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Megestrol User Reviews & Ratings (Page 4)

Brand names: Megace ES

Megestrol has an average rating of 7.4 out of 10 from a total of 131 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Megestrol

  • Abnor...
  • September 12, 2021

For Abnormal Uterine Bleeding "I have suffered with abnormal uterine bleeding for 3 years, I had a cyst removed in March the doctor said that was the problem within a week of the surgery the bleeding came back. I was put on megestrol until I can have my hysterectomy it stopped the bleeding instantly for 2 days but it came back today heavy to the point I’m changing my pad every hour. I’m so fed up with this and actually looking forward to surgery so I can get my life back"

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  • QUETPYE
  • June 16, 2017

For Abnormal Uterine Bleeding "I was prescribed the medication for relief of heavy bleeding during my period due to fibroids and adenomyosis. The 1st and 2nd months were wonderful! I took it the first day of my cycle until the end of my cycle. It actually stopped the bleeding completely. After the 2nd month, I had some spotting and my blood pressure elevated. I stopped taking it after my cycle and my pressure went to normal. I started spotting that increased over time and resumed but had to stop because I realized it raised my blood pressure. I've now been bleeding for 2 weeks and had to go on amlodipine to lower my blood pressure because it has not gone down."

9 / 10
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  • Nogains
  • Taken for less than 1 month
  • January 2, 2020

For Unintentional Weight Loss (Underweight) "I was put in 40 mg of megestrol a day for being underweight and having no appetite. I desperately wanted to gain weight (I’m 5’2” and 85 lb) today is day 18 of taking this drug and I have experienced no change in my appetite whatsoever. I’m still giving it 10 stars because technically weight gain is not the purpose of the drug. My side effects were headache and chest pain the first week which went away and extreme thirst at night and some light gas. Really bummed I couldn’t gain any weight on it though."

10 / 10
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  • Katydid
  • August 6, 2016

For Endometrial Hyperplasia "Began taking this medication in April and still on it in August. I was bleeding heavily for 5 months. A biopsy revealed Hyperplasia with atypia. This medication stopped my period but gave me intense night sweats, headaches, breast pain and weight gain. I'll be having a hysterectomy in September."

6 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 18, 2018

For Anorexia "I’ve been skinny all my life.. I’ve tried different supplements and medications to try to gain weight. Most of them put me to sleep and I didn’t want that. My physician prescribed me 40mg megestrol.. when I first went to the doctor I weighted in at 100lbs even. After 3 weeks I’m already 8lbs heavier. I want 22 more pounds though. Haven’t had many side effects so I’m going to rate it at a 9 until I gain my full 30lbs."

9 / 10
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  • krista
  • Taken for 1 to 6 months
  • May 20, 2023

For Abnormal Uterine Bleeding "I had a D&C in January 2023 and they found 4 polyps on my uterus lining and a lot of thickness. I was prescribed this medication beginning of February. My ob-gyn put me on megestrol 40mg 4 times a day due to endometrial hyperplasia. Starting on March 21, 2023, I started bleeding so I came off the medication due to my obgyn said I shouldn't be bleeding any. Well, I go into the office in April and he wants another D&C and told me this should stop the bleeding. Well, I had the D&C 2 weeks ago, and guess what? I am bleeding worst than I had ever bled. With clots and extreme cramps and heavy bleeding. I honestly think this medication has messed me up big time. I have been bleeding for 2 months and my ob-gyn still doesn't understand why I am bleeding. He said I shouldn't be bleeding at all. All he can say is I am a special case and prescribed the same medication again for another 3 months and I am not going to take it again!! Bad side effects!"

1 / 10
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  • Coinman
  • Taken for 6 months to 1 year
  • December 12, 2018

For Anorexia "I'm a male in my 30s. I've always been skinny but when I got down to 104 lbs (at 6 foot tall), I started getting scared. My doctor prescribed Megace to help give me an appetite. After about 3 months, I was up to 120 lbs. It doesn't give me cravings; I simply find myself eating more. In my case, there's only been one real side effect and that's been night sweats which can get fairly bad at times. They don't happen every night, but sometimes it will happen multiple times & wake me up during the night. For males, it can affect sex drive, but that hasn't really been an issue for me thankfully."

8 / 10
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  • Mommy
  • Taken for less than 1 month
  • December 6, 2020

For Unintentional Weight Loss (Underweight) "So I started taking Megestrol 40mg 5 mls one time a day to gain weight. No I dont have cancer/AIDS/Anorexia I simply wanted to gain weight. So my OBGYN prescribed this horrible drug with all of these chemicals/side affects and I've been bleeding every since. Before taking it my periods were normal and on time. Now I might have to get a blood transfusion because I've been bleeding for 10 days straight. I hate that I ever took this drug. I'm going to have a talk with her tomorrow and it's not going to be pretty.."

