Lupron User Reviews & Ratings

• ols...
• September 17, 2014

For Prostate Cancer "Had my first Lupron shot before 45 days of radiation. Having hot flashes, muscle and joint pain but not too bad. Doing the shot every 3 months. PSA went from 11.5 to 0.1. Next shot coming up in a couple of weeks. Don't have a problem with the shot or after having it. I think Lupron has been helping me, but everyone has different experiences with it. Good luck to all you prostate cancer people."

• Con...
• Taken for 2 to 5 years
• October 2, 2013

For Prostate Cancer "Have been on Lupron for about 2 years, and my stage 4 prostate cancer is now in remission. My prostate cancer specialist gets all the credit and kept side effects to a minimum with the help of other meds and supplements. I recommend Lupron."

• wal...
• Taken for 5 to 10 years
• March 5, 2014

For Prostate Cancer "I was 50, had my prostate removed then let it go at 55. Had a PSA above 400, my weight dropped to 105lbs thought I was going to die then had 15 radiation treatments and started Lupron shots. PSA dropped, I came back to life. Now I'm 63 still getting Lupron shots every 6 months. Sure there are some side effects but it's better than being dead if you have cancer. I hope something works for you."

• cla...
• December 10, 2009

For Prostate Cancer "I have been receiving Lupron or Eligard every 6 months for ten years to help reduce the growth of prostate cancer. Early research reports indicated that one side effect might be peripheral neuropathy. That started to develop in my feet shortly after I was put on Lupron. Loss of bone mass has also been associated with Lupron. I have begun taking 1200 units of calcium Vitamin D each day. My PSA scores have all continued to be below 0.1. I have no major complaints, and have learned to live with the side effects."

• mdo...
• January 4, 2012

For Prostate Cancer "Had 1st shot 11/10/11, PSA was at 182, tested 3 weeks later, PSA had dropped to 3.3. Have prostate, metastatic bone and lymphatic cancer. This combined with radiation therapy, greatly improved my mobility (pelvis, hips fully involved, as well as on and inside spine). Side effects are hot flashes and night sweats, but other than that manageable for the relief I've gotten."

• WWI...
• Taken for 6 months to 1 year
• February 18, 2015

For Prostate Cancer "Have been getting monthly Lupron 7.5 mg injections since July 2014 (just had my 8th injection). No hot flashes; some mood swings and I recently started having arm and leg cramps a few times a week. Taking Casodex 50 mg daily as well, so it's hard to know which to blame. PSA was 205 when I started these meds and is now 0.03. I believe the complete lack of hot flashes may be due to receiving the monthly vs 3 or 6-month injection dose. I hope this information helps others."

• Rus...
• Taken for 2 to 5 years
• February 6, 2015

For Prostate Cancer "Prostate removed - huge 350 cc - Gleason 7, PSA 15, radiation for 8 weeks, Lupron every 3 months for one year, every 6 months for the next year and a half. PSA has been less than 0.01 since initial radiation. Weakness, memory problems, and hot flashes but no cancer. Treatment is worth the side effects. I feel very lucky."

• Anonymous
• June 11, 2012

For Prostate Cancer "My cancerous prostate was removed when I was 65, 6 years ago. I receive a 22.5 mg Lupron injection about every 3 months. My PSA decreases each time from about 2 to undetectable. The injection area is sore for 2-3 days after each injection. I have perhaps a dozen relatively minor hot flashes daily. I take 4 venlafaxine HCl 75 mg tablets daily to curtail hot flashes."

• ble...
• Taken for 1 to 6 months
• December 18, 2012

For Prostate Cancer "I got this shot about two years ago. I was told by the urologist that it was a one-month shot. I had the shot because we wanted some time to research and decide what treatment would be best. Found out later that it was a 3-month shot! Suffered severe side effects! PSA dropped from 13 to 7, but the side effects were NOT worth it! Hot flashes, with some of them causing me to nearly pass out, were often (20 a day), memory problems, muscle/joint pain, and on and on! Once, while teaching, I suddenly didn't know where I was or what I was doing! After radiation, I was recently put on Trelstar on a MONTHLY basis, nearly the same side effects but NOT the really bad ones!"

• Mik...
• October 18, 2011

For Prostate Cancer "Got a shot of it on Friday, some soreness on Saturday; but saw immediate results of reduced urgency to void every hour, sometimes 4-5 times per hour, depending on consumption of liquid. Some sensitivity to the right side of the groin and scrotum. Seemed like it might be some blockage in semen tubing or possibly the medication impacting the two lymph nodes that showed some cancer invasion. Now it is Tuesday evening, and the sensitivity on the right side of the groin is minimal. It is really amazing how fast the medication impacted the symptoms. I got a 3-month shot and expect to do a blood draw in 6 weeks to evaluate the impact on the PSA levels. So far, so good."

