Skip to Content

User Reviews for Synvisc-One

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Condition Avg. Ratings Reviews Compare
Osteoarthritis
6.1
   
106 reviews 349 medications
Summary of Synvisc-One reviews 6.0 106 reviews

Reviews for Synvisc-One

Sort by:

"I had the synvisc injection and exactly 30 days later my knee was swollen. Couldn’t bend, drive, barely walk. Dr ordered an MRI it was clear. Doctor drained my knee and said it was an allergic reaction to this gel injection. Started to swell again within the hour of having it drained. Call his office and was told this can happen and to just stay off my knee. Ice, ibuprofen. I just don’t understand how I can get an allergic reaction to something that’s been in my body for 30 days. This was a mistake I should have never tried this."

   
1.0

Purplegreengrass (taken for less than 1 month) September 27, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I had Synvisc put into both knees at the same time as I had arthroscopy on left knee. Both knees felt like they had lumps of concrete in them for 6 mths. They were heavy and my movement was restricted and painful. Never ever ever again !!"

   
1.0

Westie (taken for 6 months to 1 year) September 20, 2018

0 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "55 year old male with arthritic knee. Had one Synvisc one injection July 30th 2018 (Lot number 8rslo11). I was in hospital with infection 2 days later with 3 arthroscopic surgeries to clean out infection. I contracted staph aureus bacteria in blood from injection. I can't walk, I have horrible pain, swelling in thighs, myocitis (muscle inflammation) due to infection. In hospital 20 days. May not be able to have knee replacement in future due to this infection."

   
1.0

Texasathlete (taken for less than 1 month) August 28, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I have been getting the synvisc one shots for years. The first time I had the 4 shots. After about a month I was doing great.. it lasted about 2 years. Then my next shot lasted about a year. I went to every 6 months with the shots and now I am back to one each year. This medicine is about the best.. it works for me. Thanks to my Doctor and this medicine I am able to keep working and living a normal life."

   
10

Paul (taken for 5 to 10 years) August 9, 2018

3 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I have bilateral knee osteoarthritis that responded well to cortisone, but after 3 courses, the relief only lasted 1 month. I chose synvisc-one (single injection) and just received my fourth dose. The previous injections lasted 6 months and they are a blessing! Yes, one dose has a lot of pressure, but you are done. I am one of the lucky ones who has virtually had no complications with any injections. I am back to playing pickleball after 48 hours! I strongly recommend synvisc-one when cortisone stops working; to delay surgery as long as possible."

   
10

Fat stew (taken for 1 to 6 months) August 6, 2018

2 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Had first round of shots in left and right knees last year which lasted 9 months. Due to my limited mobility and obesity Doc recommended I do low impact water aerobics and NO MORE pavement walking. The shots worked with 80 % relief and hardly any sharp pains or clicking only once is a while if I turned funny the knees would "catch" so this med was great! Lost 38 pounds in 9 months now walking on trails again and able to do slow flow and fundamental yoga so have moved up from just swimming! Ready to lose the last 60 pounds! Had second shots today and my legs felt very fatigued walking a mild 20 min stroll tonight. I have a headache and a little nausea but not bad. Doc advice was to get as light and lean as possible in a healthy weight range. I look forward to it - that's my plan. Best of luck and light to us all!"

   
9.0

Trayann (taken for 2 to 5 years) August 4, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "It is going on 4 wks and I have severe fluid build up I have called doctors office 4 times and was told to give it time to work ... what advice do anybody have this is making me depressed.. I had this injection on june 14th still no relief"

   
4.0

Nia (taken for less than 1 month) July 12, 2018

3 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I received 1 shot in my right knee about 2 months ago. I wasn't really in much pain before the shot. I had torn meniscus surgery in the beginning of February and was told this shot would help my arthritis. I have pain in both my knees now, my lower back is in pain, I actually feel worse than I did before the shot. Right knee is swollen a bit and went back to ortho doc who said I have a little fluid build up and to keep taking ibuprofen and if not cleared up in a month he will remove fluid. The only explanation I have is these side effects came from the shot and has not helped me one bit. I wonder if anyone else has these side effects."