1 / 10
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  • Amber
  • Taken for 1 to 6 months
  • May 10, 2015

For Abnormal Uterine Bleeding "Given magestrol 40 mg twice a day after D&C. I started bleeding after 45 days of using it, weight gain, too much anger. Even my hair started falling out..very bad experience with it. Doctor gives me progesterone 200 mg and still after taking it since 9 days bleeding is still on. I don't know when will this stop but I have the progesterone for 14 days and then stop it and see what will happen !"

7 / 10
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  • PAano
  • July 29, 2020

For Endometrial Hyperplasia "I have been struggling with endometrial hyperplasia for about 5 years now. This is my first time sticking to my recommended dosage because my husband and I are trying to conceive. I definitely have cravings and find myself eating and not even hungry so it has been important for me to really get a grip on it and try intermittent fasting. My weight is a main cause of my condition I believe. Other symptoms I have experienced are very light, mild vaginal cramping. Usually like a throbbing feeling. This may happen randomly for a moment and then I might not feel anything for days. Some pelvic and abdominal cramping but again faint and not often. I have a few days of old blood discharge after my first month, 1 day of spotting into the 2nd month. Going into month 3 now. Im taking 40mg 2x a day and have a D&C at the end of Aug to follow up."

6 / 10
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  • Tee...
  • Taken for less than 1 month
  • August 26, 2021

For Abnormal Uterine Bleeding "Started taking megestrol in July for heavy menstrual cycles. When I first started taking it I thought...wow this is my miracle drug, stopped the heavy bleeding to almost nothing. That took place for about 3 and a half weeks, I then noticed I had been on my menstrual all that time. The 4th week while still taking megestrol I had the biggest blood clot! I was like omg!!! After that is slowed back down but I still get blobs of blood. And did I mention I have been on menstuating 57 days and counting before megestrol the longest was 22 days My doctor didn't seem shocked. I have been begging for a hysterectomy! I had to take megestrol for a month first Second get a D & C Then they will see if insurance covers surgery Omggggg I have no life"

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  • Kaykay
  • July 6, 2021

For Abnormal Uterine Bleeding "I’m 24 years old, been bleeding for 3 1/2 months, just got prescribed this pill on Thursday and today is Tuesday and I only stopped bleeding for one day and my bleeding hasn’t changed at all It’s actually gotten a tad bit heavier. Idk what to do, my gyn told me it’ll take 2-3 days to stop and it’s going on day 5 of taking this pill. I'm a tad bit worried because it took me literally 2 months to even be seen by my gyne because it was so backed up."

2 / 10
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  • Tammy...
  • September 24, 2017

For Abnormal Uterine Bleeding "I was bleeding very heavy, I could soak through a super plus tampon and a huge after pregnancy pad within minutes. I was passing clots so big they wouldn’t fit down the shower drain. My doctor put me on 40mg of Megestrol 1x a day over 3 months ago, so far I had 2 days in a row of light spotting. I love this stuff!!!! I’m actually taking this instead of getting a full hysterectomy. My only concern is I had laparoscopic gallbladder surgery about a week ago and I’ve had some pretty intense uterine pain with heavy bleeding and blood clots since. I stopped taking the Megestrol for a few days thinking nature would run it’s course, I started taking it again and the uterine pain started back up. I hope this surgery didn’t wreck Megestrol for me."

10 / 10
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  • Luna
  • Taken for 1 to 6 months
  • December 9, 2020

For Endometrial Cancer "I had an oophorectomy due to a tumor on one ovary and had lost so much weight and could not eat or function properly. I had increased anxiety, insomnia, and no appetite. Megace helps me sleep and I eat normally while I'm on it. It has helped me gain almost 15 pounds in three months of being on it with regular sleep and no cysts/tumors! Truly saved me!"

10 / 10
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  • LMD
  • Taken for 1 to 6 months
  • December 9, 2019

For Endometrial Hyperplasia "This is my story, had failed IVF. Abnormal uterine bleeding from the last miscarriage, on and off menstrual period, not heavy at all. I technically not ovulating and rarely menstruate. June 2019, I went to see RE for water ultrasound to R/U polyps, and yes my suspicious was right. Polyps removed, found advanced hyperplasia grade 1, placed on Megace 160mg daily. First month, October 2019, no bleeding, second month November, started spotting, and I called my doctors and was told it was normal. Until today, 12/9/2019, I am spotting. No heavy flow or clots. I read an article that this medication regulates period of there was amenorrhea but for those who are menopausal. So, now I am unsure at my age of 42, I am menopausal. I am very confused"

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  • Oncol...
  • August 13, 2018

For Unintentional Weight Loss (Underweight) "Megace is a medication that is similar to progesterone. It is given to people who keep to losing weight relating to Aids or other illness eg anorexia. So it is used to help these people increase there appetite and weight and NOT to treat people with obesity and overweight!"

