my diagnosis and treatment."

8 / 10
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  • JDT...
  • Taken for 1 to 6 months
  • December 5, 2024

For Unintentional Weight Loss (Underweight) "Gained over 30 lbs in one month. I've got a belly now, but started at 116 lbs and now I'm easily over 140 lbs. I take 3 teaspoons twice a day. Steroid-like side effects at first, but pass in 10 days of use or so. I'm hungry A LOT! I will eat now until nothing is left to eat. I spend more on food, but I feel so much better at a healthier weight. Good stuff."

10 / 10
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  • Anonymous
  • November 14, 2008

Megestrol for Abnormal Uterine Bleeding "For abnormal bleeding with no known cause, this medicine has been a godsend for me. Instead of having my period 365 days a year, I don't get any now."

10 / 10
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101 Report
  • Eld...
  • June 9, 2012

Megestrol for Unintentional Weight Loss (Underweight) "Oncologist ordered it for mom's stage 4 lung cancer symptoms. It did an amazing job increasing her appetite, which helped her keep weight on."

10 / 10
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74 Report
  • Iro...
  • September 6, 2015

For Unintentional Weight Loss (Underweight) "Was losing weight like crazy, too much weight. Doc put me on megestrol, gained 25 lbs in a month!! Still gaining weight. Love it."

10 / 10
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53 Report
  • mar...
  • November 16, 2009

Megestrol for Unintentional Weight Loss (Underweight) "I've used Megace to help with lack of feeling hungry, which results in poor protein intake. Megace keeps my hunger level at a point where I want to eat and can keep my weight and nutrition up."

9 / 10
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67 Report
  • Anonymous
  • December 28, 2008

Megestrol for Unintentional Weight Loss (Underweight) "My mum has leukemia. This medicine helped her when she wasn't eating."

10 / 10
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45 Report
  • myc...
  • August 17, 2010

Megestrol for Anorexia "Medication works great for short-term usage. Long-term usage can suppress your adrenal glands and suppress your hypothalamic-pituitary-adrenal axis."

1 / 10
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32 Report
  • Bre...
  • Taken for less than 1 month
  • July 27, 2014

For Hot Flashes "Stopped hot flashes resulting from taking Lupron for prostate cancer. Wonderful medicine."

10 / 10
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23 Report
  • Anonymous
  • October 17, 2008

Megestrol for Hot Flashes "This medicine worked really well for me for about 6 weeks, then gradually stopped working."

8 / 10
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33 Report
  • Nie...
  • Taken for 2 to 5 years
  • April 21, 2015

Megestrol for Anorexia "Very thin woman, age 58. My first experience with this medicine was excellent. Now the generic Megestrol does nothing for me. Went through 9 bottles with no weight gain."

10 / 10
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  • Jen...
  • Taken for 6 months to 1 year
  • February 7, 2019

For Abnormal Uterine Bleeding "Was on 20 mg twice a day after bleeding for 18 months, and it stopped. Until I was told to stop taking it."

10 / 10
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  • Yan...
  • Taken for less than 1 month
  • February 17, 2018

For Abnormal Uterine Bleeding "Excessive bleeding due to fibroids for 14 days. Went to my doctor, he gave me this medication. My bleeding stopped in 2 hours. I love this medication."

10 / 10
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15 Report
  • Bad...
  • Taken for 1 to 6 months
  • August 12, 2015

For Anorexia "Has helped me so much. I have gained 20 lbs in 6 weeks."

10 / 10
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19 Report
  • Anonymous
  • November 9, 2009

For Hot Flashes "I used this medication for over 15 years for very severe hot flashes. I had no side effects. I have recently stopped using it and have not had the hot flashes return."

9 / 10
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22 Report
  • Pam...
  • January 9, 2018

For Hot Flashes "Taking Luprin for prostate cancer, one side effect of the Luprin is hot flashes, using Megestrol to control hot flashes. It works for me, hot flashes reduced by 95%."

10 / 10
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  • Via...
  • Taken for 1 to 6 months
  • August 6, 2018

For Endometrial Hyperplasia "I do not need to gain weight, as a matter of fact, I was already overweight, and now I'm gaining even more. Can I take something that won't make me gain so much weight?"

2 / 10
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10 Report
  • Bet...
  • November 17, 2016

Megestrol for Unintentional Weight Loss (Underweight) "My insurance will not cover this medication for what I'm being treated for. I was prescribed this medicine for extreme weight loss."

2 / 10
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13 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.