Megestrol and Night Sweats: What Users Say

• Jay...
• April 24, 2016

For Abnormal Uterine Bleeding "I had heavy bleeding for several years, but within the last 3 years, I ended up in the hospital twice, in which I had to get several blood transfusions. I have only 1 fibroid, the size of a dime. I've had a DNC and ablation surgeries. I was prescribed megestrol in January after leaving the hospital. I was told to take 2 pills a day instead of 4. In February, when my menstrual came on, it has not gone off since, even though it is light. So I was told to take 4 a day, no change. I am getting tired of wearing pads every day. The side effects are some mood swings, every night, about 3 times, I wake up drenched in sweat. I've gained over 20 lbs. I really do not want a hysterectomy, but it seems I have no choice."

• Lio...
• October 30, 2016

For Abnormal Uterine Bleeding "I started taking this medication for heavy bleeding. I was having periods that lasted 9 - 10 days, it went to 2 weeks, then 3 weeks, now a month and counting. I noticed that when I skipped a dose or two, the bleeding decreased. So I did some research and found that one of the side effects was increased bleeding. I also had night sweats and felt thirsty all the time, like I was dehydrated. An ablation has been recommended, but now I'm not sure if it's needed due to the side effects."

• Coi...
• Taken for 6 months to 1 year
• December 12, 2018

For Anorexia "I'm a male in my 30s. I've always been skinny, but when I got down to 104 lbs (at 6 feet tall), I started getting scared. My doctor prescribed Megace to help give me an appetite. After about 3 months, I was up to 120 lbs. It doesn't give me cravings; I simply find myself eating more. In my case, there's only been one real side effect, and that's been night sweats, which can get fairly bad at times. They don't happen every night, but sometimes it will happen multiple times and wake me up during the night. For males, it can affect sex drive, but that hasn't really been an issue for me, thankfully."

• Kat...
• August 6, 2016

For Endometrial Hyperplasia "Began taking this medication in April and still on it in August. I was bleeding heavily for 5 months. A biopsy revealed hyperplasia with atypia. This medication stopped my period but gave me intense night sweats, headaches, breast pain, and weight gain. I'll be having a hysterectomy in September."

• bet...
• Taken for 1 to 6 months
• November 18, 2024

For Anorexia "I started taking megestrol in September, the liquid, 10 ml a day, and all I can say is wow. I had times when I didn't want to look at food, now I am taking this, I live in the kitchen. I am 5'0", weighing 76 lbs. I had no meat on my bones, now, after the medicine, I have thighs, stomach, and butt, and my cheeks on my face are plumped. I can see the weight coming. The only side effects are night sweats, urinating a lot, no periods for two months, and no sex drive, but I don't care because I love this medicine."

• Ree...
• February 11, 2021

For Hot Flashes "It causes really bad night sweats!!!! OMG, but it works very well for a weight gainer."