Synvisc-One and Discomfort: What Users Say

• Car...
• July 9, 2019

For Osteoarthritis "I had two prior series of Synvisc-One injections and had some relief. I get a lidocaine shot before each injection to help with pain. This third series has been awful. I have been in agony and have not been able to walk. My left leg calf muscles felt like they were being ripped apart. I was literally in tears daily. I did tell the medical staff of my pain. Third injection was almost two weeks ago and I am still in agony much of the time. Only when I have a full dose of prescription and OTC pain meds, plus lidocaine and other topical applications, in my system do I get relief. And I have to be very careful as to how I move, so as to not jar the leg and start the pain. I have been worse off than I ever was before."

• Rob...
• October 18, 2014

For Osteoarthritis "I had a Synvisc-One shot about 7 months ago in my right knee. The injection was not painful at all - just uncomfortable as the thick fluid goes into the knee. I had pain relief for 6 full months. After this experience, I decided to get 2 shots - one in each knee. I had the shots done yesterday, and the pain from the shots was excruciating. The experience was nothing like the first time. I felt like I was going to pass out and as if I had been 'sucker punched' in the gut. I couldn't get off the exam table for 20 minutes and could barely get in my car to drive home. I was in such pain and discomfort I went to bed and slept for 12 hours. Today, I still have discomfort and aching."

• Lam...
• September 29, 2015

For Osteoarthritis "I had the original Synvisc 3 in my left knee with no measurable improvement and ultimately had a complete knee replacement. My right knee is a complete success story. I have had four Synvisc One injections, and I am scheduled for another next month. The pain relief was incredible, yes, the shot itself is uncomfortable, but not excruciating. I have had anywhere from five to six months of relief each time. I would recommend this procedure to anyone."

• Boo...
• Taken for 1 to 6 months
• December 14, 2019

For Osteoarthritis "I had a Synvisc One injection to my shoulder after the MRI noted limited cartilage remaining, some tears, and arthritis. It was uncomfortable to painful for 7-10 days, and since then has been extraordinary. I have no pain and minimal discomfort with movement. I used to wake in pain during the night, but I am no longer bothered at all. I have gone back to powerlifting and am able to bench press with no problems. It has been incredible and is still effective five months in."

• aud...
• Taken for 6 months to 1 year
• July 11, 2017

For Osteoarthritis "2nd shot of Synvisc in 8 months. I had worse knee pain and discomfort and developed severe muscle hip pain. A $1000 a shot!! I feel that originally I had minimal relief but feel that this drug is overrated. I had to have a cortisone shot, which gave me comfort and relief from severe pain, and it was only $20! If need be, I can get one every 3 months, but most people will receive the injection every 6 months. A new drug is going to be released soon after its trial, and it is called Ampe. I am hoping that it will be successful. No one wants to get their knee replaced, and it is a final result..."

• ksa...
• Taken for 2 to 5 years
• February 26, 2018

"I tore/obliterated my Anterior Cruciate Ligament (ACL), had my meniscus cut and sewn back together on both sides, had 2 surgeries, drained 30cc of fluid from the ACL joint at one point, and lots of $$ PT. After 2 years after the accident, I still was unable to bend my knee fully. I tried regular cortisone shots, but they only lasted a month before the pain would come back. The doctor said it was not good to get a lot of cortisone shots. So I did my research and found this gel. I asked him about it, and he agreed that it might be a good try. It maybe took 2 weeks before I started to notice a difference. I was uncomfortable for a few days right after, but nothing major. This was all 3 years ago since I had the shot, and I have not had one issue since. I'm back to normal and no side effects or signs of slowing down."