   
1.0

countryozgirl (taken for 1 to 6 months) June 14, 2018

6 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "On 3/24/18 I had SynVisc One in both knees at the same time. I got a bit flushed, nauseous, and like I would faint right after. Used a wheelchair to get to the car as my legs were very stiff and heavy feeling afterwards. Had a spray cool numbing agent before shots, neither were very painful. Got shots on the outside of both knees which the dr said was usually less painful. One knee got about 90% relief the first week, the other only about 30%. Then I fell on both knees down a concrete step 14 days after injections which didn't help my situation. I waited for 5 weeks after injections, icing frequently mostly for the fall issues. I now had about 40% and 75% relief so on 5/1/18 went for appointment and they suggested a cortisone shot on top of the SynVisc One injection and I had some more relief after that, even though cortisone shots had never helped me before. I got 1 it in both knees, which hurt way more than the initial injection. But it worked. I am now about 85% & 90% relief!!! On 5/28/18."

   
9.0

Dawn May 29, 2018

3 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Had the 3 shots all together , shot worked very well forgot I had the problem that’s how effective however it’s 7 months now n I’m feeling that knife turning again in my knee so going to do it again. I just wish it stayed longer but it’s well worth the shot . No serious side effects .. this shot is a blessing"

   
10

Bobbie (taken for 1 to 6 months) May 24, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Bottom line - I think the Synvisc One really helped the knee joint function but the side effects for me were so bad I will never use it again. Severe osteoarthritis both knees. Had Synvisc One injections in both knees early Dec 2017. The injections were brutally painful - and I’m not normally bothered by pain. Not sure I could bring myself to do it again. I was barely able to walk for 3 days, then developed constant, deep aching pain, swelling and stiffness in both legs from toes to hips that did not respond to ibuprofen or lidocaine patches. Ended up having steroid injections twice to control the side effects. After the last one I lost 6 lbs in 2 days fluid out of my legs. Now it is mid-April 2018 and I can tell the side effects are becoming less - and the mechanical knee joint pain and instability are returning. It’s too bad that I experienced such severe side effects because I think the Synvisc was actually very effective with the joint mobility and pain."

   
6.0

Wobblyknees (taken for 1 to 6 months) April 15, 2018

3 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "After reading the reviews of those who have had the Synvisc shots, I am surprised at the level of pain some are describing. My ortho doc did tell me that some people don’t react well, that their knees “blow up”, esp. after the 4th or 5th time, and if that were to happen, to come right back. Maybe I am just lucky - no bad reaction, just pain free. It takes about 4 wks for the injection to take full effect. My first shot of Synvisc One was May 2016. It was not painful to have the shot, as my rheumatologist also used some local with it. Within a month, I was pain free in my knee. I previously was wearing a brace on my knee. Since then, I have had the shot every 6-8 mths in my left knee (from my ortho doc) I occasionally have a “little” pain if I overdo things, but it goes away once rested for a bit. I’ve had the shot 4 times now; just a couple days ago was the last time. Only tiny bruise at the site, and very slight swelling. That’s it. Worth it not to have pain for 6-8 months."

   
10

Babynurse March 19, 2018

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I had a 15’ fall through a ceiling and onto a staircase back in 1993. Many years of misdiagnosis, as well as poor MRI imaging in the late 90’s finally improved in 2017. All that time before could be ruined from random pain and swelling to my right ankle. It would make it very difficult to walk. Last year, the new MRI revealed blunt trauma to my right ankle. I knew it was from my big fall and I was curious what the solution would be. The surgeon recommended Synvisc-one. He said that it would give me relief for at least 6 months. It was Feb 1, 2017 when I received the shot and it’s now May 14, 2018 and I’m STILL PAIN FREE."

   
10

Daz (taken for 1 to 2 years) March 13, 2018

4 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I tore/obliterated my Anterior Cruciate Ligament (ACL) had my meniscus cut and sewn back together on both sides, had 2 surgeries, drained 30cc of fluid from the ACL joint t one point, and lots of $$ PT. After 2 years after the accident I still was unable to bend my knee fully. I tried regular cortizone shots but they only were lasting a month before the pain would come back. The doctor said it was not good to get a lot of cortizone shots. So I did my research and found this gel. I asked him about it and he agreed that it might be a good try. It maybe took 2 weeks before I started to notice a difference. I was uncomfortable for a few days right after but nothing major. This was all 3 years ago since I had the shot and I have not had one issue since. I'm back to normal and no side effects or signs of slowing down :)"

   
10

ks (taken for 2 to 5 years) February 26, 2018

2 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Could barely walk. Osteoarthritis in both knees. Swelling all the time. Did the 3 injections in each knees. The pain was severe for 3 weeks. After then, knees are loosened up, swelling went down. I have a bit more movement, a bit more endurance, and bit less pain. I'm not sure I will go through the 3 weeks of severe pain for the amount of relief. If my insurance didn't cover it, I not have done it. Almost $3000.00 Canadian."

