User Reviews for Lupron
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Lupron.
Reviews for Lupron to treat Prostate Cancer
"I was diagnosed with prostate cancer in November of 2016 my PSA was 14.8 and my Gleason Score was 6. The good news is that the cancer did not spread outside to prostate and was in 9 out of 12 from the biopsy. I took Casodex for one month and had one Lupron injection then stared 44 treatments of radiation around treatment 20 my PSA went down to .09. After I complete radiation I have one more Lupron Injection to take then that is it no more Cancer I hope. The side effects are some hot flashes, weight gain, shrinking testicles and frequent urination. After my next and last Lupron injection I hope to be done with Cancer"
Ridgback (taken for 1 to 6 months) April 4, 2017
16 users found this comment helpful.
"Hot sweats were the thing most mentioned and most noticeable. My apologies for lack of empathy to all those who I've known going through them. Muscle mass loss and decreased exercise tolerance. My total weight lifted in a usual work out fell to about 1/3. Dry scaling skin and increased dry hair. However, my creeping male pattern baldness was certainly less noticeable. Testicular size and libido took a hit."
dOCwALT (taken for 1 to 6 months) February 13, 2017
19 users found this comment helpful.
"at age 60 biopsy showed prostate cancer psa was 10. had it out. After it was out, psa still ten. Started Lupron and psa dropped to 0 for two years. Then my doc suggested I go without the lupron... I did for 8 months and my psa climbed to 4. back on lupron and it dropped to zero. Did lupron for another year, then went off of it again. Why? The side effects, bad arthritis hot flashes, weight gain, 30 lbs in first two months, then no more. No libido and everything shrinks. No body hair. It was a joy to get off that stuff for awhile but my psa started climbing again. Now back on Lupron, but no change in psa. Went to a monthly shot, my psa stayed at 4. Added Casodex, grew boobs, really bad. My psa is now 2. I've been fighting cancer now for 6 years."
Fly4ever (taken for 5 to 10 years) January 13, 2017
25 users found this comment helpful.
"From the urologist, Lupron is a hormone to shrink the prostate prior to the x-ray treatments for cancer. I have lived with BPH for several years, and it did not shrink the prostate in my opinion. Subsequently, I learned from the Oncologist it was for lowering the PSA. and it did lower the PSA. The hormone was injected in the right and left gluteus muscles with the predicted soreness that passed with time. Three months prior to radiation; markers were placed in the prostate. After the markers were placed a second round of injections were required. This round resulted in a mistake, and the injection in the left gluteus resulted in the Sciatic nerve being punctured which has resulted in severe pain and soreness continuing to date."
Mr.Dee (taken for 6 months to 1 year) November 16, 2016
25 users found this comment helpful.
"Diagnosed with stage 4 with PC in my right hip. PSA for years was between 2.0 to 3.5. Went from 3.5 to 29 in one year ! I encourage all with a PSA of over 3.0 get a bone density test ! Started Luprone 30 day shot on July 5th 2016. First 3 months went from 29 to 3 so headed in the right direction. Bone pain reduced after first shot by more than 75%. Hot flashes around the clock roughly 10 to 12 a day with a intensity level of about a 5 or 6. Very annoying but tolerable. Miscellaneous aches and pains in joints and muscles. Occasional foggy headed and definitely wake up to much to pee. I'm trying Flo-max now I hope to see some improvement. Fatigue is real! I can't tell if this is harder on my Family than me! So far so good. God Bless to ALL!"
Mr Chuck October 26, 2016
46 users found this comment helpful.
"My PSA was rising after RP to 0.59. Started radiation with Lupron. If you exercise really hard with lots of caffiene, no sugar in the morning and minimal sugar all day long with high quality food, then the effects of Lupron are minimal other than the muscle pain and some joint pain. Sex life is about once a month. The more you exercise, the more likely you are able to have a sex life. After six months on Lupron I can still have sex. I took Bicalutimide with my first shot. I highly recommend to avoid the hot flashes"
Grumbly September 30, 2016
32 users found this comment helpful.
"I AM 87 AND HAVE BEEN TREATED WITH LUPRON FOR ABOUT 6 YEARS. I JUST HAD A CHECKUP AND MY PSA LEVEL WAS .430, MY LAST SHOT WAS IN APRIL. It is hard to tell when i will have another shot, i will check in with my doctor in four months, So far the only side effect is the hot flushing. It is fairly regular, last about 45 seconds or so and is a bit annoying, but considering it is keeping the cancer at bay i can live with it,"
tuppy August 30, 2016
40 users found this comment helpful.
