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Lupron User Reviews & Ratings (Page 3)

Lupron has an average rating of 6.9 out of 10 from a total of 31 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Lupron

  • Laney...
  • December 28, 2016

For Uterine Fibroids "I am on a 3 month shot plan but monthly shots. I didn't want the 3 month all at once because I wanted to see how my body would react to it first. Shot given 12/07/16 and today is 12/28/16. The first week, I didnt really have any side effects and I was really hopeful that this will be the worse. Wishful thinking didnt last long. Hot flashes, night sweats, chills, emotional wreck and I believe slight headaches that come and go. BUT on the contrary, less than a month and my fibroid has already physically shrank. I havent seen the doc yet but I can physically see that it shrank. My clothes are loose in the belt line area. My fibroid was the size of a small grapefruit (17cm) but I really see a huge different in shrinkage. Could be worse :/"

5 / 10
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  • Az-bob
  • Taken for 1 to 6 months
  • May 29, 2020

"My prostate cancer was treated with radiation in 2003 but came back around 2013 and PSA has climbed all the way to 14.8 now in 2020 so thought it was time to try something. Lupron gave me horrible side effects including severe hot flashes about 2 every hour 24/7, nausea, dizziness, tiredness, weight gain, constant urination, very low libido, etc. On the positive side I only had one 3 month shot and my PSA went from 14.8 down to 0.3 however I am not going to take another shot and will see how it goes. Will try to eat and exercise better."

3 / 10
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  • Miss...
  • July 12, 2015

For Endometriosis "I've been on lupron twice in 6years. The first time was 2008 & I didn't experience any symptoms. I was extremely happy about that. Like most of you reading all the side effects had me a little on edge. The second time my doctor suggested that I get on it (Dec2014) I agreed with no problem.. Hoping that will be the same experience as the first time.... Ohhhhhh but it wasn't, I had hot flashes, night sweats & weight gaining. I couldn't wait until those 6months were over.. Unlike the first time 3 months off lupron my cycle started & 2weeks later two cyst 7.5cm... I was devastated & in so much pain & b4 you knew it I was having surgery.. I'm 2days fresh out the hospital on lupron again... I pray this time I have a different outcome."

9 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • November 24, 2015

For Uterine Fibroids "Received a 3 month injection 8/20 for heavy bleeding due to fibroids. Did not stop bleeding/spotting until middle of October. Now I need another dose and the price jumped from $10 (promo fee) to $1,100- $3,000. Needless to say I cannot afford the next round. Also had a headache for full 3 months. However, my doctor said it did shrink my fibroid enough to get the ablation I need."

4 / 10
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  • Sandr...
  • Taken for less than 1 month
  • October 2, 2012

For Female Infertility "EXTREME HEADACHES!! Lupron - I started the medication 5 days ago and starting on day 3 I began getting really bad headaches and it doesn't seem to ever go away. I cannot take Advil so I'm not sure if that would help. I tried taking a nap but I wake up and it's still there. Never had this problem before so I'm certain it's the Lupron. Other than that I have no other complaints."

9 / 10
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Are you taking this medicine?

  • Nicole
  • Taken for 1 to 6 months
  • February 18, 2020

"I was given Lupron depo for my Endometriosis. My husband and I had been having issues having a baby. I was suppose to have 3 shots total. After the first shot it wrecked me. It messed with my bowels, my period was more painful than ever, body pain, insomnia and extreme fatigue, one night I had to call 911. My skin was burning from the inside out and my heart started reaching to the point where I could barely breath and my heart was palpitating. I refused the next 2 shots. Since then I've continued to have bone and joint pain, fuzziness, I can't retain thoughts or remember simple words. My teeth became really sensitive. It caused nothing but hardship."

1 / 10
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  • Chris...
  • Taken for less than 1 month
  • March 23, 2023

"This did not work. I was supposed to take it for 3 months, but one dose in, and the side effects outweighed the possible payoff. I experienced an increased sex drive (the opposite of the listed side effects), anxiety (still there 10 months later), and other mental health problems. Lost my period but not until 2 months after the injections and then it became hit or miss for several months. The worse decision I ever made was trusting a doctor who suggested this."

1 / 10
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More FAQ

  • 9 years
  • Taken for 6 months to 1 year
  • December 1, 2022

"Was diagnosed 9 years ago PSA 29. Had prostate removed in 2013 then PSA went up again so had 37 radiation treatments. PSA started to rise again and after 7 years went up to 8.4. Started Lupron February 2022. PSA dropped to 0.3 which is good. Unfortunately side effects eliminated sex life and now very week/fatigued so makes any exercise difficult and painful. Feet and legs hurt a lot when a hot flash starts which happens up to a few times per hour, 24/7. This wakes me up all night. I guess I shouldn't complain as it is probably keeping me alive. I get 3 or 4 month shots."

7 / 10
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  • Gail
  • Taken for 1 to 6 months
  • November 11, 2019

"I am 30 yrs old when I first discovered that I have a 6.9cm uterine fibroid from my ultrasound, since I am 2 months pregnant. I feel like my fibroid is getting bigger as I bear my baby. After a month. I had a miscarriage. My ob told me that it was because of my fibroid. So this March after my first period She gave me the first shot of lupron. I didn't feel any pain in my abdomen until last shot this August. Hoping that the medicine would at least make the size of the fibroid would be 50% smaller. Unfortunately, my fibroid gets an inch bigger from 7.8 to 8.9cm The next step now is myemectomy since I still want to have babies in the future. Until now (Nov) I don't still have my period. I am very much worried. The Ob says that my period will be back 2 months after my last shot but up to now, I don't have my period. I'm beginning to feel abdominal pain again like the feeling of having your first day of menstruation almost 3 weeks already. Please advise me what is my next step."

4 / 10
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  • 1968gto
  • Taken for 2 to 5 years
  • February 26, 2013

For Prostate Cancer "I have been on Lupron for two years. I got my last shot in December. It has kept my PSA under .03. Can't wait to see if it is still that low after 3 months! You learn to live with the side effects."

10 / 10
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  • DonAl...
  • March 30, 2009

For Prostate Cancer "While I do believe it has lengthened by life, the side effects are difficult to deal with. I am extremely sun sensitive, also have a rash on my wrists that doesn't go away. "

8 / 10
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  • Tom...
  • June 16, 2016

For Prostate Cancer "Been on this drug 15 months No libido at all day sweats night sweats and hot flashes irritability and erratic memory episodes PSA from 30 to .01 after radiation and continues today"

5 / 10
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  • Annie
  • September 10, 2014

For Endometriosis "Third shot of Lupron and suffering a lot. Joint pain and depression. But doctor does not agree it has side effects."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 28, 2014

For Endometriosis "So far not any significant changes. Still feel terrible, back pain, legs ache, upset stomach. "

2 / 10
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  • Lynne
  • Taken for 6 months to 1 year
  • April 12, 2019

"The only thing I regret in my life is taking Lupron for Endometriosis. This is a very dangerous and life changing drug. Led my organs to shut down, infertile and had a total hysterectomy at 34."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.