   
5.0

Take it or leave it February 14, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I had this treatment about 7 months ago and it worked very well for me. I just had another injection 2 days ago and I already feel better walking on it."

Country2 (taken for 6 months to 1 year) February 3, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Received the injection. A week went by no change as did the second week. Towards the end of 3rd week it started to kick in. I'm back on the treadmill with just slight discomfort due to fact I need a knee replacement. If this gives me 6 months of relief I'd give a 10+ rating but it's too early to tell. I gave up on cortisones they would last a few weeks at best and would shoot my blood sugars up. I'm praying to buy some time, I'm only 51 yrs old."

   
8.0

Rich B. (taken for 1 to 6 months) January 20, 2018

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I’ve had maybe 5 double injections of Synvisc One, and a few others of regular Synvisc prior. Always very painful for about a week (unable to walk for maybe 3 days, then slowly better). It usually takes a month or two for me to notice but I get to very little knee pain and better range of movement (for about 9 months each time). Yet, this time we also did one hip... and I think it was once too much. I reacted badly to the hip injection and 6 weeks after the injections I am back to where I was before the injections, knee-pain wise. So I would recommend the product, it helped me a lot, for many years... but it seems your body can get a tolerance (or intolerance?) to it and it can’t be a long term solution."

   
7.0

DanzAD December 17, 2017

4 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I had the Synvisc 1 over a year ago in my left knee, I work 12 hour days and am on my feet a lot. I am still satisfied with the results."

   
10

Debbieg952 (taken for 1 to 2 years) November 8, 2017

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Consulted with the surgeon two weeks ago. After he reveiwed x rays and MRI he thought I should wait a little longer for knee replacement ( I wasn't in much pain that day, so I didn't protest) He suggested the Synvisc One treatment (cortisone injection had only given me relief for 3 weeks) . My life has been pure agony for the past two weeks. Alternating between Voltaren and Tramadol, missing work and wondering if I made a mistake. I also had pain up the side of my leg almost to my hip. Couldn't understand it until I read a review here where someone said the same thing. Anyway, this morning suddenly I feel better. I don't want to jinx it so I'll just say that if it takes two weeks to kick in then I can live with that."

Goldie's Mom October 16, 2017

9 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Following on from my previous comments, it has been three weeks since I had the injections and the right knee drained (twice). After resting and icing for two weeks, I am now back to normal. No more popping/clicking. Started walking last week and slowly built up the distance. Walked 8km this morning and had no problems. Just needed to stretch before and after, which I should be doing anyway. Hope to get another 9 months out of it. Am willing to put up with 2-3 weeks of pain to get 9 months of relief (and a life)."

   
7.0

Didn't mind it September 27, 2017

12 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Sept 2017-Looks like I am not alone. It has been 20 days since injection. I have fluid build up and cannot bend my knee. Finding it hard to walk as I cannot bend knee. I wished I read reviews before getting injection."

Gauchi (taken for less than 1 month) September 27, 2017

8 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "Had Synvisc 1 injection Sept 14 2017. Injection was very painful but well worth it. With injection and continued physical therapy 100% improved in first week. I did have acid refluxed 3 hours after the injection but I do have food allergies and discussed this with my Orthopedist before receiving the injection. This injection may not be for everyone but is definitely for me."

   
10

Miss Hat Lady September 22, 2017

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I have severe arthritis in my right knee I had arthroscopic surgery 20 years ago and now I am in need of a knee replacement. I have been getting Cortizone injections and thought I might try Synvisc . I Had first injection Monday, September 11 and the next day I had swelling and severe pain . I have been in pain since I can barely walk I didn't know I have this kind of pain before I had this injunction . And due to get another on Monday but I'm not going to do it I'm in too much pain it's not worth it !"

Anonymous (taken for less than 1 month) September 14, 2017

8 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

For Osteoarthritis "I had my first shot of Synvisc in my right knee in February 2016 as it kept clicking/popping due to OA. Found the first shot to be amazing. Was walking normally the next day. Six weeks later decided to have my left knee done. Again, amazing, I could walk without any problems. 6-7 months later I had both knees done at the same time. Lost some weight, rode exercise bike and walked a lot. This time, I had nine months of relief. Went back for third round. Had Synvisc in right knee and anther product in left. No problems with left knee, but right knee swelled up and had to be drained (twice). I had obviously built up a sensitivity to it. Right knee is back to clicking/popping every couples of steps, which is really annoying."

Didn't mind it (taken for less than 1 month) September 10, 2017

10 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

Page 1 2 3 4 5
Hide