1 / 10
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  • RayJM
  • November 29, 2016

For Unintentional Weight Loss (Underweight) "After stopping the megestrol yesterday after 2 months due to loss of weight during suspected lung cancer I have had continual very loose bowel movements so far all day the following day. Is this a side effect of coming off the medicine.. If anyone else has had this experience I would like to know about it as I didn't see this as a side effect in the literature"

10 / 10
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  • skinnim
  • Taken for 1 to 6 months
  • March 9, 2018

For Anorexia "I have always been a small girl, never weighing over 100lbs even in my early twenties. Two years ago I went through a depression and lost so much weight and barely had an appetite. My primary care doctor prescribed this medication and It really helped. My appetite picked back up. I went from eating one meal a day to eating all 3 meals a day plus snacks. I went from 100 to 125 in about two months. After I finished the bottle I went back down, but was able to maintain a fair weight of 115lbs. It's good for any person struggling to have an appetite and to gain weight. However, side effects for me included: no period, too many bathroom runs(especially during the night), and gas! Other than that I am happy."

10 / 10
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  • Momma...
  • Taken for less than 1 month
  • November 8, 2021

For Abnormal Uterine Bleeding "Started bleeding 2 weeks after taking it. It was like a little bit. It felt like I peed myself and when I was able to go to the bathroom it was all over my legs and running down. I was so glad that I was wearing black pants when it happen. It was a nightmare. Still currently on my cycle. Been on it 11 days and counting. These do not work. I was so excited not to have periods only for me to feel like something is wrong when nothing was. Just a heavy period that’s lasting more than 5 days."

1 / 10
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  • Pee
  • Taken for 1 to 6 months
  • April 24, 2018

Megace ES (megestrol) for Anorexia "I have picked up some weight, not as fast and I hoped and I don't really see the results in my body weight, but the scales read different. I have increased my appetite but is very full feeling and bloated"

6 / 10
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  • Faith
  • Taken for less than 1 month
  • August 7, 2021

For Abnormal Uterine Bleeding "I'm 29 and hope this works. Bleeding for months at a time, no energy or appetite has really been draining. It is day 2 of the 40mg once a day. I felt great for the first time in a while. Was able to get out of bed, cook and do a little grocery shopping. Not feeling 100% yet, I'm just grateful for any improvements right now."

8 / 10
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  • SNicole
  • March 15, 2021

For Endometrial Hyperplasia "I have been taking this for about 2 weeks for hyperplasia with atypia. I had not really had any side effects until last night when I begin to have these awful leg cramps that made my legs feel tight and weak. My heart begin to race, I couldn't sleep (insomnia), and I just started feeling overall bad. I sent my doctor a message and awaiting a response. If these are the side effects, I don't know if I can continue these meds. I am supposed to take 40mg once per day for 3 months."

1 / 10
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  • Still...
  • Taken for 1 to 6 months
  • September 25, 2017

For Endometrial Hyperplasia "I was diagnosed with complex endometrial hyperplasia with atypia on 8/9/17 and began megestrol on 8/12/17. I slowly began experiencing common symptoms such as weight gain and increased appetite, but then I slowly started experiencing increased mood swings, irritability, insomnia, itchy body, and shortness of breath. What made me finally call the doctor on 9/19/17, was me being up at 3am with the inability to breath. I was informed to discontinue due to allergic reactions. On 9/21/17 I began with joint pain and swelling on my hands and wrists. By Friday, 9/22/17, I couldn't function for myself at all. My entire left arm and both hands were useless and I ended up in the ER where I learned this is all allergic reactions as well."

1 / 10
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  • Cheeks
  • October 7, 2020

For Anorexia "I am a 29 year old female. I have been quite petite after having two kids (I nursed both). My metabolism is extraordinarily fast. Fast forward to a couple years later, a doctor finally found something to help me— Megastrol! The year is 2020. I started taking this medicine in August. I was weighing 97 pounds and I’m 5’2. It’s now October and I’ve already gained 10 pounds. I’m 107! I also do weight training with my husband, so my weight isn’t fat— it’s lean muscle mass! This medication gives you a huge appetite, so eat in moderation and healthy. I encourage working out if you’re able. I may not appear “thick” like most women my age but I have a very nice and toned body! The results are amazing! I notice the changes in my thighs, glutes, and arms. When I first started this, I did get occasional hot flashes and a slight feeling of nausea. Both subsided after a couple of weeks. Nothing unbearable. *My doctor gave me 1Ml dosage, twice a day.*"

10 / 10
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  • Butte...
  • Taken for less than 1 month
  • October 31, 2021

For Anorexia "I was told to try this because I’ve tried everything under the sun and hate that I always am tired or sleepy after trying the things I’ve tried so I said heck I’ve tried everything else why not 1 more lol and to my surprise after being 100lbs most of my adult life I can say I’ve been taking this liquid for 3 weeks straight 10ml mornings and 10ml nights and today October 31st 2021 I’m now 118lbs. I’ve gained 10lbs because I started off 107/108lbs. I have an appetite all thru the night I love it lol because I barely had an appetite. I eat cereal, sandwiches, oatmeal etc you name it I want it. lol but this meds is a miracle worker TRY IT"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.