Megestrol Alternatives Compared
| Megestrol | Medroxyprogesterone | Mirena |
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| Megestrol | Medroxyprogesterone | Mirena levonorgestrel |
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Prescribed for Abnormal Uterine Bleeding, AIDS Related Wasting, Anorexia, Breast Cancer - Palliative, Cachexia, Endometrial Cancer, Endometrial Hyperplasia, Hot Flashes. May also be prescribed off... View more |
Prescribed for Abnormal Uterine Bleeding, Amenorrhea, Birth Control, Endometrial Hyperplasia - Prophylaxis, Endometriosis, Endometrial Cancer. May also be prescribed off label for Gender Dysphoria... View more |
Prescribed for Abnormal Uterine Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Choose a suggestion below Abnormal Uterine Bleeding
Popular Comparisons
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| More about Megestrol | More about Medroxyprogesterone | More about Mirena (levonorgestrel) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Megestrol has an average rating of 7.4 out of 10 from a total of 122 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 19% reported a negative effect. |
Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2336 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 51% reported a negative effect. |
Mirena has an average rating of 6.1 out of 10 from a total of 2476 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full megestrol side effects document. |
See the full medroxyprogesterone side effects document. |
See the full Mirena side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all megestrol prices |
View all medroxyprogesterone prices |
View all Mirena prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Megace ES | Depo-Provera, depo-subQ provera 104, Provera | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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20 hours |
401 hours |
45 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 140 drugs are known to interact with megestrol:
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A total of 214 drugs are known to interact with medroxyprogesterone:
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A total of 224 drugs are known to interact with Mirena:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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August 18, 1971 |
June 18, 1959 |
December 06, 2000 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.