"Diagnosed Stage 4 Prostate cancer-- July 2012--PSA=8 Radical Prostatectomy-- October 2012--PSA=0.6 Forty days radiation--April 2013---PSA=0.1 PSA=0.3---Jan 2015 PSA=1.0---March 2015 First Lupron Injection---April 2015--PSA=0.1 Second Lupron Injection--Oct 2015---PSA=0.1 Third Lupron Injection---April 2016---PSA=0.1 Fourth Lupron Injection---Oct. 2016--PSA=??? Lupron Injections accompanied by daily tablets of Bicalutamide. Side Effects: Penis shrinkage(afraid it will soon disappear), libido absent, hot flashes, some insomnia, increased neuropathy, some itching, inflammation in hands, extreme fatigue. All side effects manageable--beats being dead-- and has allowed me time to tie up loose ends and who knows--I may have years ahead!"
Nishpata August 5, 2016
45 users found this comment helpful.
"8 months into Lupron plus Casodex and I am refusing the next 3 month shot. PSA went from 5.7 to .2 to .1 and am just finishing up 9 weeks of radiation. GL scores were mostly 9's but no metastatic found. To say a less common side effect is loss of libido is just plain BS. About a month after the first shot I was done with sex, doc said once the testosterone is gone that's normal. Little aches and pains linger, balls shrink, lost all hair under my arms and slow growing elsewhere. Sometimes seem in a fog mentally. Hot flashes like you wouldn't believe till they offered me other meds, which help somewhat, Put on 5 lbs of blubber below the belly. Lack of energy as well. It works but I think DRs. keep you on it too long for Stage 1 or 2 cancers."
Len Pitts July 13, 2016
44 users found this comment helpful.
"Been on this drug 15 months No libido at all day sweats night sweats and hot flashes irritability and erratic memory episodes PSA from 30 to .01 after radiation and continues today"
Tom 1 June 16, 2016
37 users found this comment helpful.
"This is pure poison, I have very bad side effects from this poison and the doctor said he can do nothing, the physical and mental pain is so bad , hot flashes, very high blood pressure, head aches every day, pain urinating, joint pain, mental confusion , brain fog, memory loss, total itchy all over, sleeplessness , very bad fatigued, and a lot more, my doctor never told me anything about this poison just injected my with a 6 month supply, at 6,000.00."
albert owens (taken for 1 to 6 months) May 7, 2016
38 users found this comment helpful.
"Nov. 2012 I had a double lung transplant. July 2014 I was told I had prostate cancer (this after several PSA's that never dropped below 4. My last was in the high thirties and I had had 3 biopsies). Had a radical surgery in November which included nerve scraping and removal of 11 lymph nodes. Post surgery I had no radiation but did have the long term Lupron injections twice. I was cancer free for a year and now it is back. Started Lupron again and the side effects are already out in full force (after 4 days). Because of my compromised immune system and the medications I must take for life and kidney issues as a result of the lung transplant I worry that the Lupron will not work. What would be an alternative treatment?"
WHEEZERWILL (taken for less than 1 month) March 29, 2016
28 users found this comment helpful.
"Diagnosed with stage 4 metastatic prostate cancer involving bones. PSA was 130. Gleason score is a pair of bad 7s (4 3) and a pair of 8s. Also undergoing chemo with docetaxel. I've had 4 of 6 scheduled treatments. I also have xgeva injection monthly and lupron quarterly. I've had one lupron injection and 3 xgeva injections. After 42 days PSA dropped to 2.9. Three weeks later it was .7. That's a 98% drop each time. Was urinating 12 times a day about 4 to 6 ounces at a time and storing 9 ounces all the time. First treatment was docetaxel, xgeva and lupron on same visit. Relief was almost immediate. Eliminating 12 to 14 ounces now 4 to 5 times a day. Also take prednisone twice a day until chemo is done. Side effects have been fairly nominal."
Tarheel82 (taken for 1 to 6 months) January 23, 2016
41 users found this comment helpful.
"Doctors just give it out like cough medicine. I have a from of muscular distrophy , lupron almost killed me and the doctors did not know what to do. 11 years later I am still having side effects from the synthetic hormone. doctors should realize that one size does not fit all."
Inspector ll (taken for 10 years or more) January 9, 2016
24 users found this comment helpful.
"Stage 2B prostate cancer. Proton beam therapy coupled with six months on Lupron. Dreaded getting the second 3-month shot. Side-effects: Almost total loss of libido and sexual function within 30 days--lasting for several months post usage; debilitating hot flashes (2X/hour, 24/7); 15 pounds of weight gain; 50% increase in cholesterol under same diet; dangerous liver impact (GGT > 130) w/o alcohol use; significant breast growth."
