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Megestrol Dosage

Applies to the following strength(s): 40 mg/mL ; 20 mg ; 40 mg ; 625 mg/5 mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Breast Cancer-Palliative

Megestrol tablets are indicated for use in the palliative treatment of advanced carcinoma of the breast: 160 mg/day (40 mg of oral tablets four times a day)

Usual Adult Dose for Endometrial Carcinoma

Megestrol tablets are indicated for use in the palliative treatment of advanced carcinoma of the endometrium: 40 to 320 mg/day of oral tablets in divided doses

Usual Adult Dose for Anorexia

Megestrol oral suspension is indicated for use in the treatment of anorexia at a dose of 800 mg/day.

Alternatively, 625 mg/5 mL of the concentrated formula (Megace ES formula) may be given.

Note: 800 mg/20 mL of the regular formula is equivalent to 625 mg/ 5 mL of the concentrated formula.

Usual Adult Dose for Cachexia

Megestrol oral suspension is indicated for use in the treatment of cachexia at a dose of 800 mg/day.

Alternatively, 625 mg/5 mL of the concentrated formula (Megace ES formula) may be given.

Note: 800 mg/20 mL of the regular formula is equivalent to 625 mg/ 5 mL of the concentrated formula.

Usual Adult Dose for Weight Loss

Megestrol oral suspension is indicated for use in the treatment of unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS) at a dose of 800 mg/day.

Alternatively, 625 mg/5 mL of the concentrated formula (Megace ES formula) may be given.

Note: 800 mg/20 mL of the regular formula is equivalent to 625 mg/ 5 mL of the concentrated formula.

Usual Adult Dose for Abnormal Uterine Bleeding

5 to 10 mg/day for 5 to 10 days

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

A minimum of two months of continuous treatment is considered to be an adequate period for determining the efficacy of megestrol tablets.

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