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User Reviews for Synvisc-One

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Condition Avg. Ratings Reviews Compare
Osteoarthritis
6.1
   
97 reviews 353 medications
Not Listed / Other
5.5
   
3 reviews
Summary of Synvisc-One reviews 6.1 100 reviews

Reviews for Synvisc-One

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For Osteoarthritis "Bottom line - I think the Synvisc One really helped the knee joint function but the side effects for me were so bad I will never use it again. Severe osteoarthritis both knees. Had Synvisc One injections in both knees early Dec 2017. The injections were brutally painful - and I’m not normally bothered by pain. Not sure I could bring myself to do it again. I was barely able to walk for 3 days, then developed constant, deep aching pain, swelling and stiffness in both legs from toes to hips that did not respond to ibuprofen or lidocaine patches. Ended up having steroid injections twice to control the side effects. After the last one I lost 6 lbs in 2 days fluid out of my legs. Now it is mid-April 2018 and I can tell the side effects are becoming less - and the mechanical knee joint pain and instability are returning. It’s too bad that I experienced such severe side effects because I think the Synvisc was actually very effective with the joint mobility and pain."

   
6.0

Wobblyknees (taken for 1 to 6 months) April 15, 2018

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For Osteoarthritis "After reading the reviews of those who have had the Synvisc shots, I am surprised at the level of pain some are describing. My ortho doc did tell me that some people don’t react well, that their knees “blow up”, esp. after the 4th or 5th time, and if that were to happen, to come right back. Maybe I am just lucky - no bad reaction, just pain free. It takes about 4 wks for the injection to take full effect. My first shot of Synvisc One was May 2016. It was not painful to have the shot, as my rheumatologist also used some local with it. Within a month, I was pain free in my knee. I previously was wearing a brace on my knee. Since then, I have had the shot every 6-8 mths in my left knee (from my ortho doc) I occasionally have a “little” pain if I overdo things, but it goes away once rested for a bit. I’ve had the shot 4 times now; just a couple days ago was the last time. Only tiny bruise at the site, and very slight swelling. That’s it. Worth it not to have pain for 6-8 months."

   
10

Babynurse March 19, 2018

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For Osteoarthritis "I had a 15’ fall through a ceiling and onto a staircase back in 1993. Many years of misdiagnosis, as well as poor MRI imaging in the late 90’s finally improved in 2017. All that time before could be ruined from random pain and swelling to my right ankle. It would make it very difficult to walk. Last year, the new MRI revealed blunt trauma to my right ankle. I knew it was from my big fall and I was curious what the solution would be. The surgeon recommended Synvisc-one. He said that it would give me relief for at least 6 months. It was Feb 1, 2017 when I received the shot and it’s now May 14, 2018 and I’m STILL PAIN FREE."

   
10

Daz (taken for 1 to 2 years) March 13, 2018

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"I tore/obliterated my Anterior Cruciate Ligament (ACL) had my meniscus cut and sewn back together on both sides, had 2 surgeries, drained 30cc of fluid from the ACL joint t one point, and lots of $$ PT. After 2 years after the accident I still was unable to bend my knee fully. I tried regular cortizone shots but they only were lasting a month before the pain would come back. The doctor said it was not good to get a lot of cortizone shots. So I did my research and found this gel. I asked him about it and he agreed that it might be a good try. It maybe took 2 weeks before I started to notice a difference. I was uncomfortable for a few days right after but nothing major. This was all 3 years ago since I had the shot and I have not had one issue since. I'm back to normal and no side effects or signs of slowing down :)"

   
10

ks (taken for 2 to 5 years) February 26, 2018

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For Osteoarthritis "Could barely walk. Osteoarthritis in both knees. Swelling all the time. Did the 3 injections in each knees. The pain was severe for 3 weeks. After then, knees are loosened up, swelling went down. I have a bit more movement, a bit more endurance, and bit less pain. I'm not sure I will go through the 3 weeks of severe pain for the amount of relief. If my insurance didn't cover it, I not have done it. Almost $3000.00 Canadian."

   
5.0

Take it or leave it February 14, 2018

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For Osteoarthritis "I had this treatment about 7 months ago and it worked very well for me. I just had another injection 2 days ago and I already feel better walking on it."

Country2 (taken for 6 months to 1 year) February 3, 2018

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For Osteoarthritis "Received the injection. A week went by no change as did the second week. Towards the end of 3rd week it started to kick in. I'm back on the treadmill with just slight discomfort due to fact I need a knee replacement. If this gives me 6 months of relief I'd give a 10+ rating but it's too early to tell. I gave up on cortisones they would last a few weeks at best and would shoot my blood sugars up. I'm praying to buy some time, I'm only 51 yrs old."