Etienne1 October 31, 2015
32 users found this comment helpful.
"Have been getting monthly Lupron 7.5 mg injections since July 2014 (just had my 8th injection). No hot flashes; some mood swings and I recently started having arm and leg cramps a few times a week. Taking Casodex 50 mg daily as well, so it's hard to know which to blame. PSA was 205 when I started these meds and is now 0.03. I believe the complete lack of hot flashes may be due to receiving the monthly vs 3 or 6-month injection dose. I hope this information helps others."
WWII Vet (taken for 6 months to 1 year) February 18, 2015
92 users found this comment helpful.
"Prostate removed - huge 350 cc- Gleason 7, PSA 15, radiation for 8 weeks, Lupron every 3 months for one year, every 6 months for the next year and a half. PSA has been less than 0.01 since initial radiation. Weakness, memory problems and hot flashes but no cancer. Treatment is worth the side effects. I feel very lucky. "
Rustymart (taken for 2 to 5 years) February 6, 2015
80 users found this comment helpful.
"Had my first Lupron shot before 45 days of radiation. Having hot flashes,muscle and joint pain but not too bad. Doing the shot every 3 months. Psa went from 11.5 to 0.1. Next shot coming up in couple weeks. Don't have a problem with the shot or after having it. I think Lupron has been helping me, but everyone has different experiencies with it. Good luck to all you prostate cancer people."
olscout September 17, 2014
128 users found this comment helpful.
"I was 50, had my prostate removed then let it go at 55. Had a PSA above 400, my weight dropped to 105lbs thought I was going to die then had 15 radaiaton treatments and started Lupron shots. PSA dropped, I came back to life now I an 63 still getting Lupron shots every 6 months sure there are some side effects but its better than being dead if you have cancer. I hope something works for you."
walking dead....... (taken for 5 to 10 years) March 5, 2014
126 users found this comment helpful.
"Have been on Lupron for about 2 years and my stage 4 prostate cancer is now in remission. My prostate cancer specialist gets all the credit and kept side effects to a minimum with the help of other meds and supplements. I recommend Lupron."
Conmgr (taken for 2 to 5 years) October 2, 2013
146 users found this comment helpful.
"I have been on Lupron for two years. I got my last shot in December. It has kept my PSA under .03. Can't wait to see if it is still that low after 3 months! You learn to live with the side effects."
1968gto (taken for 2 to 5 years) February 26, 2013
120 users found this comment helpful.
"I got this shot about two years ago. I was told by the urologist that it was a one month shot. I had the shot becaue we wanted some time to research and decide what treatment would be best. Found out later that it was a 3 month shot! Suffered severe side effects! PSA dropped from 13 to 7, but the side effects were NOT worth it! Hot flashes with some of them causing me to nearly pass out were often (20 a day), memory problems, muscle/joint pain and on and on! Once, while teaching I suddenly didn't know where I was or what I was doing! After radiation I was recently put on Trelstar on a MONTHLY basis, nearly the same side effects but NOT the really bad ones!"
blessedhighfavor (taken for 1 to 6 months) December 18, 2012
88 users found this comment helpful.
"My cancerous prostate was removed when I was 65, 6 years ago. I receive a 22.5 mg Lupron injection about every 3 months. My PSA decreases each time from about 2 to undectable. The injection area is sore for 2-3 days after each injection. I have perhaps a dozen relatively minor hot flashes daily. I take 4 venlafaxine hcl 75 mg tablets daily to curtail hot flashes."
Anonymous June 11, 2012
97 users found this comment helpful.
"Had 1st shot 11/10/11, PSA was at 182, tested 3 weeks later, PSA had dropped to 3.3. Have prostate, metastatic bone and lymphatic cancer. This combined with radiation therapy, greatly improved my mobility (pelvis, hips fully involved, as well as on and inside spine). Side effects are hot flashes and night sweats, but other than that manageable for the relief I've gotten."
mdo333 January 4, 2012
128 users found this comment helpful.
"Recently received my first Lupron injection. Within one week my PSA dropped from 69.7 to 11. I have not noticed any severe side effects a of today. I am also starting Alendronate Sodium tablet for healthier bones."
Inline Don December 30, 2011
86 users found this comment helpful.
More about Lupron (leuprolide)
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- 55 Reviews – Add your own review/rating
- Drug class: gonadotropin releasing hormones