• Mr ...
• October 26, 2016

For Prostate Cancer "Diagnosed with stage 4 PC in my right hip. PSA for years was between 2.0 to 3.5. Went from 3.5 to 29 in one year! I encourage all with a PSA of over 3.0 to get a bone density test! Started Lupron 30-day shot on July 5th, 2016. First 3 months went from 29 to 3, so heading in the right direction. Bone pain reduced after the first shot by more than 75%. Hot flashes around the clock, roughly 10 to 12 a day with an intensity level of about a 5 or 6. Very annoying but tolerable. Miscellaneous aches and pains in joints and muscles. Occasional fogginess and definitely wake up too much to pee. I'm trying Flomax now, I hope to see some improvement. Fatigue is real! I can't tell if this is harder on my family than me! So far, so good. God bless to ALL!"

• Anonymous
• April 18, 2011

For Prostate Cancer "Second injection started night and day sweats. This has increased to every 2-3 hrs during the day - less frequency at night. Dropped my PSA from 30 to 0.07 post-prostate removal. Time on medication: 6 months."

• Len...
• July 13, 2016

For Prostate Cancer "Eight months into Lupron plus Casodex, and I am refusing the next three-month shot. PSA went from 5.7 to 0.2 to 0.1, and I am just finishing up nine weeks of radiation. GL scores were mostly 9's, but no metastatic found. To say a less common side effect is loss of libido is just plain BS. About a month after the first shot, I was done with sex. The doctor said once the testosterone is gone, that's normal. Little aches and pains linger, my testicles shrink, I lost all hair under my arms and it's slow-growing elsewhere. Sometimes I seem to be in a fog mentally. Hot flashes like you wouldn't believe until they offered me other meds, which help somewhat. I put on five pounds of blubber below the belly. Lack of energy as well. It works, but I think doctors keep you on it too long for stage 1 or 2 cancers."

• Inl...
• December 30, 2011

For Prostate Cancer "Recently received my first Lupron injection. Within one week my PSA dropped from 69.7 to 11. I have not noticed any severe side effects as of today. I am also starting Alendronate Sodium tablet for healthier bones."

• Anonymous
• April 10, 2011

For Uterine Fibroids "Side effects experienced from 3-month shot: hot flashes, night sweats, fatigue, cognitive 'fuzziness', decreased memory. I experienced a significant temporary reduction in fibroid size/abdomen size (pre-surgery)."

• Nis...
• August 5, 2016

For Prostate Cancer "Diagnosed Stage 4 prostate cancer-July 2012-PSA=8. Radical prostatectomy-October 2012-PSA=0.6. Forty days of radiation-April 2013-PSA=0.1. PSA=0.3-Jan 2015. PSA=1.0-March 2015. First Lupron injection-April 2015-PSA=0.1. Second Lupron injection-Oct 2015-PSA=0.1. Third Lupron injection-April 2016-PSA=0.1. Fourth Lupron injection-Oct 2016-PSA=???. Lupron injections accompanied by daily tablets of Bicalutamide. Side effects: penis shrinkage (afraid it will soon disappear), libido absent, hot flashes, some insomnia, increased neuropathy, some itching, inflammation in hands, extreme fatigue. All side effects manageable-beats being dead-and has allowed me time to tie up loose ends and who knows-I may have years ahead!"

• tup...
• August 30, 2016

For Prostate Cancer "I am 87 and have been treated with Lupron for about 6 years. I just had a checkup, and my PSA level was .430. My last shot was in April. It is hard to tell when I will have another shot, I will check in with my doctor in four months. So far, the only side effect is the hot flushing. It is fairly regular, lasts about 45 seconds or so, and is a bit annoying, but considering it is keeping the cancer at bay, I can live with it."

• alb...
• Taken for 1 to 6 months
• May 7, 2016

For Prostate Cancer "This is pure poison. I have very bad side effects from this poison, and the doctor said he can do nothing. The physical and mental pain is so bad: hot flashes, very high blood pressure, headaches every day, pain urinating, joint pain, mental confusion, brain fog, memory loss, totally itchy all over, sleeplessness, very bad fatigue, and a lot more. My doctor never told me anything about this poison, just injected me with a 6-month supply at $6,000.00."