   
8.0

Rich B. (taken for 1 to 6 months) January 20, 2018

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For Osteoarthritis "I’ve had maybe 5 double injections of Synvisc One, and a few others of regular Synvisc prior. Always very painful for about a week (unable to walk for maybe 3 days, then slowly better). It usually takes a month or two for me to notice but I get to very little knee pain and better range of movement (for about 9 months each time). Yet, this time we also did one hip... and I think it was once too much. I reacted badly to the hip injection and 6 weeks after the injections I am back to where I was before the injections, knee-pain wise. So I would recommend the product, it helped me a lot, for many years... but it seems your body can get a tolerance (or intolerance?) to it and it can’t be a long term solution."

   
7.0

DanzAD December 17, 2017

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For Osteoarthritis "I had the Synvisc 1 over a year ago in my left knee, I work 12 hour days and am on my feet a lot. I am still satisfied with the results."

   
10

Debbieg952 (taken for 1 to 2 years) November 8, 2017

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For Osteoarthritis "Consulted with the surgeon two weeks ago. After he reveiwed x rays and MRI he thought I should wait a little longer for knee replacement ( I wasn't in much pain that day, so I didn't protest) He suggested the Synvisc One treatment (cortisone injection had only given me relief for 3 weeks) . My life has been pure agony for the past two weeks. Alternating between Voltaren and Tramadol, missing work and wondering if I made a mistake. I also had pain up the side of my leg almost to my hip. Couldn't understand it until I read a review here where someone said the same thing. Anyway, this morning suddenly I feel better. I don't want to jinx it so I'll just say that if it takes two weeks to kick in then I can live with that."

Goldie's Mom October 16, 2017

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For Osteoarthritis "Following on from my previous comments, it has been three weeks since I had the injections and the right knee drained (twice). After resting and icing for two weeks, I am now back to normal. No more popping/clicking. Started walking last week and slowly built up the distance. Walked 8km this morning and had no problems. Just needed to stretch before and after, which I should be doing anyway. Hope to get another 9 months out of it. Am willing to put up with 2-3 weeks of pain to get 9 months of relief (and a life)."

   
7.0

Didn't mind it September 27, 2017

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For Osteoarthritis "Sept 2017-Looks like I am not alone. It has been 20 days since injection. I have fluid build up and cannot bend my knee. Finding it hard to walk as I cannot bend knee. I wished I read reviews before getting injection."

Gauchi (taken for less than 1 month) September 27, 2017

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For Osteoarthritis "Had Synvisc 1 injection Sept 14 2017. Injection was very painful but well worth it. With injection and continued physical therapy 100% improved in first week. I did have acid refluxed 3 hours after the injection but I do have food allergies and discussed this with my Orthopedist before receiving the injection. This injection may not be for everyone but is definitely for me."

   
10

Miss Hat Lady September 22, 2017

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For Osteoarthritis "I have severe arthritis in my right knee I had arthroscopic surgery 20 years ago and now I am in need of a knee replacement. I have been getting Cortizone injections and thought I might try Synvisc . I Had first injection Monday, September 11 and the next day I had swelling and severe pain . I have been in pain since I can barely walk I didn't know I have this kind of pain before I had this injunction . And due to get another on Monday but I'm not going to do it I'm in too much pain it's not worth it !"

Anonymous (taken for less than 1 month) September 14, 2017

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For Osteoarthritis "I had my first shot of Synvisc in my right knee in February 2016 as it kept clicking/popping due to OA. Found the first shot to be amazing. Was walking normally the next day. Six weeks later decided to have my left knee done. Again, amazing, I could walk without any problems. 6-7 months later I had both knees done at the same time. Lost some weight, rode exercise bike and walked a lot. This time, I had nine months of relief. Went back for third round. Had Synvisc in right knee and anther product in left. No problems with left knee, but right knee swelled up and had to be drained (twice). I had obviously built up a sensitivity to it. Right knee is back to clicking/popping every couples of steps, which is really annoying."

Didn't mind it (taken for less than 1 month) September 10, 2017

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For Osteoarthritis "I just got the injection at 4:30. It is now 6 PM and I can not walk on my leg. My side of my thigh hurts. The nurse took me to my car in a wheelchair because I could not walk. She said she has never seen anyone react that way. People get the injection and walk out. Not me. I will never get that injection again. The pain afterwards was horrible"

Veh August 22, 2017

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For Osteoarthritis "I am experiencing more pain 2 weeks post injection than I had prior to it. I have a great deal of stiffness. My knee is locked up and when walking will buckle under me. The injections are very painful, and the doctor must have irritated a nerve, because I'd have severe pain at the injection site from just brushing touch. Never, ever again!"

