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Hylan G-F 20 Dosage

Medically reviewed by Last updated on Sep 4, 2023.

Applies to the following strengths: 16 mg/2 mL; 48 mg/6 mL

Usual Adult Dose for Osteoarthritis

21 years and older:
Inject 16 mg (2 mL) intra-articularly into the knee once a week for 3 weeks


Use: For the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics (e.g., acetaminophen)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available



Safety and efficacy have not been established in patients younger than 21 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments


Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.