• Gru...
• September 30, 2016

For Prostate Cancer "My PSA was rising after RP to 0.59. Started radiation with Lupron. If you exercise really hard with lots of caffeine, no sugar in the morning and minimal sugar all day long with high-quality food, then the effects of Lupron are minimal other than the muscle pain and some joint pain. Sex life is about once a month. The more you exercise, the more likely you are able to have a sex life. After six months on Lupron, I can still have sex. I took Bicalutamide with my first shot. I highly recommend avoiding the hot flashes."

• Fly...
• Taken for 5 to 10 years
• January 13, 2017

For Prostate Cancer "At age 60, biopsy showed prostate cancer, PSA was 10. Had it out. After it was out, PSA was still ten. Started Lupron, and PSA dropped to 0 for two years. Then my doc suggested I go without the Lupron... I did for 8 months, and my PSA climbed to 4. Back on Lupron, and it dropped to zero. Did Lupron for another year, then went off of it again. Why? The side effects: bad arthritis, hot flashes, weight gain, 30 lbs in the first two months, then no more. No libido, and everything shrinks. No body hair. It was a joy to get off that stuff for a while, but my PSA started climbing again. Now back on Lupron, but no change in PSA. Went to a monthly shot, my PSA stayed at 4. Added Casodex, grew boobs, really bad. My PSA is now 2. I've been fighting cancer now for 6 years."

• Tar...
• Taken for 1 to 6 months
• January 23, 2016

For Prostate Cancer "Diagnosed with stage 4 metastatic prostate cancer involving bones. PSA was 130. Gleason score is a pair of bad 7s (4 3) and a pair of 8s. Also undergoing chemo with docetaxel. I've had 4 of 6 scheduled treatments. I also have xgeva injection monthly and Lupron quarterly. I've had one Lupron injection and 3 xgeva injections. After 42 days, PSA dropped to 2.9. Three weeks later, it was .7. That's a 98% drop each time. Was urinating 12 times a day, about 4 to 6 ounces at a time and storing 9 ounces all the time. First treatment was docetaxel, xgeva, and Lupron on the same visit. Relief was almost immediate. Eliminating 12 to 14 ounces now, 4 to 5 times a day. Also take prednisone twice a day until chemo is done. Side effects have been fairly nominal."

• Bur...
• July 1, 2017

For Prostate Cancer "Saving life is most important. However, so is quality of life. My husband of 30 years, the most stable, peaceful, fun, loving person I had ever met, completely disappeared with this drug. Physical side effects are horrible, but the potential psychological and emotional impact of this treatment can be even worse. And, it is not at all addressed by the medical community. He's gone for support, he's gone for counseling, but nothing seems to get through. The fact that he's alive apparently is not enough. So, after dealing with this for so many years, I would strongly suggest that couples fully deal with this together. Your husband or partner will become a completely different human being on this drug - and the impact is not reversible."

• Anonymous
• December 27, 2009

For Endometriosis "I just finished my 3-month course of shots. The first two months were not too bad, but the third month has taken its toll on me. I can deal with the hot flashes, but the joint pain has become very intense. The pain is disruptive, where my hands are aching all the time. It keeps me up at nighttime, and then lack of sleep becomes a problem. I wish they would suggest a joint therapy program for you to take if you need it because it's not like you can just call up your doctor and see him right away."

• WHE...
• Taken for less than 1 month
• March 29, 2016

For Prostate Cancer "Nov. 2012, I had a double lung transplant. July 2014, I was told I had prostate cancer (this after several PSA's that never dropped below 4. My last was in the high thirties, and I had had 3 biopsies). Had a radical surgery in November, which included nerve scraping and removal of 11 lymph nodes. Post-surgery, I had no radiation but did have the long-term Lupron injections twice. I was cancer-free for a year, and now it is back. Started Lupron again, and the side effects are already out in full force (after 4 days). Because of my compromised immune system and the medications I must take for life, and kidney issues as a result of the lung transplant, I worry that the Lupron will not work. What would be an alternative treatment?"

• Rid...
• Taken for 1 to 6 months
• April 4, 2017

For Prostate Cancer "I was diagnosed with prostate cancer in November of 2016. My PSA was 14.8, and my Gleason Score was 6. The good news is that the cancer did not spread outside the prostate and was in 9 out of 12 from the biopsy. I took Casodex for one month and had one Lupron injection, then started 44 treatments of radiation. Around treatment 20, my PSA went down to .09. After I complete radiation, I have one more Lupron injection to take, then that is it. No more cancer, I hope. The side effects are some hot flashes, weight gain, shrinking testicles, and frequent urination. After my next and last Lupron injection, I hope to be done with cancer."