   
1.0

Pssdandinpain (taken for less than 1 month) August 6, 2017

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For Osteoarthritis "After suffering acute hip pain ,femer odema, shock wave therapy,MRI scans revealed loss of cartilage and some arthritis ,I had a cortizone injection which worked for 2 weeks and back to 10/10 pain .I had the Synvisc-one injection which was very painful and had no effect for 4 weeks after which every day mobility improved and pain free movement ,with regular physiotherapy the mobility continues to improve every day after the treatment 4 months ago and I hope the results continue .100% recommend the product ,thanks so much for my improved quality of life ."

   
10

Snowy198316 August 2, 2017

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For Osteoarthritis "Had my first injection of Syn-visc 1 yesterday and have first total relief from knee pain in 10 years. The injection was not as painful as my cortisone injections. Hope I can stay pain free for a long time."

   
10

Anonymous July 30, 2017

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For Osteoarthritis "2nd Shot of Synvisc in 8 months. I had worse knee pain and discomfort and develop severe muscle hip pain. A $1000 a shot!! I feel that originally I had minimal relief but feel that this drug is overrated. I had to have a Cortisone shot which gave me comfort and relief from severe pain and it was only $20! If need be I can get one every (3) months but most people will receive the injection every (6) months. A new drug is going to be released soon after it's trial and it is called Ampe. I am hoping that it will be successful. No one wants to get their knee replaced and it is a final result . . ."

audio217 (taken for 6 months to 1 year) July 11, 2017

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For Osteoarthritis "After making the mistake of reading reviews of this treatment on a few sites - I felt I had to share my experience. What I had read scared me and made me pretty anxious. First off - about me. Mid 50s - way overweight and the knee I was working with had torn cartilage removed in late 80s. Didn't work. Now bone on bone and it crunches when I bend or move it wrong way I had the Synvisc 1 treatment 2 days ago and it started with a needle for the freezing. Then a needle for the steroid. Finally the S1. When it was done, I felt good - no pain or anything so I attributed that maybe to the freezing. Pain is now almost gone - very little bone crunching. GP said 2-3 wks for full potential. Cant wait. I recommend but every individual is different"

   
9.0

Canada Fat Guy (taken for less than 1 month) July 1, 2017

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For Osteoarthritis "I received the synvisc one injection 3 months ago, it did not help my pain ,it causes me more pain and suffering. I barely can walk or sleep. The back of my knee after waking up to start my day, I can't bend my knee without extremely pain. A week after injection I had started dragging my leg because the pain is unbearable. How can I have this injection removed from my knee. I can't live with this very very very very bad pain from the synvisc one injection. the back and front of my knee is agony."

   
1.0

I don't have a nickname June 25, 2017

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For Osteoarthritis "I'm not entirely sure which Synvisc injection I just received in both knees, perhaps Synvisc-One as the physician said it could provide pain relief for up to 6 months... I was, periodically, taking Ibuprofen when my knee pain flared up. Anyway, immediately after he injected both knees they felt much better. I thought, maybe, there was some type of Novocaine combined with the injection, but I think the pain relief was most likely just the Synvisc. It's now been almost 48 hours since the injections and I would say my pain reduced dramatically and immediately. I hope it does last for up to 6 months. Your "mileage" may vary, but I hope it works as well for you as it seems to be doing for me. -Nat-"

   
9.0

Anonymous June 24, 2017

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For Osteoarthritis "I had this injection, and I am now very crippled. The pain is intense. I cannot recommend this treatment. I wish I had never done it. Insult to injury it is expensive, and I am stuck paying for it."

Sierrafox (taken for 1 to 6 months) June 24, 2017

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For Osteoarthritis "I had my first Synvisc-One injections in both knees 4 weeks ago. Had the recheck with the Ortho today. Pain improvement took 3 days. Some mild heat and swelling the day after but didn't last long. Injection site was a bit painful for about 3/4 days but completely tolerable. The Dr's projection is that I should get 6 months out of. These injections help me tremendously! My knees aren't 100% but never will be again anyway. My mobility and pain level improvement is easily 60% if not a bit more. I'm thrilled! Ortho specialist has recommended bicycle or eliptical as appropriate exercise. Very happy there has been this much improvement in such a short time!"

jamaicaluvin (taken for less than 1 month) June 23, 2017

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