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Synvisc-One and Swollen Joints: What Users Say

Swollen joints: mentioned by 3 users (1.7%)

Based on user experiences from 174 Synvisc-One reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 42.0%
swelling 19.5%
stiffness 8.0%
severe pain 5.7%
allergic reaction 3.4%
discomfort 3.4%
nausea 2.9%
soreness 2.9%
numbness 1.7%
swollen joints 1.7%

Reviews for Synvisc-One

  • Lov...
  • Taken for 1 to 6 months
  • September 29, 2016

For Osteoarthritis "I have always been a very active person. But I started to get a bulge around my left knee. Really not painful until I got back into heels. Then it ached. So I stepped down to my sneakers. If I did extreme lifting and carrying cases of water upstairs, that would ache. But I started hearing the grinding of my knee. I made an appointment with the ortho doc, got an MRI done of my knee. I needed a knee replacement! But I wasn't ready yet, even though I am getting up there, I surprise people all the time with what I still do. Got the shots, one in each knee. No big deal. 6 weeks later, I cannot walk, using crutches, in enormous pain. Knees so swollen and hard. Can't bend them. What do I do now?"

1 / 10
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24 Report
  • Pai...
  • Taken for less than 1 month
  • October 30, 2021

For Osteoarthritis "I am allergic to a lot of medicine but decided to try the 3 shots for osteoarthritis. For 3 weeks, I had sharp pains in my knee and hip. About 5 days after the third shot, that sharp pain went away. I walked my dog two days in a row - little guy, maybe 20 minutes. I woke up the next day with my knee so swollen and three inches above my knee. My doc removed fluid, super painful. This did nothing. It’s now been three days using a walker and being totally immobilized. I’m waiting to see if it’s an infection, but he doesn’t think so. I think it’s from the gel. I never had this happen to me before. Hoping after the weekend, he can do more to help. I won’t get this medicine again."

1 / 10
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0 Report
  • Ont...
  • March 4, 2016

For Osteoarthritis "Took this shot one week ago, the pain is worse. I wish I wouldn't have done it. Can't sleep, knee is swollen. I'm up all night!"

2 / 10
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44 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.